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Remote Python Engineer Jobs in Missouri (NOW HIRING)

AI Automation Engineer -Remote

Saint Louis, MO · On-site +1

$202K - $234K/yr

... Python, React and JavaScript * Excellent debugging skills and the ability to manage multiple ... remote work reimbursement, paid time off, employee assistance programs, and more. Benefits are ...

AI Automation Engineer -Remote

Columbia, MO · On-site +1

$202K - $234K/yr

... Python, React and JavaScript * Excellent debugging skills and the ability to manage multiple ... remote work reimbursement, paid time off, employee assistance programs, and more. Benefits are ...

... Python, React and JavaScript * Excellent debugging skills and the ability to manage multiple ... remote work reimbursement, paid time off, employee assistance programs, and more. Benefits are ...

AI Automation Engineer -Remote

Springfield, MO · On-site +1

$202K - $234K/yr

... Python, React and JavaScript * Excellent debugging skills and the ability to manage multiple ... remote work reimbursement, paid time off, employee assistance programs, and more. Benefits are ...

AI Automation Engineer -Remote

Kansas City, MO · On-site +1

$202K - $234K/yr

... Python, React and JavaScript * Excellent debugging skills and the ability to manage multiple ... remote work reimbursement, paid time off, employee assistance programs, and more. Benefits are ...

$83K - $113K/yr

You will collaborate with cross-functional teams in a remote-first environment where innovation ... Strong software engineering expertise with Go and/or Python, including the design, development ...

$44 - $58.50/hr

Develop automation tools and internal platforms using Go and/or Python to reduce manual operations ... Remote-first working model with flexible working hours (core hours 10am-3pm local time) * High ...

Work across the stack using TypeScript, Python, and SQL to deliver performant and scalable product ... Flexible remote-first working environment. * Home office setup budget of up to 2,800. * Opportunity ...

Data Engineer (MedInsight)

Saint Louis, MO · On-site +1

$93K - $177K/yr

Analyze and improve data intake processes and optimize SparkSQL/Python workloads for performance ... Location This role can be remote within the U.S. The expected application deadline for this job is ...

$68K - $92K/yr

Working knowledge of programming or scripting languages such as JavaScript, TypeScript, or Python is desirable. Benefits * Fully remote work environment with flexibility to work from anywhere in ...

Data Engineer (MedInsight)

Saint Louis, MO · On-site +1

$93K - $177K/yr

Analyze and improve data intake processes and optimize SparkSQL/Python workloads for performance ... Location This role can be remote within the U.S. The expected application deadline for this job is ...

Senior AI/ML Engineer

Jefferson City, MO · On-site +1

$99K - $136K/yr

Remote/Hybrid: This role is based remotely but if you live within a 50-mile radius of Sunnyvale, CA ... We own a modern full-stack architecture including TypeScript/React, Python, GraphQL, Golang , and ...

$120K - $290K/yr

Strong proficiency in Go, with additional experience in languages such as Python, Ruby, Rust, or ... Ability to thrive in remote, distributed engineering teams. Benefits * Competitive compensation ...

$80K - $110K/yr

It is a fully remote opportunity within a globally distributed engineering organization ... Proficiency in automation and scripting using PowerShell, PowerCLI, Python, Bash, or similar tools.

This is a remote position, which requires regular travel to client sites Monday - Friday. We ... Strong knowledge of one or more programming languages such as JAVA, C++, C, C#, Objective-C, Python ...

$94K - $124K/yr

Strong programming experience in one or several of Ruby , Go , Rust, C or Python (and willingness ... remote

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Showing results 1-20

Remote Python Engineer information

See Missouri salary details

$21.6K

$131.3K

$189.9K

How much do remote python engineer jobs pay per year?

As of Jun 18, 2026, the average yearly pay for remote python engineer in Missouri is $131,293.00, according to ZipRecruiter salary data. Most workers in this role earn between $103,600.00 and $154,300.00 per year, depending on experience, location, and employer.

What does a Remote Python Engineer do?

A Remote Python Engineer designs, develops, and maintains software applications using the Python programming language, all while working from a remote location. Their responsibilities typically include writing efficient code, troubleshooting issues, collaborating with team members through online tools, and integrating third-party APIs or libraries. They may work on web development, automation scripts, data analysis, or backend services depending on the company's needs. Remote Python Engineers must have strong communication skills and be comfortable using project management and version control tools like Git. This role is ideal for those who want the flexibility of working from home while contributing to software projects.

What are the key skills and qualifications needed to thrive as a Remote Python Engineer, and why are they important?

To thrive as a Remote Python Engineer, you need a strong command of Python programming, experience with software development best practices, and familiarity with frameworks like Django or Flask, often supported by a relevant degree or equivalent experience. Proficiency in version control systems such as Git, cloud platforms like AWS or Azure, and continuous integration tools is typically required. Excellent problem-solving abilities, self-motivation, and clear written communication are crucial for effective collaboration in a remote environment. These skills ensure high-quality code delivery, efficient teamwork across distributed teams, and successful project outcomes.

What are some common challenges faced by Remote Python Engineers, and how can they be overcome?

Remote Python Engineers often encounter challenges such as effective communication across time zones, maintaining productivity outside a traditional office, and ensuring code quality in distributed teams. To overcome these, it's helpful to use collaborative tools like Slack and GitHub, participate in regular virtual meetings, and follow clear coding standards. Actively documenting your work and reaching out proactively to teammates can also foster a sense of connection and streamline project workflows.

What is the difference between Remote Python Engineer vs Remote Data Scientist?

AspectRemote Python EngineerRemote Data Scientist
Required SkillsPython, APIs, software developmentPython, statistics, machine learning
Work EnvironmentSoftware development teams, coding, debuggingData analysis, modeling, research
Industry UsageTech, startups, software companiesFinance, healthcare, tech

While both roles require Python skills, Remote Python Engineers focus on building and maintaining software applications, whereas Remote Data Scientists analyze data and develop models. The roles often overlap in Python proficiency but differ in their core responsibilities and industry applications.

What are the most commonly searched types of Python Engineer jobs in Missouri? The most popular types of Python Engineer jobs in Missouri are:
What are popular job titles related to Remote Python Engineer jobs in Missouri? For Remote Python Engineer jobs in Missouri, the most frequently searched job titles are:
What job categories do people searching Remote Python Engineer jobs in Missouri look for? The top searched job categories for Remote Python Engineer jobs in Missouri are:
What cities in Missouri are hiring for Remote Python Engineer jobs? Cities in Missouri with the most Remote Python Engineer job openings:
Infographic showing various Remote Python Engineer job openings in Missouri as of June 2026, with employment types broken down into 1% Locum Tenens, 83% Full Time, 3% Part Time, and 13% Contract. Highlights an 87% Physical, 5% Hybrid, and 8% Remote job distribution, with an average salary of $131,293 per year, or $63.1 per hour.
AI Automation Engineer -Remote

AI Automation Engineer -Remote

Quora

Saint Louis, MO • On-site, Remote

$202K - $234K/yr

Full-time

Medical, Dental, Vision, PTO

Posted 27 days ago


Job description

About Quora:

Quora’s mission is to grow and share the world’s knowledge. To do so, we have two knowledge sharing products:

  • Quora: a global knowledge sharing platform with over 400M monthly unique visitors, bringing people together to share insights on various topics and providing a unique platform to learn and connect with others.
  • Poe: a platform providing millions of global users with one place to chat, explore and build with a wide variety of AI language models (bots), including o3, o4-mini, Claude 3.7 Sonnet, GPT Image 1 and more. As AI capabilities rapidly advance, Poe provides a single platform to instantly integrate and utilize these new models.

Behind these products are passionate, collaborative, and high-performing global teams. We have a culture rooted in transparency, idea-sharing, and experimentation that allows us to celebrate success and grow together through meaningful work. Join us on this journey to create a positive impact and make a significant change in the world.

About the Team and Role:

We’re hiring our first AI Automation Engineer to lead how we apply AI internally across the company. This is a unique opportunity to shape how LLMs become embedded in our daily operations. Your goal will be to automate as much work as possible, increasing our productivity and improving the quality of our products, decision-making, and internal processes.

You’ll work closely with teams across the organization to identify high-impact problems and solve them, continually assessing new potential as frontier model capabilities constantly improve. With access to a wide range of state-of-the-art models via Poe, and an organization focused on AI, you’ll be well placed to experiment, iterate quickly, and launch internal services.

This role is ideal for an engineer who’s curious, pragmatic, and motivated by real-world impact - not just research or prototypes. You’ll lay the groundwork for how we approach internal AI applications, with a focus on utility, trust, and constant adaptation.

Responsibilities:
  • Develop and maintain internal tools and systems that automate existing work and increase employee productivity using AI
  • Use AI as much as possible to automate your own process of creating this software
  • Collaborate with teams across the business to understand pain points and identify high-impact automation or process improvement opportunities
  • Rapidly prototype small AI-enabled utilities or automations and deploy them into production swiftly
  • Supervise the choices AI is making in areas like architecture, libraries, or technologies, and be ready to debug complex systems across frontend and backend services when AI cannot
  • Act as a high-trust owner of systems that may handle sensitive data or business-critical logic
  • Work cross-functionally to ensure tools are adopted and deliver obvious value
  • Stay updated on the latest models and tools, and apply that knowledge to your work
Minimum Requirements:
  • Availability for meetings and impromptu communication during Quora's “coordination hours" (Mon-Fri: 9am-3pm Pacific Time)
  • Experience creating LLM-backed tools involving prompt engineering and automated evals
  • 5+ years of experience in full-stack development with strong skills in Python, React and JavaScript
  • Excellent debugging skills and the ability to manage multiple projects simultaneously
  • High level of ownership and accountability, especially with sensitive or business-critical data
  • Strong communication skills and a collaborative mindset
  • Comfortable working in a fast-paced, sometimes ambiguous environment with shifting priorities
  • Experience working cross-functionally with teams outside of product development
  • A natural collaborator who enjoys being a partner and creating utility for others

At Quora, we value diversity and inclusivity and welcome individuals from all backgrounds, including marginalized or underrepresented groups in tech, to apply for our job openings. We encourage all candidates who share a passion for growing the world’s knowledge, even those who may not strictly meet all the preferred requirements, to apply, as we know that a diverse range of perspectives can have a significant impact on our products and our culture.

Additional Information:

We are accepting applications on an ongoing basis.

Quora offers a wide range of benefits including medical/dental/vision coverage, equity refreshers, remote work reimbursement, paid time off, employee assistance programs, and more. Benefits are country-specific and may vary. For more information on benefits, visit this link: https://www.careers.quora.com/benefits

There are many factors that will determine the starting pay, including but not limited to experience, location, education, and business needs.

  • US candidates only: For US based applicants, the salary range is $155,656 - $225,160 USD + equity + benefits.
  • Canada candidates only: For Toronto and Vancouver based applicants, the salary range is $202,383 - $234,201 CAD + equity + benefits. For all other locations in Canada, the salary range is $188,891 - $218,588 CAD + equity + benefits.

We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

Job Applicant Privacy Notice: https://www.careers.quora.com/applicant-privacy-notice