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Postdoc Python Jobs in Chicago, IL (NOW HIRING)

Postdoctoral Scholar

Evanston, IL ยท On-site

$61K - $68K/yr

Bioinformatics skills: use of R (or python) to analyze gene expression, single-cell and mutation analysis Minimum Competencies: (Skills, knowledge, and abilities.) * Strong problem-solving and ...

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Postdoc Python information

See Chicago, IL salary details

$13

$60

$88

How much do postdoc python jobs pay per hour?

As of Jul 21, 2026, the average hourly pay for postdoc python in Chicago, IL is $60.39, according to ZipRecruiter salary data. Most workers in this role earn between $49.76 and $68.61 per hour, depending on experience, location, and employer.

What are some common challenges postdoctoral researchers face when working with Python in academic research?

Postdoctoral researchers using Python often encounter challenges such as integrating Python with legacy codebases written in other languages, managing complex dependencies and environments, and ensuring reproducibility of research results. Collaborating with interdisciplinary teams may also require adapting code for different data formats and computational needs. Staying up-to-date with the latest Python libraries and best practices is crucial, as is documenting code so that it can be easily understood and used by other researchers.

What does a Postdoc Python do?

A Postdoc Python is a postdoctoral researcher who specializes in using the Python programming language for scientific research, data analysis, or software development. They typically work in academic or research settings, contributing to ongoing projects, developing computational tools, and publishing their findings. Their work may involve collaborating with other scientists, mentoring students, and advancing research through innovative coding and data analysis techniques. Proficiency in Python allows them to tackle complex problems in fields like bioinformatics, physics, engineering, and more.

What are the key skills and qualifications needed to thrive as a Postdoc Python, and why are they important?

To thrive as a Postdoc Python, you need a PhD in a relevant field, strong research experience, and advanced proficiency in Python programming. Familiarity with data analysis libraries (like NumPy, pandas, and SciPy), version control systems (such as Git), and computational tools is typically required. Critical thinking, problem-solving, and effective communication help differentiate outstanding candidates in collaborative and interdisciplinary environments. These skills ensure that complex research projects are executed efficiently, reproducibly, and with meaningful scientific contributions.

What is the difference between Postdoc Python vs Data Scientist?

AspectPostdoc PythonData Scientist
Required CredentialsPhD or equivalent in relevant field, strong Python skillsBachelor's or Master's in Data Science, Computer Science, or related field; Python skills often required
Work EnvironmentAcademic or research institutions, labsCorporate, tech companies, consulting firms
Industry UsageResearch projects, academic publicationsBusiness analytics, product development, data-driven decision making
Common Search/ComparisonPostdoc Python vs Data Scientist

While both roles require strong Python skills, a Postdoc Python typically focuses on research and academic projects, often requiring a PhD. In contrast, a Data Scientist applies Python in industry settings to analyze data, build models, and support business goals. The work environment and career paths differ, with Postdocs leaning toward academia and Data Scientists toward industry roles.

What cities near Chicago, IL are hiring for Postdoc Python jobs? Cities near Chicago, IL with the most Postdoc Python job openings:

Postdoctoral Fellow, Multimodal Modeling

Biohub

Chicago, IL โ€ข On-site

$84K/yr

Full-time

Retirement, PTO

Posted 5 days ago


Job description

Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We're building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere.
The Team
Our decoding inflammation team builds tools to enable precise molecular-level measurements of inflammation within human tissues in real time, and develop proactive, early interventions that can be deployed when inflammation - which underlies the most significant causes of death worldwide - first flares in the body. You can learn more about our work here.
Our team collaborates with three powerhouse universities - Northwestern University, the University of Chicago, and the University of Illinois Urbana-Champaign - to develop first-in-class technologies and make breakthroughs.
Our Vision
  • Pursue large scientific challenges that cannot be pursued in conventional environments
  • Enable individual investigators to pursue their riskiest and most innovative ideas
  • Facilitate research by scientists and clinicians at our home institutions and beyond

We are a team of passionate individuals powered by technology, guided by scientific research, and driven by collaboration, working toward a mission to cure or prevent all disease.
The Opportunity
The Chan Zuckerberg Biohub Chicago is seeking outstanding early-career scientists to join and participate in the launch of the Proteoform Spatial Biology Group by continuing their training as a Postdoctoral Fellow in Multimodal Modeling. The Proteoform Spatial Biology Group aims to uncover the spatiotemporal regulation of proteins and their unique molecular forms, proteoforms, in inflammation and autoimmunity. For this position, the ideal candidate is expected to have experience in working with multimodal and multiscale modeling of diverse datatypes across confocal microscopy images, mass spectrometry-based proteomics, phosphoproteomics, and/or interactomics.
What You'll Do
  • Design and train self-supervised multimodal models that fuse confocal protein imaging, single-cell protein proximity networks, and mass spectrometry-based phosphoproteomics into shared representations, using objectives such as reconstruction and contrastive alignment (e.g., CLIP)
  • Work with graph-structured proximity-network data, collaborating on graph- and topology-aware modeling approaches, and
  • Leverage existing high-performing imaging models for feature extraction and inference, adapting them for co-embedding and building new image models where needed
  • Develop cross-modal alignment strategies relating surface organization to signaling and localization, and use the learned representations to model continuous cell-state structure and the features driving state transitions
  • Present findings internally and externally, and co-author publications
What You'll Bring
  • Essential:
    • PhD in machine learning, computational biology, bioengineering, biophysics, or a related field
    • Experience applying deep learning to images, including use of pretrained vision models
    • Demonstrated experience building both supervised and unsupervised models
    • Experience with multimodal modeling or data fusion across heterogeneous data types
    • Experience with graph neural networks or other graph/network representation learning
    • Proficiency in Python and modern deep learning frameworks (e.g., PyTorch, JAX, or TensorFlow)
  • Nice to Have:
    • Experience with contrastive or self-supervised learning (e.g., CLIP) for multimodal data
    • Familiarity with topology-aware or higher-order modeling (e.g., simplicial or motif-based methods)
    • Background in proteomics or mass spectrometry data analysis
    • Experience with sequencing-based or single-cell omics data analysis
    • Experience with microscopy or spatial imaging analysis in a biological setting
    • Fluency with immunology or single-cell state modeling
    • Experience building reproducible analysis pipelines and contributing to shared or open-source codebases
Compensation
The Chicago, IL base pay for a new hire in this role is $84,150. New hires are typically hired into the lower portion of the range, enabling employee growth in the range over time. Actual placement in range is based on job-related skills and experience, as evaluated throughout the interview process.
This position may be eligible to participate in our discretionary annual performance bonus program. Bonus eligibility and targets are determined in accordance with our total rewards philosophy and may vary by role.
Benefits for the Whole You
We're thankful to have an incredible team behind our work. To honor their commitment, we offer a wide range of benefits to support the people who make all we do possible.
  • Provides a generous employer match on employee 401(k) contributions to support planning for the future.
  • Paid time off to volunteer at an organization of your choice.
  • Funding for select family-forming benefits.
  • Relocation support for employees who need assistance moving

If you're interested in a role but your previous experience doesn't perfectly align with each qualification in the job description, we still encourage you to apply as you may be the perfect fit for this or another role.
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