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The post-doctoral fellow will have duties that will include basic and translational research projects  in urologic oncology. The Kyprianou lab focuses on the investigation of novel therapeutic targeting in metastatic, castration-resistant prostate cancer and renal cancer towards overcoming advanced disease and in collaboration with Dr. Navneet Dogra's lab are investigating the identification of novel liquid biopsies and biomarkers of therapeutic resistance (exosomes) . The Kyprianou lab is NIH funded and is well established in the field of translational research.  The candidate post-doc will use a wide array of techniques including bioinformatics, immunohistochemical analysis of tumor tissue, pre-clinical PDX models, transgenic mouse models, isolation of extracellular vesicles  from serum, flow-cytometry and molecular biology techniques ( including RT-PCR, confocal microscopy) to define the underlying mechanisms of emergence of metastatic therapeutically resistant tumors and identify extracellular vesicles (EVs) as biomarkers of tumor progression..

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Mount Sinai Health System is one of the largest academic medical systems in the New York metro area, with more than 48,000 employees working across eight hospitals, more than 400 outpatient practices, more than 300 labs, a school of nursing, and a leading school of medicine and graduate education. Mount Sinai advances health for all people, everywhere, by taking on the most complex health care challenges of our time - discovering and applying new scientific learning and knowledge; developing safer, more effective treatments; educating the next generation of medical leaders and innovators; and supporting local communities by delivering high-quality care to all who need it. Through the integration of its hospitals, labs, and schools, Mount Sinai offers comprehensive health care solutions from birth through geriatrics, leveraging innovative approaches such as artificial intelligence and informatics while keeping patients' medical and emotional needs at the center of all treatment. The Health System includes more than 9,000 primary and specialty care physicians; 13 joint-venture outpatient surgery centers throughout the five boroughs of New York City, Westchester, Long Island, and Florida; and more than 30 affiliated community health centers. We are consistently ranked by U.S. News & World Report's Best Hospitals, receiving high "Honor Roll" status, and are highly ranked: No. 1 in Geriatrics, top 5 in Cardiology/Heart Surgery, and top 20 in Diabetes/Endocrinology, Gastroenterology/GI Surgery, Neurology/Neurosurgery, Orthopedics, Pulmonology/Lung Surgery, Rehabilitation, and Urology. New York Eye and Ear Infirmary of Mount Sinai is ranked No. 12 in Ophthalmology. U.S. News & World Report's "Best Children's Hospitals" ranks Mount Sinai Kravis Children's Hospital among the country's best in several pediatric specialties. The Icahn School of Medicine at Mount Sinai is ranked No. 11 nationwide in National Institutes of Health funding and in the 99th percentile in research dollars per investigator according to the Association of American Medical Colleges. Newsweek's "The World's Best Smart Hospitals" ranks The Mount Sinai Hospital as No. 1 in New York and in the top five globally, and Mount Sinai Morningside in the top 20 globally.

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PhD or MD 

SPOC-UAW Local 4100 at Icahn School of Medicine (Post Docs), 869 - Urology - ISM, Icahn School of Medicine

PhD or MD 

Compensation Statement

The Mount Sinai Health System (MSHS) provides salary ranges that comply with the New York City Law on Salary Transparency in Job Advertisements. The salary range for the role is $72,500.00 - $80,000.00 Annually.Actual salaries depend on a variety of factors, including experience, education, and operational need. The salary range or contractual rate listed does not include bonuses/incentive, differential pay or other forms of compensation or benefits.

SPOC-UAW Local 4100 at Icahn School of Medicine (Post Docs), 869 - Urology - ISM, Icahn School of Medicine

As part of their academic training in translational cancer research, the post-doc will be participating in the urology research meetings, journal club, research seminar series at the Tisch Cancer Institute, at mentor guidance. Moreover the post-doc is expected to write & submit research articles for publication in urologic oncology under the mentorship of Dr. Kyprianou. It is anticipated that all or most of the experimental work will be performed at Annenberg, Floor 24.