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Python Junior Jobs in Charleston, SC (NOW HIRING)

Navstar

Software Engineer III

North Charleston, SC

$54.75 - $73.75/hr

Proficiency in Python and Java for AI/ML model development, data processing, and API ... Experience mentoring junior engineers and fostering best practices in AI/ML development, testing ...

CGI Inc.

Senior-Level Business Analyst

North Charleston, SC · On-site

$88K - $114K/yr

... SQL, Python, Java, HTML or CSS . Strong analytical problem solving skills. . Excellent ... Affinity for mentorship of junior members of the team to coach, peer review and assist with ...

Munich Re

Data Scientist, AI

Charleston, SC · On-site +1

Proficiency in statistical programming languages such as R, Python, SAS, or similar, alongside ... Mentor junior team members. * Data Scientist: 2 or more years of data science/predictive analytics ...

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Python Junior information

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$22.5K

$83.3K

$128.7K

How much do python junior jobs pay per year?

As of Jun 19, 2026, the average yearly pay for python junior in Charleston, SC is $83,265.00, according to ZipRecruiter salary data. Most workers in this role earn between $62,700.00 and $81,400.00 per year, depending on experience, location, and employer.

What are some common challenges faced by Python Junior developers during their first year on the job?

Python Junior developers often encounter challenges such as understanding large codebases, managing version control with tools like Git, and adapting to team workflows. They may also need to improve their debugging skills and learn to write clean, maintainable code that meets team standards. Regular communication with senior developers and proactively seeking feedback can help overcome these hurdles and accelerate professional growth.

What is the difference between Python Junior vs Python Developer?

AspectPython JuniorPython Developer
Required CredentialsBasic programming knowledge, often a diploma or bootcampMore experience, often a degree in CS or related field
Work EnvironmentEntry-level projects, supervised tasksFull project responsibilities, collaborative teams
Industry UsageInternships, junior roles in tech companiesMid-level roles across industries like finance, tech, healthcare

The main difference between a Python Junior and a Python Developer lies in experience and responsibilities. Python Juniors typically have basic skills and work under supervision, while Python Developers handle more complex tasks independently. Employers seek Python Juniors for entry-level positions, with opportunities to grow into full Python Developers as skills develop.

What are the key skills and qualifications needed to thrive as a Python Junior, and why are they important?

To thrive as a Python Junior, you need a good grasp of Python programming fundamentals, problem-solving abilities, and a relevant degree or coursework in computer science or a related field. Familiarity with version control systems like Git, code editors (e.g., VS Code), and basic understanding of frameworks such as Django or Flask is often expected. Strong communication, willingness to learn, and teamwork are important soft skills that set candidates apart. These skills and qualities are essential for effectively contributing to projects, collaborating with team members, and growing within a technical environment.

What are Python Juniors?

Python Juniors are entry-level software developers who specialize in using the Python programming language. They typically have foundational knowledge of Python and basic software development principles, and may work on tasks such as writing simple scripts, debugging code, or supporting more experienced developers on larger projects. Python Juniors are often recent graduates or individuals transitioning into software development, and their role offers opportunities to learn and grow their skills in real-world settings.
What are the most commonly searched types of Python jobs in Charleston, SC? The most popular types of Python jobs in Charleston, SC are:
What are popular job titles related to Python Junior jobs in Charleston, SC? For Python Junior jobs in Charleston, SC, the most frequently searched job titles are:
What job categories do people searching Python Junior jobs in Charleston, SC look for? The top searched job categories for Python Junior jobs in Charleston, SC are:
What cities near Charleston, SC are hiring for Python Junior jobs? Cities near Charleston, SC with the most Python Junior job openings:
Python Junior jobs near you
Infographic showing various Python Junior job openings in Charleston, SC as of June 2026, with employment types broken down into 100% Full Time. Highlights an 100% In-person job distribution, with an average salary of $83,265 per year, or $40 per hour.

UNIV - Open Rank Faculty - Department of Radiation Medicine

Medical University of South Carolina

Charleston, SC • On-site

Other

Posted 19 days ago

Job description

Job Description Summary
Bioinformatics Lead, ctDNA Sequencing & Translational Genomics
Location: Charleston, SC, Medical University of South Carolina (MUSC), (hybrid/remote may be considered for exceptional candidates)
Entity
Medical University of South Carolina (MUSC - Univ)
Worker Type
Employee
Worker Sub-Type
Faculty
Cost Center
CC001058 COM Radiation Oncology
Pay Rate Type
Salary
Pay Grade
University-00
Pay Range
0.00 - 0.00 - 0.000
Scheduled Weekly Hours
40
Work Shift
Job Description
Position Summary
We are recruiting a Bioinformatics Lead to build and continuously improve the computational analysis platform supporting high-sensitivity circulating tumor DNA (ctDNA) assay development and translational clinical research. This role will support NGS data processing, quality control frameworks, error suppression, variant detection, and reporting across tumor-informed and tumor-naïve workflows. The successful candidate will work closely with wet-lab scientists and clinicians to enable rapid iteration, reproducibility, and scalability, with an emphasis on ultra-low allele fraction detection and rigorous translational study support.
Key Responsibilities
Pipeline development and analysis support
  • Develop and maintain computational workflows supporting ctDNA-focused targeted sequencing analyses.
  • Implement robust quality control metrics, acceptance criteria, and failure triage processes for high-depth sequencing runs.
  • Generate analysis outputs and summaries to support translational studies, manuscripts, and grant applications.
  • Contribute to continuous improvement of analytic performance (sensitivity/specificity) for ultra-low VAF detection and MRD-related applications.
Translational collaboration
  • Partner with wet-lab and clinical teams to align assay design, sample processing, and analytic outputs; participate in troubleshooting and iterative optimization.
  • Support study design discussions, analytic endpoint definitions, and interpretation of results for translational research programs.
Data stewardship
  • Support best practices for data governance, provenance, documentation, and reproducibility in handling human genomic data.
  • Work with institutional resources to implement secure computational environments and appropriate data access practices.
Mentorship and program growth
  • Mentor junior analysts as the program grows; contribute to hiring, onboarding, and training as needed.
  • Help establish standards for analytic workflows, documentation, and communication across the research team.
Required Qualifications
  • PhD in Bioinformatics, Computational Biology, Genetics/Genomics, Computer Science, Biostatistics, or related field; or MS with substantial relevant experience (track/title commensurate with credentials).
  • Demonstrated experience analyzing ctDNA NGS data, including ultra-low allele fraction detection and/or MRD-related workflows.
  • Strong NGS fundamentals: alignment, variant calling, QC, annotation, and interpretation-ready output generation.
  • Proficiency in Python and/or R; strong comfort with Linux/Unix environments.
  • Experience implementing reproducible analytic workflows and maintaining code in collaborative environments (e.g., version control).
  • Track record of delivering robust pipelines used repeatedly for real datasets (not one-off scripts).
  • Strong communication skills and ability to operate effectively in a multidisciplinary translational environment.
Preferred Qualifications
Any of the following (or similar) would be a plus:
  • Method development experience related to error suppression, background error modeling, consensus approaches, or sensitivity/specificity benchmarking for ultra-low VAF detection.
  • Experience designing computational validation plans (e.g., precision/recall, LOD, reproducibility) and supporting assay/pipeline iteration.
  • Experience with FFPE tumor tissue sequencing analysis and variant calling (or similar challenging specimen types with artifact-aware calling and QC).
  • Familiarity with HIPAA-aligned compute environments and practices for handling human genomic data; experience with secure cloud environments (AWS/GCP/Azure).
  • Experience working in or alongside clinical genomics settings and documentation practices supportive of eventual clinical validation.
  • Experience mentoring analysts/engineers and/or leading pipeline development across multiple projects.
Application Instructions
Please submit:
  • CV
  • Brief cover letter describing ctDNA/NGS analysis experience and role-fit
  • (Optional) Link to code samples or repositories demonstrating relevant workflow/pipeline work
  • (Optional) Contact information for 3 references

Additional Job Description
Physical Requirements: (Note: The following descriptions are applicable to this section: Continuous - 6-8 hours per shift; Frequent - 2-6 hours per shift; Infrequent - 0-2 hours per shift) Ability to perform job functions in an upright position. (Frequent) Ability to perform job functions in a seated position. (Frequent) Ability to perform job functions while walking/mobile. (Frequent) Ability to work indoors. (Continuous) Ability to work outdoors in all weather and temperature extremes. (Infrequent) Ability to work in confined/cramped spaces. (Infrequent) Ability to perform job functions from kneeling positions. (Infrequent) Ability to squat and perform job functions. (Infrequent) Ability to perform 'pinching' operations. (Infrequent) Ability to fully use both hands/arms. (Frequent) Ability to perform repetitive motions with hands/wrists/elbows and shoulders. (Frequent) Ability to reach in all directions. (Frequent) Possess good finger dexterity. (Continuous) Ability to maintain tactile sensory functions. (Continuous) Ability to lift and carry 15 lbs., unassisted. (Infrequent) Ability to lift objects, up to 15 lbs., from floor level to height of 36 inches, unassisted. (Infrequent) Ability to lower objects, up to 15 lbs., from height of 36 inches to floor level, unassisted. (Infrequent) Ability to push/pull objects, up to 15 lbs., unassisted. (Infrequent) Ability to maintain 20/40 vision, corrected, in one eye or with both eyes. (Continuous) Ability to see and recognize objects close at hand. (Frequent) Ability to see and recognize objects at a distance. (Frequent) Ability to determine distance/relationship between objects; depth perception. (Continuous) Good peripheral vision capabilities. (Continuous) Ability to maintain hearing acuity, with correction. (Continuous) Ability to perform gross motor functions with frequent fine motor movements. (Frequent)
If you like working with energetic enthusiastic individuals, you will enjoy your career with us!
The Medical University of South Carolina is an Equal Opportunity Employer. MUSC does not discriminate on the basis of race, color, religion or belief, age, sex, national origin, gender identity, sexual orientation, disability, protected veteran status, family or parental status, or any other status protected by state laws and/or federal regulations. All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications, merit and business need.
Medical University of South Carolina participates in the federal E-Verify program to confirm the identity and employment authorization of all newly hired employees. For further information about the E-Verify program, please click here: http://www.uscis.gov/e-verify/employees

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