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Protein Engineer Jobs in Indiana (NOW HIRING)

Cargill

Waste Water Technician

Hammond, IN · On-site

$18.50 - $25.50/hr

Our portfolio includes poultry, beef, egg, alternative protein, salt, oils, starches, sweeteners ... Associates degree or higher in science, technology, chemistry, biology, engineering or math.

Cargill

Waste Water Technician

Hammond, IN · On-site

$18.50 - $25.50/hr

Our portfolio includes poultry, beef, egg, alternative protein, salt, oils, starches, sweeteners ... Associates degree or higher in science, technology, chemistry, biology, engineering or math.

Cargill

Waste Water Technician

Hammond, IN · On-site

$18.75 - $25.75/hr

Our portfolio includes poultry, beef, egg, alternative protein, salt, oils, starches, sweeteners ... Associates degree or higher in science, technology, chemistry, biology, engineering or math.

Specialty Foods Group

R&D Meat Scientist

Delphi, IN · On-site

Partner with Operations, Engineering, QA, Sales and Marketing, and Regulatory to translate business ... Strong understanding of meat functionality (protein bind, blending, water activity, cook loss ...

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Protein Engineer information

What are the typical daily tasks and projects for a Protein Engineer?

Protein Engineers typically spend their days designing and conducting experiments to modify and improve protein characteristics, analyzing data from assays, and collaborating with cross-functional teams such as molecular biologists and biochemists. Their work often involves using specialized laboratory equipment, computational modeling tools, and maintaining detailed records of their experimental results. Projects may include developing enzymes for industrial processes, optimizing therapeutic proteins, or engineering innovative biomaterials. The pace can be dynamic, with a mix of independent bench work and group meetings to discuss progress, troubleshoot challenges, and plan next steps. This collaborative environment offers opportunities to learn from peers and contribute to cutting-edge scientific advancements.

What are the key skills and qualifications needed to thrive in the Protein Engineer position, and why are they important?

To thrive as a Protein Engineer, you need expertise in molecular biology, biochemistry, and protein structure-function analysis, often supported by an advanced degree in a relevant scientific field. Familiarity with tools such as protein modeling software, high-throughput screening systems, and genetic engineering techniques is commonly required. Attention to detail, strong analytical thinking, and effective teamwork are valuable soft skills in this role. These abilities are crucial for designing, optimizing, and testing proteins with desired properties, ensuring impactful contributions to research or product development.

What does a Protein Engineer do?

A Protein Engineer designs and modifies proteins for specific functions in fields like medicine, biotechnology, and bioengineering. They use computational modeling, molecular biology techniques, and biochemical assays to improve protein stability, activity, or binding properties. Their work is crucial for developing new therapeutics, enzymes, and biomaterials for various industries.

What are the most commonly searched types of Protein Engineer jobs in Indiana? The most popular types of Protein Engineer jobs in Indiana are:
What are popular job titles related to Protein Engineer jobs in Indiana? For Protein Engineer jobs in Indiana, the most frequently searched job titles are:
What job categories do people searching Protein Engineer jobs in Indiana look for? The top searched job categories for Protein Engineer jobs in Indiana are:
Protein Engineer jobs near you
Senior Scientist, Downstream Process Development

Senior Scientist, Downstream Process Development

Elanco Animal Health Incorporated

Indianapolis, IN • On-site

$87K - $119K/yr

Full-time

Retirement, PTO

Posted 14 hours ago

Elanco rating

7.8

Company rating: 7.8 out of 10

Based on 25 frontline employees who took The Breakroom Quiz

44th of 74 rated pharmaceutical

Job description

At Elanco (NYSE: ELAN) - it all starts with animals!
As a global leader in animal health, we are dedicated to innovation and delivering products and services to prevent and treat disease in farm animals and pets. At Elanco, we are driven by our vision of Food and Companionship Enriching Life and our purpose - all to Go Beyond for Animals, Customers, Society and Our People.
At Elanco, we pride ourselves on fostering a diverse and inclusive work environment. We believe that diversity is the driving force behind innovation, creativity, and overall business success. Here, you'll be part of a company that values and champions new ways of thinking, work with dynamic individuals, and acquire new skills and experiences that will propel your career to new heights.
Making animals' lives better makes life better - join our team today!
Your Role: Senior Scientist, Downstream Process Development
Elanco is seeking a Senior Scientist, Downstream Process Development to lead purification process development for biologic drug substances, with a focus on monoclonal antibodies, therapeutic proteins, and mammalian cell culture-derived biologics.
This role will support programs from bench and pilot scale through process scale-up, technology transfer, process characterization, GMP manufacturing implementation, clinical material production, and CMC/regulatory filing support.
The ideal candidate will have hands-on experience developing and optimizing downstream purification processes, including chromatography and filtration-based unit operations such as Protein A or affinity chromatography, ion exchange chromatography, polishing steps, viral clearance or viral inactivation, depth filtration, UF/DF, TFF, and scale-down model development.
You will partner closely with R&D, TS/MS, Manufacturing, Quality, Supply Chain, Regulatory, and external CDMOs to ensure successful process transfer, implementation, and commercialization. This role requires strong technical judgment, clear communication, and the ability to lead cross-functional work in a fast-paced biologics development environment.
Your Responsibilities
  • Lead downstream process development for early- and late-stage biologic programs, including monoclonal antibodies, therapeutic proteins, and other biologic modalities.
  • Develop and optimize purification processes using phase-appropriate strategies, QbD principles, and process characterization approaches.
  • Design and execute bench- and pilot-scale studies, including scale-down model development, process scale-up, and manufacturing support.
  • Support risk assessments, control strategy development, stage-gate reviews, and technical decision-making for biologic drug substance programs.
  • Author and review technical reports, process development documents, tech transfer packages, and CMC source documents for regulatory submissions.
  • Support responses to CMC questions from regulatory agencies.
  • Partner with R&D, TS/MS, Manufacturing, Quality, Supply Chain, Regulatory, Launch Teams, and external CDMOs to ensure successful tech transfer, clinical material production, and commercialization.
  • Serve as a downstream process development subject matter expert for internal teams, manufacturing sites, and external partners.

What You Need to Succeed
  • MSc or PhD in chemistry, pharmaceutical sciences, biotechnology, chemical engineering, or a related scientific discipline. Equivalent experience may be considered.
  • PhD with 7+ years or MSc with 12+ years of experience in downstream biologics process development, preferably with mammalian cell culture-derived biologic products.
  • Hands-on experience developing and optimizing downstream purification processes for biologic drug substances, including monoclonal antibodies, therapeutic proteins, or other protein-based biologic modalities.
  • Experience supporting late-stage development, process scale-up, technology transfer, and implementation into GMP manufacturing.
  • Experience contributing to CMC/regulatory filing activities, including technical reports, source documents, process descriptions, tech transfer documents, or responses to regulatory agency questions.
  • Strong understanding of downstream unit operations such as chromatography, filtration, UF/DF, TFF, polishing steps, viral clearance or viral inactivation, process characterization, and scale-down model development.

What Will Give You a Competitive Edge
  • Strong understanding of GMP, Quality by Design, process characterization, control strategy development, and risk assessment principles.
  • Demonstrated success developing, scaling, transferring, or commercializing biologics, pharmaceuticals, vaccines, or other complex biological products.
  • Experience working with internal manufacturing teams, TS/MS, Quality, Regulatory, Supply Chain, Launch Teams, and external CDMOs.
  • Strong interpersonal and leadership skills, with the ability to influence stakeholders and lead cross-functional technical teams.
  • Ability to manage multiple priorities, navigate ambiguity, and communicate complex technical information through clear writing and presentations.
  • Experience with AI/ML applications in process development is a plus.
  • Animal health experience is advantageous but not required.

Additional Information:
  • Travel: 10-20% (domestic and international)
  • Location: Indianapolis, IN - Hybrid Work Environment

Elanco Benefits and Perks:
We offer a comprehensive benefits package focusing on financial, physical, and mental well-being while encouraging our employees to pursue our purpose! Some highlights include:
  • 8-week parental leave

  • 9 Employee Resource Groups

  • Annual bonus offering

  • Up to 6% 401K matching

Don't meet every single requirement? Studies have shown underrepresented groups are less likely to apply to jobs unless they meet every single qualification. At Elanco we are dedicated to building a diverse and inclusive work environment. If you think you might be a good fit for a role but don't necessarily meet every requirement, we encourage you to apply. You may be the right candidate for this role or other roles!
Elanco Benefits and Perks:
We offer a comprehensive benefits package focusing on financial, physical, and mental well-being while encouraging our employees to pursue our purpose! Some highlights include:
• Multiple relocation packages
• Two weeklong shutdowns (mid-summer and year-end) in the US (in addition to PTO)
• 8-week parental leave
• 9 Employee Resource Groups
• Annual bonus offering
• Flexible work arrangements
• Up to 6% 401K matching
Elanco is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status
Elanco may use automated tools, including AI, to support parts of our recruitment process, such as reviewing applications against job-related criteria and/or transferrable skills. These tools help ensure a consistent, structured evaluation, but they do not make hiring decisions. All decisions involve a human reviewer. For more information on how we handle personal data, please see our Elanco Workforce Privacy Notice.
Elanco is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status
Elanco may use automated tools, including AI, to support parts of our recruitment process, such as reviewing applications against job-related criteria and/or transferrable skills. These tools help ensure a consistent, structured evaluation, but they do not make hiring decisions. All decisions involve a human reviewer. For more information on how we handle personal data, please see our Elanco Workforce Privacy Notice.

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