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Patch Clamp Jobs (NOW HIRING)

Saint Louis University

Post Doctoral Fellow

Saint Louis, MO

$47K - $64K/yr

Prior experience with patch-clamp electrophysiology and advanced microscopy techniques is highly desirable. The Dai lab investigates the fundamental mechanisms of ion channels in excitable membranes ...

Saint Louis University

Post Doctoral Fellow

Saint Louis, MO · On-site

$47K - $64K/yr

Prior experience with patch-clamp electrophysiology and advanced microscopy techniques is highly desirable. The Dai lab investigates the fundamental mechanisms of ion channels in excitable membranes ...

University of Chicago Library

Staff Scientist

Gordon, GA · On-site

$70K - $90K/yr

This role combines electrophysiology (patch clamp) with biochemical and imaging approaches to uncover mechanisms of immune regulation. The scientist will drive protocol development, mentor trainees ...

Astera

In Vitro Neuroscientist

Emeryville, CA · On-site

$60K - $150K/yr

Perform and optimize electrophysiological recordings, including patch clamp and multielectrode array (MEA) platforms * Implement optical and imaging-based methods for monitoring neuronal function ...

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How much do patch clamp jobs pay per week?

As of Jun 27, 2026, the average weekly pay for patch clamp in the United States is $1,444.35, according to ZipRecruiter salary data. Most workers in this role earn between $1,250.00 and $1,625.00 per week, depending on experience, location, and employer.

What are some typical daily responsibilities for someone working in a Patch Clamp role?

A Patch Clamp professional’s daily responsibilities often include preparing biological samples or cultured cells, setting up and calibrating electrophysiology equipment, and performing precise patch clamp recordings to study ion channel activity. Data analysis, troubleshooting technical issues, and maintaining detailed experimental records are also common tasks. Collaboration with other researchers, attending lab meetings, and contributing to manuscript preparation or grant proposals are frequently part of the role. These varied responsibilities help ensure high-quality scientific outcomes and ongoing professional development within the research team.

What is a Patch Clamp job?

A Patch Clamp job typically involves using the patch-clamp technique to study ion channels in biological cells. This role is common in neuroscience, electrophysiology, and pharmaceutical research, where scientists analyze electrical activity in neurons or other cells. Responsibilities may include preparing cell samples, performing recordings, analyzing data, and maintaining laboratory equipment. Professionals in this field often work in academic institutions, biotechnology companies, or pharmaceutical industries to support drug discovery and fundamental research.

What are the key skills and qualifications needed to thrive in the Patch Clamp position, and why are they important?

To thrive as a Patch Clamp technician or researcher, you typically need a strong background in cellular physiology, electrophysiology, and hands-on laboratory skills, often supported by a relevant degree in biology, neuroscience, or a related field. Proficiency with patch clamp amplifiers, data acquisition software (such as pCLAMP), and microscopy is essential, and additional certifications in laboratory safety are beneficial. Attention to detail, problem-solving abilities, and effective teamwork are key soft skills that help individuals excel in this meticulous and collaborative research environment. These competencies are crucial to ensure reliable data collection, accurate interpretation of experimental results, and smooth collaboration within interdisciplinary scientific teams.

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Patch Clamp jobs near you
Post Doctoral Fellow

Post Doctoral Fellow

Saint Louis University

Saint Louis, MO

$47K - $64K/yr

Full-time

Posted 19 days ago

Saint Louis University rating

8.9

Company rating: 8.9 out of 10

Based on 12 frontline employees who took The Breakroom Quiz

28th of 541 rated colleges and universities

Job description

Who is Saint Louis University? Founded in 1818, Saint Louis University is one of the nation's oldest and most prestigious Catholic universities. SLU, which also has a campus in Madrid, Spain, is recognized for world-class academics, life-changing research, compassionate health care, and a strong commitment to faith and service.

A postdoctoral research position is available in the laboratory of Dr. Gucan Dai in the Edward A. Doisy Department of Biochemistry and Molecular Biology at Saint Louis University School of Medicine. We are seeking a highly motivated and skilled scientist with a strong background in biophysics, with a focus on ion channel research. Prior experience with patch-clamp electrophysiology and advanced microscopy techniques is highly desirable.

The Dai lab investigates the fundamental mechanisms of ion channels in excitable membranes using a multidisciplinary approach. Our NIH-funded research integrates structural biology, chemical biology, genetics, fluorescence microscopy, and electrophysiology. The lab is equipped with two cutting-edge patch-clamp electrophysiology/fluorescence imaging systems, including a frequency-domain fluorescence lifetime imaging microscopy system.

Research Focus Areas:

Voltage-sensing mechanisms of voltage-gated ion channels - These channels are key players in conditions such as chronic pain, cardiac arrhythmias, and epileptic seizures. Trainees will gain hands-on experience with advanced techniques like patch-clamp fluorometry (PCF), Forster resonance energy transfer (FRET), and the use of fluorescent noncanonical amino acids (ncAAs).

Lipid-mediated regulation of ion channels and membrane dynamics - This research explores the role of lipids in the regulation of ion channels, with implications for inflammatory and neuropathic pain, Alzheimer's disease, epilepsy, and viral infections. Relevant techniques include whole-cell fluorometry, calcium imaging, TIRF microscopy, and fluorescence lifetime imaging.

We highly encourage individuals interested in this position, please apply for the position from the link or contact us at gucan.dai@health.slu.edu.

Function

Medical Research Primary Appointment 12 mo.

Scheduled Weekly Hours:

40

Saint Louis University is an equal opportunity/affirmative action employer. All qualified candidates will receive consideration for the position applied for without regard to race, color, religion, sex, age, national origin, disability, marital status, sexual orientation, military/veteran status, gender identity, or other non-merit factors. If accommodations are needed for completing the application and/or with the interviewing process, please contact Human Resources at 314-977-5847.

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