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Nurse Practitioner Position Jobs in Rochester, MN

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Nurse Practitioner Position information

See Rochester, MN salary details

$42.2K

$132.4K

$203.3K

How much do nurse practitioner position jobs pay per year?

As of Jun 13, 2026, the average yearly pay for nurse practitioner position in Rochester, MN is $132,444.00, according to ZipRecruiter salary data. Most workers in this role earn between $109,800.00 and $152,500.00 per year, depending on experience, location, and employer.

How to make 200,000 as an NP?

To earn $200,000 as a nurse practitioner, professionals often work in high-demand specialties such as acute care or anesthesia, gain extensive experience, and may take on additional shifts or leadership roles. Advanced certifications, a strong clinical skill set, and working in urban or high-cost-of-living areas can also contribute to higher earning potential.

Can you make 300K as an NP?

Nurse practitioners can potentially earn $300,000 or more annually, especially with extensive experience, specialization, working in high-demand areas, or taking on leadership roles. However, such salaries are typically above the national average and may require additional certifications, overtime, or working in private practices or specialized fields.

What are some common challenges Nurse Practitioners face when transitioning into a new healthcare setting?

Nurse Practitioners often encounter challenges such as adapting to new electronic health record systems, understanding unique patient populations, and building collaborative relationships with multidisciplinary teams. Adjusting to the protocols and workflow of a new clinic or hospital can require flexibility and proactive communication. However, most healthcare organizations offer orientation and mentorship programs to support Nurse Practitioners during this transition, helping them integrate smoothly and deliver quality patient care.

What is a Nurse Practitioner?

A Nurse Practitioner (NP) is an advanced practice registered nurse who is trained to assess patient needs, order and interpret diagnostic tests, diagnose illnesses, and prescribe medications. NPs can provide a range of healthcare services that are similar to those offered by physicians, and often focus on health promotion, disease prevention, and health education. They can work independently or alongside doctors in various settings such as hospitals, clinics, and private practices. Nurse Practitioners often specialize in areas like family practice, pediatrics, or geriatrics, and play a critical role in expanding access to healthcare.

What is the difference between Nurse Practitioner Position vs Physician Assistant?

AspectNurse Practitioner PositionPhysician Assistant
Required CredentialsMaster's or Doctorate in Nursing, national certificationMaster's degree, national certification (PANCE)
Work EnvironmentClinics, hospitals, primary and specialty careHospitals, clinics, surgical teams, primary care
Scope of PracticeDiagnose, treat, prescribe, often focus on holistic careDiagnose, treat, prescribe, often work under physician supervision

The Nurse Practitioner Position and Physician Assistant roles share many similarities, including work environments and certification requirements. However, Nurse Practitioners often have a focus on holistic patient care and may have more autonomy depending on state laws. Both roles are vital in healthcare teams, but their scope and training slightly differ.

What NP position pays the most?

The highest-paying nurse practitioner positions are often in specialized fields such as anesthesiology, psychiatric-mental health, and neonatal care, with anesthetist nurse practitioners typically earning the most due to the advanced skills and certifications required. These roles often involve working in hospitals or surgical settings and may require additional certifications like the Certified Registered Nurse Anesthetist (CRNA). Salary can vary based on experience, location, and employer, but specialized NP roles generally offer higher compensation than primary care positions.

What are the key skills and qualifications needed to thrive as a Nurse Practitioner, and why are they important?

To thrive as a Nurse Practitioner, you need advanced clinical knowledge, patient assessment skills, and a master's or doctoral degree in nursing along with national certification and state licensure. Familiarity with electronic health records (EHRs), diagnostic equipment, and prescribing systems is commonly required. Exceptional interpersonal communication, critical thinking, and leadership abilities distinguish top performers in this role. These competencies are crucial for delivering high-quality, autonomous patient care and ensuring positive health outcomes.

What else can I do with my nurse practitioner degree?

A nurse practitioner degree allows for roles in primary care, specialty practice, healthcare administration, research, and education. Many NPs also pursue certifications in areas like family practice, pediatrics, or mental health to expand their scope and career options.
What cities near Rochester, MN are hiring for Nurse Practitioner Position jobs? Cities near Rochester, MN with the most Nurse Practitioner Position job openings:
Infographic showing various Nurse Practitioner Position job openings in Rochester, MN as of June 2026, with employment types broken down into 63% Full Time, 29% Part Time, 4% Temporary, and 4% Contract. Highlights an 92% In-person, and 8% Remote job distribution, with an average salary of $132,444 per year, or $63.7 per hour.
Nurse Practitioner or Physician Assistant - Rapid Diagnostics Team

Nurse Practitioner or Physician Assistant - Rapid Diagnostics Team

Mayo Clinic

Rochester, MN • On-site

$110K - $143K/yr

Full-time

Posted 2 days ago


Mayo Clinic rating

7.8

Company rating: 7.8 out of 10

Based on 678 frontline employees who took The Breakroom Quiz

130th of 872 rated healthcare providers


Job description

Job Description
Caring for 75,000 patients per year, the Saint Marys Hospital Emergency Department at Mayo Clinic is a regional level 1 trauma center and is also the base of operations for nationally regarded Air and Ground Transportation programs. We are expanding our practice to staff a dedicated Emergency Department Observation Unit (EDOU), operated by Department of Emergency Medicine providers and embedded in the ED practice. The EDOU provides 24/7/365 coverage and delivers focused, time-limited evaluation and treatment for patients who require care beyond the initial ED visit but are expected to be discharged within 24 hours.
In the EDOU clinical setting the NP/PA serves as an independent provider, collaborates with physicians, and works with a variety of other healthcare professionals. The NP/PA will provide comprehensive assessment, diagnosis, ordering, conducting and interpreting diagnostic tests, prescription of pharmacological agents, and patient education. Common EDOU presentations include chest pain, syncope, TIA, abdominal pain, asthma and COPD exacerbations, cellulitis, dehydration, pyelonephritis, and atrial fibrillation. The NP/PA will also perform a variety of procedures including laceration repair, I&D, lumbar puncture, paracentesis, and ultrasound-guided access. Reassessment, escalation of care when needed, and timely disposition are central to the role.
Our practice is unique in that we have the benefits of a teaching institution with a multitude of practice supporting education as well as a variety of research opportunities. We see patients that are unique to an academic center as well as those common to community hospitals. Mayo Clinic values the skills and expertise of the NP/PA in Emergency Medicine and observation care. We look forward to adding a physician assistant or nurse practitioner to our EDOU team practice. Join a positive, patient-focused environment where you and the physicians become partners and mutual advisors. With supervision and management by both physicians and other NPs and PAs, you're supported by people who understand your professional needs and goals.
Inquiries may contact: Maddie Ecklund, Provider Recruiter - ecklund.madeline@mayo.edu
Qualifications
Nurse Practitioner: Master's-prepared graduate of an accredited school of nursing and Nurse Practitioner program. Current Minnesota RN and APRN license and certification as a Family Nurse Practitioner (FNP) or Emergency Nurse Practitioner (ENP).
Physician Assistant: Graduate of accredited Physician Assistant program with current PA certification by NCCPA and registration as a PA by the Minnesota State Board of Medical Practice.
Registration with the U.S. Drug Enforcement Agency (DEA) is required. BLS, ACLS, PALS, and ATLS are required.
Two years as an experienced NP or PA in Emergency Medicine, observation medicine, or hospital medicine preferred. ED or hospital experience preferred. New graduates who have completed an applicable fellowship may be considered.
Candidates should apply with a resume and/or CV, cover letter, and two letters of recommendation.

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About Mayo Clinic

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Mayo Clinic is the largest integrated, not-for-profit medical group practice in the world. We're building the future, one where the best possible care is available to everyone — and more people can heal at home. Our relentless research turns into earlier diagnoses and new cures. That's how we inspire hope in those who need it most. At Mayo Clinic, experts work together to solve the most challenging unmet needs of patients. Our history of innovation dates back almost 150 years, when brothers Will and Charlie Mayo pioneered an integrated, team-based approach to medicine. Today, that trailblazing spirit drives innovations like Mayo Clinic Platform — which powers new technologies to change how care is delivered to all.

Industry

Hospitals

Company size

10,000+ Employees

Headquarters location

Rochester, MN, US

Year founded

1919