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How much do recombinant protein expression jobs pay per hour?

As of Sep 14, 2026, the average hourly pay for recombinant protein expression in the United States is $35.05, according to ZipRecruiter salary data. Most workers in this role earn between $25.48 and $41.59 per hour, depending on experience, location, and employer.

What is recombinant protein expression?

A Recombinant Protein Expression job involves producing proteins using genetic engineering techniques in host systems such as bacteria, yeast, insect, or mammalian cells. Professionals in this role design expression vectors, optimize expression conditions, and purify proteins for various applications, including research, therapeutics, and industrial use. The job often requires expertise in molecular biology, biochemistry, and protein purification techniques.

What does recombinant protein expression do?

Professionals in Recombinant Protein Expression typically spend their days designing and constructing DNA constructs, cultivating host cells (like E. coli, yeast, or mammalian cells), and optimizing conditions for protein expression and purification. Routine responsibilities may also include performing quality control assays, troubleshooting experimental issues, maintaining accurate lab records, and preparing reports for stakeholders or regulatory purposes. Collaboration with research scientists, bioinformaticians, or downstream processing teams is common, especially when tailoring protocols for different target proteins. This hands-on and collaborative environment offers a dynamic mix of experimentation and problem-solving each day.

What are the key skills and qualifications needed to thrive in recombinant protein expression?

To thrive in Recombinant Protein Expression, you need a solid background in molecular biology, biochemistry, or a related life sciences field, with experience in gene cloning, vector design, and protein purification techniques. Familiarity with laboratory equipment such as FPLC/HPLC systems, PCR machines, and relevant software (e.g., LIMS, protein modeling tools) is highly beneficial, and certifications in laboratory safety are often valued. Attention to detail, strong problem-solving abilities, and effective teamwork are essential soft skills for success in this field. These abilities ensure the efficient production of high-quality recombinant proteins, support scientific research, and facilitate collaboration within multidisciplinary teams.

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Recombinant Protein Expression jobs near you
Infographic showing various Recombinant Protein Expression job openings in the United States as of September 2026, with employment types broken down into 1% As Needed, 72% Full Time, 24% Part Time, 2% Contract, and 1% Nights. Highlights an 91% Physical, 2% Hybrid, and 7% Remote job distribution, with an average salary of $72,895 per year, or $35 per hour.

Scientist / Protein Purification

Cambridge, MA • On-site

Pioneer Data
Recruiting and Staffing Services • 51 - 200 employees
Learn more about Pioneer Dataexternal

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Re-posted yesterday

Job description

Position Details:
Our client, a world-leading Pharmaceutical Company in Cambridge, MA is currently looking for an Scientist to join their expanding team.
 
Job Title: Scientist / Protein Purification
Duration: 24 months contract, extendable up to 48 months
Location: Cambridge, MA
 
Note:
The client has the right-to-hire you as a permanent employee at any time during or after the end of the contract.
You may participate in the company group medical insurance plan
 
Job Description:
We are seeking a motivated Bench Scientist to join a biotherapeutics research team in Cambridge, MA.
This is a hands-on laboratory position focused primarily on recombinant protein expression, purification, and characterization to support downstream biotherapeutic research.

Key Responsibilities
Perform routine recombinant protein purification using FPLC/AKTA and related chromatography techniques.
Support the production of recombinant proteins and antigens for downstream biotherapeutic research.
Participate in protein expression workflows and, as needed, molecular biology/DNA-related activities.
Perform protein characterization and assess protein quality, purity, concentration, and suitability for downstream applications.
Work with antigens, antibodies, mAbs, Fabs, and other recombinant proteins.
Perform routine protein labeling and conjugation, including fluorescent and biotin labeling.
Assist with analytical techniques such as SDS-PAGE, Western blotting, and HPLC.
Maintain accurate laboratory records, sample tracking, and experimental documentation.
Manage multiple protein-production and purification requests while meeting project timelines.
Work collaboratively with scientists across the research organization and provide purified proteins for downstream studies.
Maintain a clean, organized, and compliant laboratory environment and follow all required laboratory safety and PPE procedures.

Required Qualifications
Bachelor's degree in Biochemistry, Biology, Chemistry, Molecular Biology, or a related scientific discipline.
At least 1 year of hands-on experience with recombinant protein purification or a closely related protein-science discipline.
Hands-on experience with AKTA/FPLC or comparable chromatography systems.
Understanding of protein purification and characterization principles.
Strong laboratory organization and time-management skills.
Ability to work effectively in a collaborative, fast-paced research environment.

Preferred Qualifications
Master's degree in Biochemistry, Biology, Biophysics, Molecular Biology, or a related field.
Experience with recombinant protein expression.
Experience with protein biophysics and protein characterization.
Experience working with antibodies, mAbs, Fabs, or recombinant antigens.
Background in immunology or biotherapeutic research.