Apply generative AI and structural modeling techniques to design novel antibody and protein modalities from scratch, optimizing them for high-precision epitope targeting, affinity, and specificity.
Apply generative AI and structural modeling techniques to design novel antibody and protein modalities from scratch, optimizing them for high-precision epitope targeting, affinity, and specificity.
Post-doctoral Computational Chemist, Advanced Molecular Design
Indianapolis, IN · On-site
$21 - $28.25/hr
... protein-protein interactions in support of structure-based drug design. * Build and maintain ... informatic infrastructure enabling broad utilization of quantum mechanics, molecular dynamics, and ...
Post-doctoral Computational Chemist, Advanced Molecular Design
Indianapolis, IN · On-site
$21 - $28.25/hr
... protein-protein interactions in support of structure-based drug design. * Build and maintain ... informatic infrastructure enabling broad utilization of quantum mechanics, molecular dynamics, and ...
Post-doctoral Computational Chemist, Advanced Molecular Design
Indianapolis, IN · On-site
$21 - $28.25/hr
... protein-protein interactions in support of structure-based drug design. * Build and maintain ... informatic infrastructure enabling broad utilization of quantum mechanics, molecular dynamics, and ...
Post-doctoral Computational Chemist, Advanced Molecular Design
Indianapolis, IN · On-site
$21 - $28.25/hr
... protein-protein interactions in support of structure-based drug design. * Build and maintain ... informatic infrastructure enabling broad utilization of quantum mechanics, molecular dynamics, and ...
Senior Research Scientist
Indianapolis, IN · On-site
$94K - $120K/yr
Experience with generative AI (e.g., ProteinMPNN) for de novo protein design and affinity maturation. * Demonstrated ability to lead projects in a fast-paced, agile environment; ability to ...
New
Senior Research Scientist
Indianapolis, IN · On-site
$94K - $120K/yr
Experience with generative AI (e.g., ProteinMPNN) for de novo protein design and affinity maturation. * Demonstrated ability to lead projects in a fast-paced, agile environment; ability to ...
New
The individual will partner with a multidisciplinary team to design, develop, and implement machine ... Assess potential mechanisms of toxicity by assessing ligand-protein binding affinity using protein ...
Quick apply
The individual will partner with a multidisciplinary team to design, develop, and implement machine ... Assess potential mechanisms of toxicity by assessing ligand-protein binding affinity using protein ...
Post-Doctoral Scientist - Formulations Bioproduct Research & Development - FDE
Indianapolis, IN · On-site
... design. * Collaborate closely with cross-functional teamsacross drugsubstance, drugproduct ... Develop deepexpertisein protein biophysics, structural biology, formulation science, and ...
Post-Doctoral Scientist - Formulations Bioproduct Research & Development - FDE
Indianapolis, IN · On-site
... design. * Collaborate closely with cross-functional teamsacross drugsubstance, drugproduct ... Develop deepexpertisein protein biophysics, structural biology, formulation science, and ...
Post-Doctoral Scientist - Formulations Bioproduct Research & Development - FDE
Indianapolis, IN · On-site
... design. * Collaborate closely with cross-functional teams across drug substance, drug product ... Develop deep expertise in protein biophysics, structural biology, formulation science, and ...
Post-Doctoral Scientist - Formulations Bioproduct Research & Development - FDE
Indianapolis, IN · On-site
... design. * Collaborate closely with cross-functional teams across drug substance, drug product ... Develop deep expertise in protein biophysics, structural biology, formulation science, and ...
... protein-protein interactions in support of structure-based drug design. * Develop and implement novel AI and neural networks for analyzing experimental and molecular dynamics simulations into ...
... protein-protein interactions in support of structure-based drug design. * Develop and implement novel AI and neural networks for analyzing experimental and molecular dynamics simulations into ...
... protein-protein interactions in support of structure-based drug design. * Develop and implement novel AI and neural networks for analyzing experimental and molecular dynamics simulations into ...
... protein-protein interactions in support of structure-based drug design. * Develop and implement novel AI and neural networks for analyzing experimental and molecular dynamics simulations into ...
Lead formulation programs for lead molecules, applying deepexpertisein protein chemistry and ... Experience using Design of Experiments (DoE) and statistical analysis (e.g., JMP ...
Lead formulation programs for lead molecules, applying deepexpertisein protein chemistry and ... Experience using Design of Experiments (DoE) and statistical analysis (e.g., JMP ...
Lead formulation programs for lead molecules, applying deep expertise in protein chemistry and ... Experience using Design of Experiments (DoE) and statistical analysis (e.g., JMP) to optimize ...
Lead formulation programs for lead molecules, applying deep expertise in protein chemistry and ... Experience using Design of Experiments (DoE) and statistical analysis (e.g., JMP) to optimize ...
Director, Vaccine Formulation Development
Indianapolis, IN · On-site
$177 - $281.60/hr
Lead others in the design, execution and interpretation of experiments to drive the definition and ... protein/subunit vaccines, bacterial vaccine platforms, and antigen‑display nanoparticles.
Director, Vaccine Formulation Development
Indianapolis, IN · On-site
$177 - $281.60/hr
Lead others in the design, execution and interpretation of experiments to drive the definition and ... protein/subunit vaccines, bacterial vaccine platforms, and antigen‑display nanoparticles.
Apply generative AI and structural modeling techniques to design novel antibody and protein modalities from scratch, optimizing them for high-precision epitope targeting, affinity, and specificity.
Apply generative AI and structural modeling techniques to design novel antibody and protein modalities from scratch, optimizing them for high-precision epitope targeting, affinity, and specificity.
... protein antigens, emulsion- or aluminum-based co-formulated vaccines. * Support the drug product ... Lead others in the design, execution and interpretation of experiments to drive the definition and ...
... protein antigens, emulsion- or aluminum-based co-formulated vaccines. * Support the drug product ... Lead others in the design, execution and interpretation of experiments to drive the definition and ...
... protein antigens, emulsion- or aluminum-based co-formulated vaccines. * Support the drug product ... Lead others in the design, execution and interpretation of experiments to drive the definition and ...
... protein antigens, emulsion- or aluminum-based co-formulated vaccines. * Support the drug product ... Lead others in the design, execution and interpretation of experiments to drive the definition and ...
Senior Scientist, Downstream Process Development
Indianapolis, IN · On-site
$87K - $119K/yr
... as Protein A or affinity chromatography, ion exchange chromatography, polishing steps, viral ... Design and execute bench- and pilot-scale studies, including scale-down model development, process ...
Senior Scientist, Downstream Process Development
Indianapolis, IN · On-site
$87K - $119K/yr
... as Protein A or affinity chromatography, ion exchange chromatography, polishing steps, viral ... Design and execute bench- and pilot-scale studies, including scale-down model development, process ...
Senior Scientist, Downstream Process Development
Indianapolis, IN · On-site
$87K - $119K/yr
... as Protein A or affinity chromatography, ion exchange chromatography, polishing steps, viral ... Design and execute bench- and pilot-scale studies, including scale-down model development, process ...
Senior Scientist, Downstream Process Development
Indianapolis, IN · On-site
$87K - $119K/yr
... as Protein A or affinity chromatography, ion exchange chromatography, polishing steps, viral ... Design and execute bench- and pilot-scale studies, including scale-down model development, process ...
Biochemistry Tutor
Bloomington, IN · Remote
$18 - $40/hr
... protein purification strategies, and interpreting gel electrophoresis results. Emphasizes molecular-level reasoning and connects biochemistry to drug design, clinical diagnostics, and genetic disease ...
Biochemistry Tutor
Bloomington, IN · Remote
$18 - $40/hr
... protein purification strategies, and interpreting gel electrophoresis results. Emphasizes molecular-level reasoning and connects biochemistry to drug design, clinical diagnostics, and genetic disease ...
Biochemistry Tutor
Fort Wayne, IN · Remote
$18 - $40/hr
... protein purification strategies, and interpreting gel electrophoresis results. Emphasizes molecular-level reasoning and connects biochemistry to drug design, clinical diagnostics, and genetic disease ...
Biochemistry Tutor
Fort Wayne, IN · Remote
$18 - $40/hr
... protein purification strategies, and interpreting gel electrophoresis results. Emphasizes molecular-level reasoning and connects biochemistry to drug design, clinical diagnostics, and genetic disease ...
Biochemistry Tutor
West Lafayette, IN · Remote
$18 - $40/hr
... protein purification strategies, and interpreting gel electrophoresis results. Emphasizes molecular-level reasoning and connects biochemistry to drug design, clinical diagnostics, and genetic disease ...
Biochemistry Tutor
West Lafayette, IN · Remote
$18 - $40/hr
... protein purification strategies, and interpreting gel electrophoresis results. Emphasizes molecular-level reasoning and connects biochemistry to drug design, clinical diagnostics, and genetic disease ...
Protein Design information
What is the difference between Protein Design vs Protein Engineering?
| Aspect | Protein Design | Protein Engineering |
|---|---|---|
| Required Credentials | Biochemistry, Molecular Biology, Bioinformatics | Biochemistry, Molecular Biology, Bioinformatics |
| Work Environment | Research labs, biotech companies, academia | Research labs, biotech companies, academia |
| Industry Usage | Designing novel proteins, drug development, synthetic biology | Modifying existing proteins for improved function or stability |
Protein Design focuses on creating new proteins with specific functions, often using computational methods. Protein Engineering involves modifying existing proteins to enhance or alter their properties. Both roles require similar skills and are used in research, biotech, and pharmaceutical industries, but their goals differ: one designs from scratch, the other optimizes existing proteins.
What are some typical challenges faced by professionals in protein design, and how are they addressed within a team setting?
Professionals in protein design often encounter challenges such as predicting accurate protein folding, ensuring stability, and achieving desired biological activity. These complexities are typically addressed through close collaboration with computational biologists, structural biologists, and experimental scientists. Teams frequently hold cross-functional meetings to troubleshoot issues, share findings, and iterate on design strategies based on laboratory results. This collaborative environment helps leverage diverse expertise and accelerates the development of novel proteins with desired functions.
What are the key skills and qualifications needed to thrive as a protein design scientist, and why are they important?
To thrive as a Protein Design Scientist, you need a strong background in molecular biology, biochemistry, and computational modeling, typically supported by an advanced degree in a relevant field. Proficiency with tools such as Rosetta, PyMOL, and molecular dynamics simulation software, as well as experience with protein expression and purification techniques, is essential. Analytical thinking, problem-solving, and effective communication are important soft skills to drive innovation and collaborate with interdisciplinary teams. These skills are crucial for designing functional proteins, troubleshooting experiments, and advancing research goals in biotechnology and pharmaceutical development.
What is protein design?
Protein design is the process of creating new proteins or modifying existing ones to have specific functions or properties. This can involve using computational tools, laboratory techniques, or a combination of both to predict and engineer amino acid sequences that will fold into desired three-dimensional structures. Protein design is used in various fields, including medicine, biotechnology, and research, to develop novel enzymes, therapeutics, or materials. The field requires a strong understanding of biology, chemistry, and computer science to achieve successful outcomes.
What are popular job titles related to Protein Design jobs in Indiana? For Protein Design jobs in Indiana, the most frequently searched job titles are:
- Internship Protein Purification Scientist
- Senior Formulation Scientist
- Contract Research Scientist Biochemistry
- Antibody Drug Conjugate
- Freelance Assay Development Scientist
- Senior Membrane Scientist
- Day Economist Data Scientist
- Contract Protein Engineering Scientist
- Phd Scientist Mass Spectrometry
- Protein Scientist
What job categories do people searching Protein Design jobs in Indiana look for? The top searched job categories for Protein Design jobs in Indiana are:
What cities in Indiana are hiring for Protein Design jobs? Cities in Indiana with the most Protein Design job openings:
Research Scientist - Computational Biologist
Indianapolis, IN • On-site
Full-time
Retirement, PTO
Posted 6 days ago
Elanco rating
7.8
Based on 25 frontline employees who took The Breakroom Quiz
50th of 86 rated pharmaceutical
Job description
At Elanco (NYSE: ELAN) - it all starts with animals!
As a global leader in animal health, we are dedicated to innovation and delivering products and services to prevent and treat disease in farm animals and pets. At Elanco, we are driven by our vision of Food and Companionship Enriching Life and our purpose - all to Go Beyond for Animals, Customers, Society and Our People.
At Elanco, we pride ourselves on fostering a diverse and inclusive work environment. We believe that diversity is the driving force behind innovation, creativity, and overall business success. Here, you'll be part of a company that values and champions new ways of thinking, work with dynamic individuals, and acquire new skills and experiences that will propel your career to new heights.
Making animals' lives better makes life better - join our team today!
Your Role: Research Scientist - Computational Biologist
As a Research Scientist on our Discovery Research team, you will be at the forefront of Elanco's mission to deliver innovative biologics that improve animal health. You will leverage and develop state-of-the-art AI and structural modeling tools to predict, design, and optimize therapeutic antibodies and proteins. Partnering closely with our principal Computational Scientist and wet-lab teams, you will directly impact the speed and success of our pipeline, helping to create the next generation of animal health therapies. This role offers a unique opportunity to grow your skills in a rapidly evolving field while contributing to tangible, real-world outcomes.
Your Responsibilities:
What You Need to Succeed (minimum qualifications):
What will give you a strong edge (preferred qualifications):
Additional Information:
Don't meet every single requirement? Studies have shown underrecognized groups are less likely to apply to jobs unless they meet every single qualification. At Elanco we are dedicated to building a diverse and inclusive work environment. If you think you might be a good fit for a role but don't necessarily meet every requirement, we encourage you to apply. You may be the right candidate for this role or other roles!
Elanco Benefits and Perks:
We offer a comprehensive benefits package focusing on financial, physical, and mental well-being while encouraging our employees to pursue our purpose! Some highlights include:
Elanco is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status
Elanco may use automated tools, including AI, to support parts of our recruitment process, such as reviewing applications against job-related criteria and/or transferrable skills. These tools help ensure a consistent, structured evaluation, but they do not make hiring decisions. All decisions involve a human reviewer. For more information on how we handle personal data, please see our Elanco Workforce Privacy Notice.
As a global leader in animal health, we are dedicated to innovation and delivering products and services to prevent and treat disease in farm animals and pets. At Elanco, we are driven by our vision of Food and Companionship Enriching Life and our purpose - all to Go Beyond for Animals, Customers, Society and Our People.
At Elanco, we pride ourselves on fostering a diverse and inclusive work environment. We believe that diversity is the driving force behind innovation, creativity, and overall business success. Here, you'll be part of a company that values and champions new ways of thinking, work with dynamic individuals, and acquire new skills and experiences that will propel your career to new heights.
Making animals' lives better makes life better - join our team today!
Your Role: Research Scientist - Computational Biologist
As a Research Scientist on our Discovery Research team, you will be at the forefront of Elanco's mission to deliver innovative biologics that improve animal health. You will leverage and develop state-of-the-art AI and structural modeling tools to predict, design, and optimize therapeutic antibodies and proteins. Partnering closely with our principal Computational Scientist and wet-lab teams, you will directly impact the speed and success of our pipeline, helping to create the next generation of animal health therapies. This role offers a unique opportunity to grow your skills in a rapidly evolving field while contributing to tangible, real-world outcomes.
Your Responsibilities:
- Utilize and develop AI-driven tools (e.g., AlphaFold, Rosetta) to predict and design high-resolution structures of antibodies and other proteins, directly supporting our therapeutic biologics pipeline.
- Apply generative AI and structural modeling techniques to design novel antibody and protein modalities from scratch, optimizing them for high-precision epitope targeting, affinity, and specificity.
- Proactively identify and engineer out potential liabilities (e.g., aggregation, immunogenicity) and train novel structure-based ML architectures to enhance the developability of our biologic candidates.
- Partner closely with wet-lab scientists to analyze experimental data, validate computational predictions, and rapidly iterate on designs to accelerate antibody selection and optimization.
- Stay current with the evolving AI landscape by evaluating new tools, maintaining thorough documentation, and effectively communicating complex findings to cross-functional teams.
What You Need to Succeed (minimum qualifications):
- Education: Ph.D. in Computational Biology, Bioinformatics, Structural Biology, Computer Science, or a related field.
- Experience: 0-3 years of post-graduate experience applying computational methods to biological problems.
- Top Skills: A strong foundation in structural bioinformatics and AI/ML modeling, with proficiency in a programming language like Python, and the communication skills to work effectively in a cross-functional scientific environment.
What will give you a strong edge (preferred qualifications):
- Experience with de novo protein design tools, such as diffusion models or physics-based approaches.
- A track record of applying computational tools to solve biological problems, evidenced by publications or significant project contributions.
- Familiarity with cloud computing environments (e.g., AWS, GCP) and MLOps principles.
- Experience in antibody or protein engineering and a foundational understanding of immunology.
- A proactive mindset with a passion for staying current with the rapidly evolving AI landscape and a motivation to test and evaluate new methodologies.
Additional Information:
- Travel: Minimal
- Location: Global Elanco Headquarters - Indianapolis, IN - Hybrid Work Environment
Don't meet every single requirement? Studies have shown underrecognized groups are less likely to apply to jobs unless they meet every single qualification. At Elanco we are dedicated to building a diverse and inclusive work environment. If you think you might be a good fit for a role but don't necessarily meet every requirement, we encourage you to apply. You may be the right candidate for this role or other roles!
Elanco Benefits and Perks:
We offer a comprehensive benefits package focusing on financial, physical, and mental well-being while encouraging our employees to pursue our purpose! Some highlights include:
- Multiple relocation packages
- Two weeklong shutdowns (mid-summer and year-end) in the US (in addition to PTO)
- 8-week parental leave
- 9 Employee Resource Groups
- Annual bonus offering
- Flexible work arrangements
- Up to 6% 401K matching
Elanco is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status
Elanco may use automated tools, including AI, to support parts of our recruitment process, such as reviewing applications against job-related criteria and/or transferrable skills. These tools help ensure a consistent, structured evaluation, but they do not make hiring decisions. All decisions involve a human reviewer. For more information on how we handle personal data, please see our Elanco Workforce Privacy Notice.
About Elanco
Sourced by ZipRecruiter
Industry
Pharmaceutical and medicine manufacturing
Company size
5,001 - 10,000 Employees
Headquarters location
Greenfield, IN, US
Year founded
1954