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Peptide Synthesis Jobs (NOW HIRING)

This role supports customer-driven projects, drives innovation in peptide synthesis and purification, and implements technologies to enhance GMP manufacturing efficiency and cost-effectiveness.

Scientist / Sr Scientist

Torrance, CA · On-site

$94K - $130K/yr

This role supports customer-driven projects, drives innovation in peptide synthesis and purification, and implements technologies to enhance GMP manufacturing efficiency and cost-effectiveness.

Core Technician

Evanston, IL · On-site

$12/hr

The CRN Peptide Synthesis Core is located on the Chicago campus. Please note : The candidate for this position will work in a chemistry laboratory environment. Occasionally a flexible work schedule ...

Peptide Core is seeking a RSE Assistant to join a Core focused on producing synthetic peptides to continuously support many projects in parallel at the IPD, such as biologic therapeutics ...

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Peptide Synthesis information

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$39.5K

$84.8K

$155K

How much do peptide synthesis jobs pay per year?

As of Jul 20, 2026, the average yearly pay for peptide synthesis in the United States is $84,805.00, according to ZipRecruiter salary data. Most workers in this role earn between $67,000.00 and $90,000.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive in the Peptide Synthesis position, and why are they important?

To thrive in Peptide Synthesis, candidates typically need a strong background in organic chemistry or biochemistry, hands-on laboratory experience, and a relevant degree such as a B.S. or M.S. in chemistry or a related field. Proficiency with peptide synthesizers, analytical tools like HPLC and mass spectrometry, and adherence to laboratory safety protocols are commonly required. Attention to detail, problem-solving abilities, and effective communication skills help professionals work efficiently and accurately in a collaborative lab environment. These competencies are crucial for producing high-quality peptides, troubleshooting synthesis issues, and ensuring timely project delivery for research or pharmaceutical development.

What are the typical responsibilities and daily tasks of someone working in Peptide Synthesis?

Professionals in peptide synthesis are responsible for preparing, purifying, and analyzing synthetic peptides using specialized laboratory equipment. On a daily basis, they may set up and operate peptide synthesizers, perform quality control using techniques like HPLC and mass spectrometry, document results, and collaborate with research teams for process optimization. This role often involves troubleshooting synthesis challenges, maintaining laboratory supplies, and adhering to strict safety and quality standards. Working closely with other chemists or biologists, peptide synthesis specialists play a central role in supporting research, drug discovery, and development projects.

What is a Peptide Synthesis job?

A Peptide Synthesis job involves the chemical production of peptides, which are short chains of amino acids used in pharmaceuticals, research, and biotechnology. Professionals in this role operate specialized equipment, follow strict laboratory protocols, and ensure high-purity peptide production. They may also be responsible for troubleshooting synthesis issues, analyzing final products, and maintaining quality control standards. This role requires knowledge of organic chemistry, laboratory techniques, and peptide purification methods.

More about Peptide Synthesis jobs
What cities are hiring for Peptide Synthesis jobs? Cities with the most Peptide Synthesis job openings:
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Scientist / Senior Scientist, Protein Engineering

Scientist / Senior Scientist, Protein Engineering

Kodiak Sciences Inc.

Palo Alto, CA

$105K - $143K/yr

Full-time

Re-posted 8 days ago


Job description

Kodiak Sciences Inc. is a fast-growing, clinical-stage biopharmaceutical company focused on transforming ophthalmology through innovative therapeutics. Our Antibody Biopolymer Conjugate Drug (ABCD) platform integrates protein and peptide engineering & discovery, polymer chemistry, small molecule drug discovery, bioconjugation, and drug delivery technologies to address high-prevalence ophthalmic diseases.
We are seeking a talented Scientist/Senior Scientist to advance peptide therapeutic drug discovery and development programs with a strong emphasis on molecular design, organic synthesis, and analytical characterization.
Key Responsibilities
  • Lead the design, synthesis, and optimization of peptide-based therapeutics, integrating Structure-Activity Relationship (SAR) considerations, developability and conjugation strategies to drive candidate progression.
  • Perform hands-on experimental work including, but not limited to DNA-Encoded Library synthesis, Macrocyclic and Linear Peptide synthesis, polymer conjugation chemistry, purification and analytical evaluation, data interpretation and developability risk assessment.
  • Develop and apply analytical and biophysical methods (e.g., LC-MS, HPLC, NMR, SEC, DLS) to characterize peptides and bioconjugates, including purity, heterogeneity, stability, and aggregation.
  • Collaborate cross-functionally and communicate scientific findings through presentations, reports, and regulatory documentation.
Education / Qualifications
  • Ph.D. in Medicinal Chemistry, Organic Chemistry, Chemical Biology, Biochemistry, or a related field, with either (i) 0–3 years of relevant postdoctoral experience and at least one first-author publication in a high-impact, peer-reviewed journal (preferred), or (ii) 3+ years of relevant industry experience.
  • Experience working with either of the following methodologies, such as Solid Phase Peptide Synthesis (SPPS), DNA-Encoded Library (DEL) synthesis, liquid phase parallel synthesis and/or polymer-based bioconjugates is highly desirable.
  • Strong experience in therapeutic development of peptides, and/or conjugated biologics, experience in analytical characterization is a plus.
  • Proficiency in chromatographic and mass spectrometry-based techniques, with an understanding of developability attributes such as stability, solubility, and manufacturability is a plus.
  • Experience in using software such as PyMol, MOE, Schrödinger, Maestro, DataWarrior, Vortex is a plus.
  • Experience with CD and/or FTIR for peptide secondary structure determination is a plus.
  • Hands-on experience with biochemical assays, including SPR, ELISA, fluorescence-based assays, is a plus.
  • Demonstrated ability to independently drive scientific work in a collaborative, cross-functional environment, with strong problem-solving and communication skills.