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Postdoctoral In Yeast Genetics Jobs in Minnesota

Staff Laboratory is seeking a highly motivated Postdoctoral Fellow to investigate the cellular and ... D., or equivalent doctoral degree in neuroscience, cell biology, bioengineering, genetics, or ...

Staff Laboratory is seeking a highly motivated Postdoctoral Fellow to investigate the cellular and ... D., or equivalent doctoral degree in neuroscience, cell biology, bioengineering, genetics, or ...

Staff Laboratory is seeking a highly motivated Postdoctoral Fellow to investigate the cellular and ... D., or equivalent doctoral degree in neuroscience, cell biology, bioengineering, genetics, or ...

Research Fellow-Genomics

Rochester, MN · On-site

$64K - $74K/yr

Why Mayo Clinic Mayo Clinic is top-ranked in more specialties than any other care provider ... These projects involve a broad array of well-established techniques such as mouse genetics, CRISPR ...

... postdoctoral trainee with aspirations to become an independent scientist in academia or industry ... Our research focuses on neurovascular signaling, utilizing mouse genetics, molecular and protein ...

... year postdoctoral fellowship in pediatric neuropsychology o Licensed or license-eligible in ... ADHD, autism, learning disabilities, genetic or other medical conditions impacting development) o ...

Showing results 21-40

Postdoctoral In Yeast Genetics information

What is a postdoctoral in yeast genetics?

A Postdoctoral in Yeast Genetics is a researcher who has completed their doctoral studies (Ph.D.) and is engaging in advanced training and research specifically focused on the genetics of yeast. These scientists conduct experiments to understand genetic mechanisms, gene expression, and cellular processes in yeast, which is a widely used model organism in molecular biology. Their work can contribute to advancements in biotechnology, medicine, and basic science. Postdocs in this field often work in academic, government, or industrial labs, collaborating on research projects and publishing their findings.

What are the key skills and qualifications needed to thrive as a postdoctoral in yeast genetics?

To thrive as a Postdoctoral Researcher in Yeast Genetics, you need a Ph.D. in genetics, molecular biology, or a related field, along with expertise in yeast genetics techniques such as gene editing, transformation, and phenotypic analysis. Familiarity with molecular biology tools (PCR, CRISPR, next-generation sequencing), laboratory information management systems (LIMS), and bioinformatics platforms is typically required. Strong problem-solving abilities, communication skills, and the capacity to work collaboratively make candidates stand out in this role. These skills and qualities are essential for conducting innovative research, efficiently analyzing data, and contributing effectively to scientific teams.

What are some common challenges faced by postdoctoral researchers in yeast genetics, and how can they be addressed?

Postdoctoral researchers in yeast genetics often encounter challenges such as troubleshooting complex experimental protocols, managing large datasets from genomic or transcriptomic studies, and balancing independent research with collaborative projects. Navigating the rapid pace of technological advances can also be demanding. These challenges can be addressed by actively participating in lab meetings, seeking mentorship from senior scientists, and staying updated with current literature and methodologies. Building strong communication skills and collaborating closely with bioinformaticians and other specialists can also help overcome technical and analytical hurdles.

What are popular job titles related to Postdoctoral In Yeast Genetics jobs in Minnesota?

For Postdoctoral In Yeast Genetics jobs in Minnesota, the most frequently searched job titles are:

What job categories do people searching Postdoctoral In Yeast Genetics jobs in Minnesota look for?

The top searched job categories for Postdoctoral In Yeast Genetics jobs in Minnesota are:

Research Fellow - Neurology - Cousin lab

Mayo Clinic

Rochester, MN • On-site

Full-time

Medical, Dental, Vision, Retirement

Posted 29 days ago


Mayo Clinic rating

7.8

Company rating: 7.8 out of 10

Based on 699 frontline employees who took The Breakroom Quiz

128th of 887 rated healthcare providers


Job description


The Cousin Lab at Mayo Clinic is seeking a postdoctoral fellow will contribute to a growing rare disease therapeutics program with an initial emphasis on POLR2A-related disorders. This work will also support broader efforts in the lab, including genetic forms of ALS and other monogenic neurologic conditions. Projects may include iPSC-derived neural models, variant-mechanism studies, RNA-targeted therapies, genome editing, sequencing-based biomarkers, and collaboration with Mayo Clinic precision medicine and N-of-1 therapeutic programs, core facilities, and external academic partners.
The Cousin Lab at Mayo Clinic develops mechanism-guided, gene-targeted therapeutic strategies for rare neurogenetic diseases. Our work integrates clinical genetics, patient-derived biospecimens, functional genomics, iPSC-based disease modeling, preclinical therapeutic testing, and clinical translation.
Position Overview
The fellow will lead experimental and analytical components of translational rare disease projects. The role includes developing and characterizing patient-derived and engineered cell models; defining variant effects and disease mechanisms; designing and evaluating RNA-targeted and gene-editing therapeutic strategies; and integrating functional, genomic, and clinical data to prioritize treatment approaches. The position involves substantial wet-lab research, quantitative data analysis, manuscript and grant preparation, and cross-disciplinary collaboration.
The fellow will join a collaborative Mayo Clinic environment with access to clinical expertise, core facilities, genomic and sequencing resources, translational infrastructure, and multi-institutional rare disease networks. This position offers the opportunity to develop an independent research niche at the interface of rare disease biology, human neural modeling, and targeted therapeutic development; publish first-author manuscripts; present at national and international meetings; and pursue external fellowship or career-development funding.
Key Responsibilities
  • Disease Modeling & Assay Development: Develop and characterize patient-derived and engineered disease models, including fibroblasts, iPSCs, isogenic controls, iPSC-derived neural cell types, and organoid or multicellular systems.
  • Mechanistic & Functional Studies: Design and execute molecular, cellular, imaging, electrophysiologic, and functional genomics assays to define variant effects, disease mechanisms, cellular phenotypes, biomarkers, and therapeutic response.
  • Therapeutic Development: Develop and evaluate RNA-targeted and gene-editing strategies, including ASO/siRNA, allele-selective or splice-modifying approaches, CRISPR/base-editing platforms, delivery systems, and target-engagement or rescue assays.
  • Genomic Data Integration: Integrate variant interpretation, sequencing data, and functional readouts to prioritize therapeutic strategies and evaluate loss-of-function, dominant-negative, allele-specific, and related mechanisms.
  • Collaboration & Translation: Coordinate with the PI, clinicians, partners, core facilities, biobanks, and external collaborators to align patient samples, disease models, assays, and preclinical workflows.
  • Scientific Communication & Mentorship: Manage projects with rigor and reproducibility; prepare figures, reports, manuscripts, presentations, and grant/fellowship applications; and contribute to mentoring junior team members.

Qualifications
  • Education: Ph.D., M.D./Ph.D., or equivalent doctoral degree in neuroscience, genetics/genomics, molecular or cell biology, stem cell biology, biomedical engineering, pharmacology, RNA biology, bioengineering, or a related field.
  • Research Expertise: Demonstrated productivity in cell-based disease modeling, molecular biology, functional genomics, therapeutic development, neurogenetics, or rare disease biology.
  • Technical Skills: Strong wet-lab skills in aseptic cell culture, molecular biology, assay development, sequencing workflows, microscopy/imaging, and experimental documentation.
  • Quantitative & Analytical Skills: Ability to analyze, interpret, and communicate complex data; familiarity with Prism, R, Python, or related statistical and visualization tools is helpful.
  • Professional Skills: Excellent organization, independence, attention to detail, and communication skills, with the ability to thrive in a collaborative translational research environment.

Experience in one or more of the following areas is preferred:
  • iPSC & Neural Models: Experience with human iPSC culture, genome-edited/isogenic lines, neural differentiation, neurons, glia, organoids, or related iPSC-derived neural models.
  • Therapeutic Platforms: Experience with RNA-targeted therapeutic development, genome engineering, or delivery platforms, including ASOs, siRNA, CRISPR/Cas, base or prime editing, AAV, or LNPs.
  • Rare Disease Translation: Experience with rare genetic, neurodevelopmental, or neuromuscular disease models; patient-derived biospecimens; variant interpretation; genotype-phenotype analysis; or individualized/N-of-1 therapeutic approaches.
  • Genomics & Biomarkers: Experience with RNA-seq, long-read sequencing, phasing/haplotype analysis, single-cell or multi-omic workflows, biomarker discovery, bioinformatics, or high-content/high-throughput screening.
  • Scientific Leadership: Experience in translational or preclinical research, collaborative project management, manuscript preparation, grant writing, and mentoring.

Candidates should submit a CV, a brief cover letter describing research interests and relevant experience and contact information for 2-3 references.
About Us
Why Mayo Clinic
Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans - to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.
Benefits Highlights
  • Medical: Multiple plan options.
  • Dental: Delta Dental or reimbursement account for flexible coverage.
  • Vision: Affordable plan with national network.
  • Pre-Tax Savings: HSA and FSAs for eligible expenses.
  • Retirement: Competitive retirement package to secure your future.

About the Team
Just as our reputation has spread beyond our Minnesota roots, so have our locations. Today, our employees are located at our three major campuses in Phoenix/Scottsdale, Arizona, Jacksonville, Florida, Rochester, Minnesota, and at Mayo Clinic Health System campuses throughout Midwestern communities, and at our international locations. Each Mayo Clinic location is a special place where our employees thrive in both their work and personal lives. Learn more about what each unique Mayo Clinic campus has to offer, and where your best fit is.
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All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the "EOE is the Law". Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.

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Mayo Clinic is the largest integrated, not-for-profit medical group practice in the world. We're building the future, one where the best possible care is available to everyone — and more people can heal at home. Our relentless research turns into earlier diagnoses and new cures. That's how we inspire hope in those who need it most. At Mayo Clinic, experts work together to solve the most challenging unmet needs of patients. Our history of innovation dates back almost 150 years, when brothers Will and Charlie Mayo pioneered an integrated, team-based approach to medicine. Today, that trailblazing spirit drives innovations like Mayo Clinic Platform — which powers new technologies to change how care is delivered to all.

Industry

Hospitals

Company size

10,000+ Employees

Headquarters location

Rochester, MN, US

Year founded

1919