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Outpatient Infusion Rn Jobs (NOW HIRING)

$55 - $77/hr

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Outpatient Infusion Rn information

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How much do outpatient infusion rn jobs pay per hour?

As of Sep 6, 2026, the average hourly pay for outpatient infusion rn in the United States is $45.96, according to ZipRecruiter salary data. Most workers in this role earn between $36.30 and $50.24 per hour, depending on experience, location, and employer.

What is an outpatient infusion RN?

An Outpatient Infusion RN is a registered nurse who specializes in administering medications and treatments through intravenous (IV) infusion in an outpatient setting, such as a clinic or infusion center. Their responsibilities include starting and monitoring IVs, assessing patient responses, educating patients about their treatments, and collaborating with healthcare providers to ensure safe and effective care. These nurses often work with patients who require therapies like chemotherapy, antibiotics, hydration, or biologic medications but do not need to be hospitalized.

What are the key skills and qualifications needed to thrive as an outpatient infusion RN?

To thrive as an Outpatient Infusion RN, you need strong clinical assessment skills, in-depth knowledge of IV therapy, and an active RN license, often with experience in oncology or infusion therapy. Familiarity with electronic health records (EHRs), infusion pumps, and adherence to safety protocols are essential technical requirements. Excellent communication, patient education, and the ability to remain calm under pressure are crucial soft skills for this role. These competencies ensure safe, efficient, and compassionate care for patients receiving complex infusion treatments in an outpatient setting.

What are some typical challenges an outpatient infusion RN may face, and how can they effectively manage them?

Outpatient Infusion RNs often encounter challenges such as managing multiple patients with varying infusion needs, staying updated on complex medication protocols, and navigating patient anxiety or adverse reactions during treatment. Effective time management, strong communication skills, and thorough knowledge of infusion therapies are crucial for success. Collaborating closely with pharmacists, physicians, and support staff helps ensure safe patient care, while ongoing education and training keep RNs prepared for evolving best practices.

What is the difference between Outpatient Infusion Rn vs Inpatient Infusion Nurse?

AspectOutpatient Infusion RnInpatient Infusion Nurse
Work EnvironmentAmbulatory clinics, outpatient centersHospitals, inpatient units
CertificationsRN license, infusion therapy certification often preferredRN license, infusion therapy certification often required
Patient Care SettingScheduled outpatient visits, home infusionAcute care, hospitalized patients
Work ScheduleTypically outpatient hours, weekdaysVaried shifts, including nights and weekends

Outpatient Infusion Rns primarily work in outpatient clinics providing scheduled infusion treatments, while Inpatient Infusion Nurses care for hospitalized patients requiring infusion therapy. Both roles require RN licensure and infusion certifications, but their work environments and schedules differ significantly.

How much do outpatient infusion RNs make?

Outpatient infusion RNs typically earn a median annual salary of around $75,000 to $85,000, depending on experience, location, and certifications. Salaries can vary based on the healthcare setting, workload, and additional skills such as IV therapy or patient education.
More about Outpatient Infusion Rn jobs

What cities are hiring for Outpatient Infusion Rn jobs?

Cities with the most Outpatient Infusion Rn job openings:

What states have the most Outpatient Infusion Rn jobs?

States with the most job openings for Outpatient Infusion Rn jobs include:

Infographic showing various Outpatient Infusion Rn job openings in the United States as of August 2026, with employment types broken down into 3% As Needed, 51% Full Time, 13% Part Time, and 33% Contract. Highlights an 99% Physical, and 1% Remote job distribution, with an average salary of $95,606 per year, or $46 per hour.

Chemotherapy/Infusion Registered Nurse

Aptive

Charleston, SC • On-site

$62.51/hr

Other

Re-posted 10 hours ago


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Job description

Job Summary Job Title:

Chemotherapy / Infusion Registered Nurse (RN)

Compensation: $55.00/hr plus benefits

Location

Charleston, SC VAMC - Chemotherapy & Infusion Suite(VA Medical Center / Outpatient Infusion Clinic)

Work Schedule
  • Clinic Coverage: Weekdays, weekends, and federal holidays as required

  • Shift Options:

    • Day Shift: 7:30 a.m. – 4:00 p.m.

    • Day Shift: 8:00 a.m. – 4:30 p.m.

    • Day Shift: 8:30 a.m. – 5:00 p.m.

Position Overview

The Chemotherapy / Infusion Registered Nurse (RN) is a highly skilled professional nurse who provides specialized nursing care to patients receiving chemotherapy, immunotherapy, and infusion-related treatments within the Chemotherapy & Infusion Suite. Under the supervision of the Nurse Manager, the Contract Chemotherapy/Infusion RN maintains accountability for coordinating and delivering safe, effective, and patient-centered care.

The RN provides care to individuals, families, and groups in accordance with the standards and ethical principles established by the American Nurses Association (ANA) and the Oncology Nursing Society (ONS). Contractor nurses are assigned based on patient care needs and individual experience.

Primary Responsibilities Duties and Responsibilities Assessment & Clinical Care
  • Identify and assess physiological, psychological, social, and environmental factors affecting patients undergoing chemotherapy and infusion therapy.

  • Demonstrate knowledge and skills appropriate to the care of adult and geriatric patients across all stages of treatment.

  • Assess, monitor, and treat patient responses to antineoplastic agents, immunotherapy, and infusion therapies.

  • Recognize and respond effectively to medical emergencies, infusion or transfusion reactions, and proactively intervene to prevent complications.

Medication & Treatment Administration
  • Administer, monitor, document, and evaluate chemotherapy, biotherapy, immunotherapy, blood products, iron infusions, antibiotics, IV fluids, and other prescribed treatments in accordance with ONS guidelines and medical center policies.

  • Perform venipuncture and manage vascular access devices including Port-A-Cath, PASport implanted devices, and PICC lines.

  • Safely manage chemotherapy spills and adhere to hazardous drug handling protocols.

  • Perform 12-lead electrocardiographic monitoring and interpret relevant laboratory values.

Advanced Nursing Skills
  • Provide Basic Life Support (BLS), airway management, and appropriate use of AED when indicated.

  • Perform tracheostomy care, gastrostomy/PEG tube care, urinary catheterization (indwelling and intermittent), blood glucose testing, and other diagnostic or therapeutic procedures as required.

  • Administer high-alert medications and oral or IV antineoplastic and immunotherapy agents as prescribed.

Documentation & Communication
  • Review electronic and/or paper medical records for provider orders and treatment protocols.

  • Document patient assessments, interventions, and outcomes using approved VA forms and computerized systems.

  • Promptly notify providers of significant changes in patient condition or other pertinent clinical information.

Patient Education & Care Coordination
  • Develop and implement individualized patient education and teaching plans based on assessed needs.

  • Address patient concerns, answer questions, and provide education regarding treatment plans, side effects, and self-care strategies.

  • Coordinate care and refer patients to other disciplines as appropriate, including nutrition, social work, and specialty services.

  • Collaborate with interdisciplinary team members to influence positive patient outcomes across the continuum of care.

Team & Operational Responsibilities
  • Work collaboratively with the Chemotherapy & Infusion team and participate in interdisciplinary meetings.

  • Maintain responsibility for providing clinical coverage to the Chemotherapy & Infusion Center.

  • Practice in adherence to professional nursing standards, ethical principles, and facility policies.

Special Assignments
  • May be required to care for COVID-19 positive patients and Patients Under Investigation (PUI) in the Chemotherapy/Infusion Clinic setting.

Minimum Qualifications Qualifications Required
  • Active, unrestricted Registered Nurse (RN) license in a U.S. state, territory, or the District of Columbia.

  • Must have Associates in Nursing; BSN in Nursing is preferred
  • Must be ONC RN Certified
  • Demonstrated experience in chemotherapy, infusion, oncology, or hematology nursing.

  • Ability to work independently and manage complex patient care in a fast-paced clinical environment.

  • Strong assessment, critical thinking, and emergency response skills.

EEO Statement

Aptive is an equal opportunity employer. We consider all qualified applicants for employment without regard to race, color, national origin, religion, creed, sex, sexual orientation, gender identity, marital status, parental status, veteran status, age, disability, or any other protected class.

Veterans, members of the Reserve and National Guard, and transitioning active-duty service members are highly encouraged to apply.

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