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Patch Clamp Jobs (NOW HIRING)

Saint Louis University

Post Doctoral Fellow

Saint Louis, MO · On-site

$47K - $64K/yr

Prior experience with patch-clamp electrophysiology and advanced microscopy techniques is highly desirable. The Dai lab investigates the fundamental mechanisms of ion channels in excitable membranes ...

Saint Louis University

Post Doctoral Fellow

Saint Louis, MO

$47K - $64K/yr

Prior experience with patch-clamp electrophysiology and advanced microscopy techniques is highly desirable. The Dai lab investigates the fundamental mechanisms of ion channels in excitable membranes ...

Allen Institute

Scientist I - Brain Health

Seattle, WA · On-site

Patch-clamp electrophysiology in neuron cell culture or brain slices * Perform data analysis (ImageJ, Excel, R, or Python, etc) and present findings to the team * Maintain detailed lab notebook and ...

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How much do patch clamp jobs pay per week?

As of Jun 6, 2026, the average weekly pay for patch clamp in the United States is $1,444.35, according to ZipRecruiter salary data. Most workers in this role earn between $1,250.00 and $1,625.00 per week, depending on experience, location, and employer.

What are some typical daily responsibilities for someone working in a Patch Clamp role?

A Patch Clamp professional’s daily responsibilities often include preparing biological samples or cultured cells, setting up and calibrating electrophysiology equipment, and performing precise patch clamp recordings to study ion channel activity. Data analysis, troubleshooting technical issues, and maintaining detailed experimental records are also common tasks. Collaboration with other researchers, attending lab meetings, and contributing to manuscript preparation or grant proposals are frequently part of the role. These varied responsibilities help ensure high-quality scientific outcomes and ongoing professional development within the research team.

What is a Patch Clamp job?

A Patch Clamp job typically involves using the patch-clamp technique to study ion channels in biological cells. This role is common in neuroscience, electrophysiology, and pharmaceutical research, where scientists analyze electrical activity in neurons or other cells. Responsibilities may include preparing cell samples, performing recordings, analyzing data, and maintaining laboratory equipment. Professionals in this field often work in academic institutions, biotechnology companies, or pharmaceutical industries to support drug discovery and fundamental research.

What are the key skills and qualifications needed to thrive in the Patch Clamp position, and why are they important?

To thrive as a Patch Clamp technician or researcher, you typically need a strong background in cellular physiology, electrophysiology, and hands-on laboratory skills, often supported by a relevant degree in biology, neuroscience, or a related field. Proficiency with patch clamp amplifiers, data acquisition software (such as pCLAMP), and microscopy is essential, and additional certifications in laboratory safety are beneficial. Attention to detail, problem-solving abilities, and effective teamwork are key soft skills that help individuals excel in this meticulous and collaborative research environment. These competencies are crucial to ensure reliable data collection, accurate interpretation of experimental results, and smooth collaboration within interdisciplinary scientific teams.

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Patch Clamp jobs near you
Senior Scientist I, In Vitro Electrophysiologist

Senior Scientist I, In Vitro Electrophysiologist

AbbVie

North Chicago, IL • On-site

$96K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Posted 23 days ago

AbbVie rating

8.8

Company rating: 8.8 out of 10

Based on 95 frontline employees who took The Breakroom Quiz

11th of 71 rated pharmaceutical

Job description

Company Description
About AbbVie
AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on LinkedIn, Facebook, Instagram, X and YouTube.
Job Description
We are seeking a highly motivated in vitro electrophysiologist to join our collaborative Migraine and Pain drug discovery team. The ideal candidate will bring deep expertise in ion channel biology and patch-clamp electrophysiology to support functional, pharmacological, and mechanistic studies that advance novel therapeutics.
Key Responsibilities Include:
  • Design and execute manual patch-clamp electrophysiology experiments to characterize ion channel pharmacology, biophysical properties, and cellular excitability in relevant cell and disease models including primary, hiPSC-derived, and recombinant cell lines.
  • Lead design, execution, and analysis of studies on automated patch-clamp platforms (e.g. SyncroPatch). This will include both operation and training/guidance of more junior scientists on the instrument.
  • Contribute to studies utilizing multi-electrode (MEA) recordings and complimentary fluorescence-based assays (e.g. calcium imaging, membrane potential assays) as needed.
  • Support target identification, validation, and compound profiling to advance our Neuroscience pipeline, with a focus on pain-relevant ion channel families including both voltage-and ligand-gated channels.
  • Apply broad cell and molecular biology skills to support mechanistic studies and complement electrophysiology-based work (e.g., cell culture, Western blot, Microscopy, transient transfection, RNAi approaches, etc).
  • Read and adapt scientific literature to stay current in the field and advance techniques and innovative approaches
  • Independently generate precise, reliable, and reproducible data in a timely manner; interpret and effectively communicate results to cross-functional project teams and diverse audiences.
  • Contribute to scientific publications and present findings at internal and external scientific meetings and conferences.

Qualifications
Qualifications
  • Bachelor's Degree and 10 years of experience, Master's Degree and 8 years of experience, PhD and no experience necessary in Neuroscience, Biology, or related field.
  • Demonstrated proficiency in manual patch-clamp electrophysiology across multiple recording configurations (e.g. whole-cell, cell-attached, perforated-patch, single-channel) and ion channel pharmacology.
  • Proficiency with electrophysiology data acquisition and analysis software (e.g., Axon, HEKA, or equivalent).
  • Strong quantitative skills in biophysical analysis: concentration-response curves, channel gating kinetics, and state-dependent pharmacology.
  • Experience working with heterologous expression systems (e.g. HEK293 or CHO) and/or primary neurons, DRG neurons, or hiPSC-derived neuronal/sensory neuron preparations.
  • Experience with automated patch-clamp platforms (e.g., SyncroPatch or Qube) is highly valued.
  • Ability to work in a highly collaborative, fast-paced scientific environment towards a common goal of advancing novel therapeutics to impact patients.
  • Additional beneficial qualifications include a background in Neuroscience or pain/migraine and/or experience with ex vivo slice electrophysiology, multi-electrode array (MEA) recordings, or single channel recordings.

Key Competencies:
  • Communicates scientific findings clearly and effectively, both in writing and verbally
  • Independent, flexible thinker with capacity to develop novel methodologies and apply emerging technologies to address key gaps.
  • Strategic thinking that connects experimental approaches with broader program objectives.
  • Applies quantitative and analytical thinking to complex biological problems.
  • Builds strong relationships with peers and actively contributes to a positive, inclusive, and collaborative working environment.

Additional Information
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:
  • The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.
  • We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
  • This job is eligible to participate in our short-term incentive programs.

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company's sole and absolute discretion, consistent with applicable law.
AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.
US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html
US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:
https://www.abbvie.com/join-us/reasonable-accommodations.html

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About AbbVie

Sourced by ZipRecruiter

AbbVie's mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas: immunology, oncology, neuroscience, eye care, virology, women's health, and gastroenterology, in addition to products and services across its Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on Twitter, Facebook, Instagram, YouTube, and LinkedIn.

Industry

Scientific research and development services

Company size

10,000+ Employees

Headquarters location

North Chicago, IL, US

Year founded

2013

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