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Next Generation Sequencing Jobs in California (NOW HIRING)

As a Research Scientist I/II, you will provide experience in next-generation-sequencing (NGS)-based analyses of DNA. As a Research Scientist in Genomics, you will contribute to the program ...

Conduct independent experimentation, including reagent preparation and Quality Control (QC) for Next Generation Sequencing (NGS) assays * Maintain detailed laboratory notebooks, document results ...

Join Natera's Bio Development Team as a Design Transfer Scientist to lead the transition of our market-leading In Vitro Diagnostic (IVD) Next-Generation Sequencing (NGS) assays from R&D into scalable ...

... Next-Generation Sequencing (NGS) workflows. Every sample represents a real person, and you will work in a fast-paced, highly regulated environment that balances a deep mission for patient care with ...

Showing results 41-60

Next Generation Sequencing information

See California salary details

$28.1K

$65.4K

$114.5K

How much do next generation sequencing jobs pay per year?

As of Aug 21, 2026, the average yearly pay for next generation sequencing in California is $65,401.00, according to ZipRecruiter salary data. Most workers in this role earn between $38,500.00 and $81,900.00 per year, depending on experience, location, and employer.

What is next generation sequencing?

A Next Generation Sequencing (NGS) job involves working with advanced DNA and RNA sequencing technologies to analyze genetic material. Professionals in this field may design experiments, prepare biological samples, operate sequencing instruments, and interpret genomic data. Roles can vary from research scientists and bioinformaticians to lab technicians and data analysts. NGS is widely used in medicine, agriculture, and biotechnology for applications such as disease research, personalized medicine, and evolutionary studies. Strong skills in molecular biology, computational analysis, and data interpretation are typically required.

What does someone working in next generation sequencing do?

Professionals in Next Generation Sequencing typically spend their days preparing and processing biological samples, operating sequencing instruments, and analyzing genomic data. They are responsible for troubleshooting technical issues, maintaining laboratory equipment, and ensuring quality control throughout the sequencing workflow. Collaboration with cross-functional teams—such as bioinformaticians, clinicians, and research scientists—is common to interpret sequencing results and contribute to project goals. This role also involves detailed record-keeping and adherence to regulatory or laboratory standards, making organization and communication important aspects of the job.

What are the key skills and qualifications needed to thrive in next generation sequencing?

To excel in a Next Generation Sequencing (NGS) role, you need a strong background in molecular biology, genomics, and data analysis, often supported by a degree in a life science field. Proficiency with NGS platforms (such as Illumina or Oxford Nanopore), laboratory automation tools, and bioinformatics software is highly valued, alongside relevant certifications in genomics or molecular diagnostics. Strong problem-solving abilities, attention to detail, and effective teamwork and communication skills set successful professionals apart. These competencies ensure high-quality sequencing results, efficient workflow, and productive collaboration in fast-paced research or clinical environments.

What are the most commonly searched types of Next Generation Sequencing jobs in California?

The most popular types of Next Generation Sequencing jobs in California are:

What job categories do people searching Next Generation Sequencing jobs in California look for?

The top searched job categories for Next Generation Sequencing jobs in California are:

What cities in California are hiring for Next Generation Sequencing jobs?

Cities in California with the most Next Generation Sequencing job openings:

Infographic showing various Next Generation Sequencing job openings in California as of August 2026, with employment types broken down into 84% Full Time, 10% Part Time, and 6% Contract. Highlights an 92% Physical, 3% Hybrid, and 5% Remote job distribution, with an average salary of $65,401 per year, or $31.4 per hour.

Research Scientist I/II

Freenome

Brisbane, CA

$132K - $167K/yr

Full-time

Posted 28 days ago


Job description

About this opportunity:

At Freenome, you will help develop the assay technologies used to analyze patient samples and contribute to our mission of early detection and intervention in human disease. As a Research Scientist I/II, you will provide experience in next-generation-sequencing (NGS)-based analyses of DNA. As a Research Scientist in Genomics, you will contribute to the program's technical base by creating and optimizing new next-generation sequencing (NGS) assays and workflows for DNA/RNA, or to the program's scientific base by elevating our understanding of the biological context of these assay signals in cancer. In this role, you will perform studies to evaluate emergent technologies that have the potential to improve our diagnostic tests, and collect and analyze NGS datasets (including genomics, epigenomics, and transcriptomics) for biomarker discovery. You will also work closely with computational biologists and machine learning scientists to provide biological and technical insights, and to provide new data sources to enhance ongoing computational research projects.

The role reports to a Manager of Molecular Research. This role will be an Onsite role.

What you'll do:

  • Independently design and execute experiments to help optimize the performance of Freenome's new or existing assays.
  • Prototype new next-generation sequencing (NGS) methods, optimize the performance of existing assays, and execute biomarker discovery studies on clinical samples.
  • Assist with project planning and timeline generation and work with cross-functional teams to coordinate tasks within and across projects.
  • Take detailed notes, gather high-quality data, and openly communicate on lessons learned while performing experiments.
  • Independently troubleshoot workflows and understand the rationale behind workflow optimization choices.
  • Help with process improvements across the lab by thinking critically about the execution of all experiments.
  • Perform advanced analysis and data visualization of results to answer experimental questions and guide next steps.
  • Prepare and present experiment or project results at internal meetings, with clear articulation of goals, results, conclusions, and how results presented fit in to broader project.

Must haves:

  • PhD in molecular biology, biochemistry, genetics, or a related field or Bachelor's or Master's with 8+ years experience post-Bachelor's in the life sciences (industry and/or academia).
  • Hands-on experience with and expert-level knowledge in NGS based workflows including sample preparation, library preparation, target capture, and sequencing.
  • Biological understanding of human cell-free nucleic acids, single-cell analysis methods, immunology, and/or cancer biology.
  • Ability to perform advanced data analysis and critically examine experimental results.
  • Proven track record of designing and running successful experiments, preparing data for review, and giving effective scientific presentations.
  • Clear and proactive communication skills and ability to collaborate effectively with team members in the same and adjacent disciplines.
  • Flexible and highly motivated to learn new skills and comfortable adapting to changing priorities.

Nice to haves:

  • Ability to perform bioinformatic analysis in a scientific programming language (e.g., Python or R).
  • Experience handling and preparing blood and/or tissue samples.
  • Experience running high-throughput experimental designs and/or assays on an automated liquid handling platform.
  • Experience using ELN (electronic lab notebook) and LIMS (lab information management system).

Benefits and additional information:

The US target range of our base salary rate for new hires is $132,050 - $167,475. You will also be eligible to receive equity, cash bonuses, and a full range of medical, financial, and other benefits depending on the position offered.  Please note that individual total compensation for this position will be determined at the Company's sole discretion and may vary based on several factors, including but not limited to, location, skill level, years and depth of relevant experience, and education. We invite you to check out our career page @ freenome.com/job-openings/ for additional company information.  

Freenome is proud to be an equal-opportunity employer, and we value diversity. Freenome does not discriminate on the basis of race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical condition, pregnancy, genetic information, gender, sexual orientation, gender identity or expression, veteran status, or any other status protected under federal, state, or local law.

Applicants have rights under Federal Employment Laws.  

  • Family & Medical Leave Act (FMLA)
  • Equal Employment Opportunity (EEO)
  • Employee Polygraph Protection Act (EPPA)

California applicants please review the CCPA Notice at Collection here:

  • California Consumer Privacy Act (CCPA)

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