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Office Rn Jobs in Greenville, SC (NOW HIRING)

BAYADA Home Health Care

Pediatric Nurse - RN

Taylors, SC · On-site

$30 - $32/hr

Discover a Better Nursing Experience Our Upstate Skilled Office is interested in a Registered Nurse (RN) who has a passion for homecare to join our Skilled Private Duty Nursing team. We believe our ...

BAYADA Home Health Care

Pediatric Nurse - RN

Taylors, SC · On-site

$30 - $32/hr

Discover a Better Nursing Experience Our Upstate Skilled Office is interested in a Registered Nurse (RN) who has a passion for homecare to join our Skilled Private Duty Nursing team. We believe our ...

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All JobsOffice Rn JobsOffice Rn Jobs in Greenville, SC

Office Rn information

See Greenville, SC salary details

$22

$29

$38

How much do office rn jobs pay per hour?

As of Sep 6, 2026, the average hourly pay for office rn in Greenville, SC is $29.16, according to ZipRecruiter salary data. Most workers in this role earn between $25.48 and $31.63 per hour, depending on experience, location, and employer.

What is an Office RN?

Office RNs, or Office Registered Nurses, are licensed nurses who work in outpatient settings such as doctors' offices, clinics, or medical group practices. Their primary responsibilities include patient assessment, administering medications and injections, assisting with minor procedures, and providing patient education. Unlike hospital nurses, Office RNs typically work regular business hours and handle a wide range of administrative and clinical tasks. They play a vital role in ensuring smooth patient flow and supporting physicians in delivering quality care.

What does an Office RN do?

Office RNs work in a medical office or clinic setting, treating patients and assisting physicians. As an office registered nurse, you perform patient assessments, record vitals, and update patient records. You work with a doctor to provide education on procedures, answering questions and arranging for follow-ups visits. As an RN in a medical office, you tend to have the most face-to-face time with a patient. Your responsibilities include data entry, providing basic care, and helping patients understand and follow the doctor’s orders.

What are the key skills and qualifications needed to thrive as an Office RN?

To thrive as an Office RN, you need a current RN license, clinical assessment skills, and experience in outpatient or ambulatory care settings. Familiarity with electronic health record (EHR) systems, scheduling software, and basic office equipment is typically required. Exceptional communication, organizational skills, and the ability to multitask make someone stand out in this role. These skills are crucial for efficiently managing patient care, maintaining accurate records, and ensuring smooth office operations.

What are some common challenges Office RNs face when balancing administrative duties with patient care responsibilities?

Office RNs often juggle a variety of tasks, from direct patient care and patient education to administrative responsibilities like coordinating appointments and maintaining medical records. One common challenge is managing time efficiently to ensure that both clinical and clerical duties are completed without compromising patient care quality. Additionally, adapting to evolving healthcare technologies and electronic health record systems can require ongoing learning. Successful Office RNs typically develop strong organizational skills and collaborate closely with physicians, medical assistants, and front office staff to maintain a smooth workflow.

What is the difference between Office Rn vs Medical Assistant?

AspectOffice RnMedical Assistant
CredentialsRegistered Nurse license, possibly additional certificationsHigh school diploma or GED, certification preferred
Work EnvironmentClinics, hospitals, healthcare officesDoctor's offices, clinics, outpatient facilities
Job ResponsibilitiesPatient assessments, care planning, administering medicationsVital signs, patient prep, administrative tasks

Office Rns and Medical Assistants both work in healthcare settings, but Office Rns have nursing credentials and handle more complex patient care tasks, while Medical Assistants focus on administrative duties and basic patient support. Understanding these differences helps in choosing the right career path or job search focus.

More about Office Rn jobs

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What job categories do people searching Office Rn jobs in Greenville, SC look for?

The top searched job categories for Office Rn jobs in Greenville, SC are:

What cities near Greenville, SC are hiring for Office Rn jobs?

Cities near Greenville, SC with the most Office Rn job openings:

Office Rn jobs near you
Infographic showing various Office Rn job openings in Greenville, SC as of August 2026, with employment types broken down into 1% As Needed, 85% Full Time, 12% Part Time, and 2% Contract. Highlights an 91% Physical, 3% Hybrid, and 6% Remote job distribution, with an average salary of $60,663 per year, or $29.2 per hour.

Registered Nurse (RN) - Specialty Care Ambulatory, Greenville OB/GYN, FT

Prisma Health

Greenville, SC

Full-time

Medical

Re-posted 24 days ago

Prisma Health rating

7.1

Company rating: 7.1 out of 10

Based on 351 frontline employees who took The Breakroom Quiz

379th of 898 rated healthcare providers

Job description

Inspire health. Serve with compassion. Be the difference.

Job Summary

Provides and coordinates advanced nursing care in a non-acute specialty ambulatory, medical office, clinic or urgent care setting in accordance with the State Board of Nursing, Nurse Practice Act, professional standards of care, state regulations, accreditation standards and Prisma Health's philosophy, policies and procedures.

Bonus

This position is bonus eligible, follow this link for details.

Essential Functions

  • All team members are expected to be knowledgeable and compliant with Prisma Health's purpose:Inspire health.Serve with compassion.Be the difference

  • Provides direct nursing care within established policies, procedures, and protocols and in accordance with regulatory scope of practice and Board of Nursing in the state in which work is performed.

  • Provides advanced patient care based upon individualized plan of care including patient's physical, emotional, cultural, spiritual, psychosocial, and educational needs.

  • Maintains an advanced knowledge base of disease entities, medications, and treatments specific to the medicine specialty practice that performs specialized procedures using advanced tools and monitoring.

  • Performs or assists with procedures specific to the specialty (e.g., chemotherapy, IUI, nitrous oxide administration, insulin therapy, etc.).

  • Conduct in-depth assessments and monitoring specific to the specialty, which may involve specialized diagnostic tests and managing complex treatments.

  • Focuses on targeted, complex, advanced care and performs specialized procedures or treatments and administers prescribed medications.

  • Utilizes the unique knowledge, skills, and competencies required in ambulatory care nursing practice to promote wellness, restore health, and address health-related situational problems.

  • Assesses patients' needs and applies advanced ambulatory care nursing knowledge and evidence-based nursing practice when developing an individualized plan of care for each patient.

  • Coordinates, and documents patient care in a knowledgeable, skillful, and consistent manner. This includes patient assessment, education, medication administration, treatments, and patient safety.

  • Delegates tasks and duties to healthcare team members in accordance with the patient's needs and the team member's capabilities and qualifications.

  • Adhere to infection control and safety protocols.

  • Communicates appropriate information regarding patient condition or concerns to other health care team members.

  • Educates patients and families to appropriately perform any recommended post-visit self-care tasks.

  • Integrates patient and family education throughout the delivery of care so they may make informed health related decisions.

  • Provides a compassionate and therapeutic environment for patients and their families.

  • Serves as a role model and participates in educating and mentoring other members of the care team.

  • Attends department and organization meetings.

  • Completes annual and as needed compliance training.

  • Practices safe, efficient use of supplies and resources.

  • Maintains a clean, safe, and caring environment for patients, family and other staff.

  • Assumes responsibility for one's own professional development and continuing education.

  • May serve as a preceptor, unit champion, or participate in shared governance.

  • Adheres to all compliance, policies and procedures of the organization.

  • Performs other duties as assigned.

Supervisory/Management Responsibility

  • This is a non-management job that will report to a supervisor, manager, director, or executive.

Minimum Requirements

  • Education - Associate degree in Nursing (AD N). BSN preferred.

  • Experience - One (1) year of clinical nursing experience within specialty or related applicable specialty.

In Lieu Of

  • In lieu of an associate's degree in nursing, will accept an RN diploma or certificate with a current RN compact/multistate license recognized by the NCSBN Compact State or a license to practice as an RN in the state the team member is working.

  • In lieu of one (1) year of registered nurse experience, may accept one (1) year of licensed practical nurse (LPN) experience.

Required Certifications, Registrations, Licenses

  • Holds a current RN compact/multistate license recognized by the NCSBN Compact State or is licensed to practice as an RN in the state the team member is working.

  • Certification in specialty area preferred.

Knowledge, Skills and Abilities

  • IV insertion and maintenance skills preferred

Work Shift

Day (United States of America)

Location

Greenville OB/GYN

Facility

2063 Greenville Ob/Gyn - Main

Department

20631000 Greenville Ob/Gyn - Main-Practice Operations

Share your talent with us! Our vision is simple: to transform healthcare for the benefits of the communities we serve. The transformation of healthcare requires talented individuals in every role here at Prisma Health.

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