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Quality Systems Manager Jobs in Raleigh, NC (NOW HIRING)

GSK

Quality Systems & Data Manager

Zebulon, NC · On-site

Manages implementation of local updates to site quality digital systems including VQMS, MERP through appropriate change management procedures. * Develop, implement, and monitor the Quality ...

Align Technology

Director, Quality Systems

Raleigh, NC · On-site

Lead and manage the Invisalign Multi-site QMS to ensure industry best practices and compliance with regulatory requirements. * Oversee the harmonization of quality system processes at various global ...

NCSU

Systems Manager

Raleigh, NC · Hybrid

It also strives to deliver high-quality, supplemental IT services designed to enhance students ... Essential Job Duties The Systems Manager is charged with technical leadership and executive ...

GSK

MES Systems Manager

Zebulon, NC · On-site

We manufacture and supply reliable, high-quality medicines and vaccines to meet patients' needs and ... You will lead the management, improvement, and support of Manufacturing Execution Systems (MES ...

GlaxoSmithKline

MES Systems Manager

Zebulon, NC · On-site

We manufacture and supply reliable, high-quality medicines and vaccines to meet patients' needs and ... You will lead the management, improvement, and support of Manufacturing Execution Systems (MES ...

LaBine and Associates

Quality Manager

Raleigh, NC · On-site

This role is responsible for elevating quality performance through process improvement, system ... Manage non-conformance processes including NCR, CAR, and SCAR * Drive root cause analysis and ...

LaBine and Associates

Quality Manager

Raleigh, NC · On-site

This role is responsible for elevating quality performance through process improvement, system ... Manage non-conformance processes including NCR, CAR, and SCAR * Drive root cause analysis and ...

LaBine and Associates

Quality Manager

Raleigh, NC · On-site

This role is responsible for elevating quality performance through process improvement, system ... Manage non-conformance processes including NCR, CAR, and SCAR * Drive root cause analysis and ...

LaBine and Associates

Quality Manager

Raleigh, NC · On-site

This role is responsible for elevating quality performance through process improvement, system ... Manage non-conformance processes including NCR, CAR, and SCAR * Drive root cause analysis and ...

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All JobsQuality Systems JobsQuality Systems Manager JobsQuality Systems Manager Jobs in Raleigh, NC

Quality Systems Manager information

See Raleigh, NC salary details

$52.5K

$95.9K

$149.7K

How much do quality systems manager jobs pay per year?

As of Jul 11, 2026, the average yearly pay for quality systems manager in Raleigh, NC is $95,855.00, according to ZipRecruiter salary data. Most workers in this role earn between $73,400.00 and $119,100.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a Quality Systems Manager, and why are they important?

To thrive as a Quality Systems Manager, you need strong expertise in quality management principles, regulatory compliance, and process improvement, typically supported by a degree in engineering or a related field. Familiarity with ISO standards (like ISO 9001), quality management software, and certifications such as Six Sigma or ASQ Certified Manager of Quality/Organizational Excellence are commonly required. Leadership, analytical thinking, and effective communication are crucial soft skills for coordinating teams and driving continuous improvement. These skills and qualifications are essential to ensure consistent product quality, regulatory adherence, and overall organizational efficiency.

What does a quality systems manager do?

A quality systems manager oversees the development, implementation, and maintenance of quality management systems to ensure products and processes meet industry standards and regulations. They analyze data, conduct audits, and coordinate with teams to improve quality, often using tools like ISO standards and quality management software. Strong leadership, attention to detail, and knowledge of compliance requirements are essential for this role.

What is the salary of a QA manager?

The salary of a Quality Systems Manager typically ranges from $80,000 to $130,000 annually, depending on experience, industry, and location. Senior roles or those in highly regulated industries may offer higher compensation, and certifications like Six Sigma can influence salary levels.

What is the difference between Quality Systems Manager vs Quality Assurance Manager?

AspectQuality Systems ManagerQuality Assurance Manager
Primary FocusDeveloping and maintaining quality management systems and processesOverseeing product testing and ensuring quality standards are met during production
CertificationsISO 9001 Lead Auditor, CQEASQ certifications, QA certifications
Work EnvironmentQuality management departments, compliance teamsProduction lines, testing labs
Industry UsageManufacturing, healthcare, aerospaceManufacturing, software, healthcare

While both roles focus on quality, the Quality Systems Manager primarily manages the overall quality management system and compliance, whereas the Quality Assurance Manager concentrates on product testing and ensuring quality during production. Understanding these differences helps in selecting the right career path or hiring the appropriate professional.

What is the salary for a quality manager?

The salary for a Quality Systems Manager typically ranges from $70,000 to $120,000 annually, depending on experience, industry, and location. Certifications such as ASQ CQE or ISO auditor can influence earning potential, and the role often requires strong knowledge of quality management systems like ISO 9001.

What Does a Quality Systems Manager Do?

As a quality systems manager, your primary responsibilities are monitoring the production processes and ensuring factory machinery/goods are within company and industry requirements. Your duties include weighing, sampling, or testing products for quality and functionality. You may also report the results of quality control tests. You monitor the equipment and people involved, and help with the development and implementation of improved management systems. You are also in charge of creating a standard operating procedure for the specific plant where you work. You check that everything is running at full efficiency and the quality of merchandise is standardized.

How does a Quality Systems Manager typically collaborate with cross-functional teams to drive continuous improvement?

A Quality Systems Manager works closely with departments such as manufacturing, engineering, regulatory, and supply chain to ensure that quality standards are consistently met and improved. They often lead or participate in cross-functional meetings to identify process gaps, analyze data, and develop corrective and preventive action plans. Effective communication and project management skills are essential, as the role involves aligning diverse teams toward common quality objectives and facilitating training or audits to support compliance and improvement initiatives.
More about Quality Systems Manager jobs
What are the most commonly searched types of Quality Systems jobs in Raleigh, NC? The most popular types of Quality Systems jobs in Raleigh, NC are:
What are popular job titles related to Quality Systems Manager jobs in Raleigh, NC? For Quality Systems Manager jobs in Raleigh, NC, the most frequently searched job titles are:
What job categories do people searching Quality Systems Manager jobs in Raleigh, NC look for? The top searched job categories for Quality Systems Manager jobs in Raleigh, NC are:
What cities near Raleigh, NC are hiring for Quality Systems Manager jobs? Cities near Raleigh, NC with the most Quality Systems Manager job openings:
Quality Systems Manager jobs near you
Infographic showing various Quality Systems Manager job openings in Raleigh, NC as of July 2026, with employment types broken down into 81% Full Time, 16% Part Time, 1% Temporary, and 2% Contract. Highlights an 86% Physical, 1% Hybrid, and 13% Remote job distribution, with an average salary of $95,855 per year, or $46.1 per hour.

Systems Manager, Digital Quality

Oxford Biomedica

Durham, NC • On-site

Other

Re-posted 5 hours ago

Job description

Join Us in Changing Lives

 

At OXB, our people are at the heart of everything we do. We're on a mission to enable life-changing therapies to reach patients around the world-and we're looking for passionate individuals who embody our core values every day: Responsible, Responsive, Resilient, and Respectful.

Following the expansion of our US footprint with the acquisition of a new commercial-scale viral vector facility in Durham, North Carolina we have some new opportunities to join us.

We're currently recruiting for a Manager, Digital Quality Systemsto join our Quality team. In this role, you will provide leadership and oversight for the quality and compliance of computerized and software systems, across all phases of the System Development Life Cycle. You willserve as the site Subject Matter Expert, for digital quality and data integrity, ensuring adherence to GxP requirements, corporate digital governance programs, and regulatory expectations, playing a key part in advancing our mission and making a real difference. 

Please note this is a full time role, based on site in Durham, NC.

Your responsibilities in this role would be:

    • Provide quality oversight for computerized and software systems, across the SDLC. 

    • Review and approve SDLC documentation, change controls, validation plans, URS, FRS, and related artifacts. 

    • Oversee deviations, CAPAs, and continuous improvement activities associated with computerized systems. 

    • Lead site initiatives to align, harmonize, and standardize digital systems governance with corporate programs (e.g., SDLC, Data Integrity, Risk Management, Periodic Reviews). 

    • Act as the site Data Integrity steward, ensuring adherence to Resilience's DI program and implementing DI controls for procured and in-house systems. 

    • Maintain all digital systems in a state of inspection readiness. 

    • Present and defend digital quality and data integrity programs and associated verification artifacts during client audits and regulatory inspections. 

    • Support internal audits, customer audits, and regulatory inspections. 

    • Provide guidance to SMEs and site stakeholders on maintaining compliant and inspection-ready digital systems. 

    • Serve as liaison between site functions (Tech Ops, QA, Validation) and central dQ/DI functions. 

    • Represent the site in quality leadership forums, site Quality Review Board, and corporate governance boards to adopt corporate digital quality and DI standards. 

    • Establish, monitor, and report on site-based dQ/DI KPIs to site and corporate leadership. 

    • Lead/assist with vendor audits and oversee risk-based digital system validation assessments. 

We are Looking For:

  • Bachelor's degree or higher in IT, Computer Systems, Life Sciences, Engineering, or a related field. 

  • Minimum of 5-7 years in the pharmaceutical/biotechnology industry, including IT compliance, digital quality, or computerized systems.

  • Hands-on experience implementing and managing GxP-compliant computerized system quality programs (COTS and custom systems). 

  • Demonstrated experience designing and enforcing data integrity controls in computerized systems. 

  • Experience managing high-performance teams and influencing cross-functional stakeholders. 

  • Familiarity with AI/ML, automation, and next-generation laboratory platforms is a plus. 

  • Comprehensive knowledge of global GMP regulations and guidance, including FDA, EU, ICH, GLP, GDocP, GDP, and GCP. 

  • Strong experience in reviewing and approving system life cycle documentation, validation plans, change controls, and other digital quality artifacts. 

 

This role does not offer sponsorship for work authorization. External applicants must be eligible to work in the United States.

 

About Us:

OXB is a quality and innovation-led viral vector CDMO with a mission to enable its clients to deliver life changing therapies to patients around the world. One of the original pioneers in cell and gene therapy, we have more than 30 years of experience in viral vectors; the driving force behind the majority of gene therapies.

OXB collaborates with some of the world's most innovative pharmaceutical and biotechnology companies, providing viral vector development and manufacturing expertise in lentivirus, adeno-associated virus (AAV) and adenoviral vectors. OXB's world-class capabilities span from early-stage development to commercialisation. These capabilities are supported by robust quality-assurance systems, analytical methods, and depth of regulatory expertise.

 

Why Join Us?

  •  Competitive total reward packages
  •  Wellbeing programs that support your mental and physical health
  •  Career development opportunities to help you grow and thrive
  •  Supportive, inclusive, and collaborative culture
  •  State-of-the-art labs and manufacturing facilities
  • A company that lives its values: Responsible, Responsive, Resilient,         Respect

We want you to feel inspired every day. At OXB, we're future-focused and growing fast. We succeed together-through passion, commitment, and teamwork.

Ready to Make a Difference?

 

 

Apply