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Next Generation Sequencing Jobs in California (NOW HIRING)

Freenome

Research Scientist I/II

Brisbane, CA · On-site

$132K - $167K/yr

As a Research Scientist I/II, you will provide experience in next-generation-sequencing (NGS)-based analyses of DNA. As a Research Scientist in Genomics, you will contribute to the program ...

Freenome

Research Scientist I/II

Brisbane, CA

$132K - $167K/yr

As a Research Scientist I/II, you will provide experience in next-generation-sequencing (NGS)-based analyses of DNA. As a Research Scientist in Genomics, you will contribute to the program ...

Natera

Associate Scientist, R&D

San Carlos, CA · Hybrid

Conduct independent experimentation, including reagent preparation and Quality Control (QC) for Next Generation Sequencing (NGS) assays * Maintain detailed laboratory notebooks, document results ...

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Next Generation Sequencing information

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$28.1K

$65.4K

$114.5K

How much do next generation sequencing jobs pay per year?

As of Aug 19, 2026, the average yearly pay for next generation sequencing in California is $65,401.00, according to ZipRecruiter salary data. Most workers in this role earn between $38,500.00 and $81,900.00 per year, depending on experience, location, and employer.

What is next generation sequencing?

A Next Generation Sequencing (NGS) job involves working with advanced DNA and RNA sequencing technologies to analyze genetic material. Professionals in this field may design experiments, prepare biological samples, operate sequencing instruments, and interpret genomic data. Roles can vary from research scientists and bioinformaticians to lab technicians and data analysts. NGS is widely used in medicine, agriculture, and biotechnology for applications such as disease research, personalized medicine, and evolutionary studies. Strong skills in molecular biology, computational analysis, and data interpretation are typically required.

What does someone working in next generation sequencing do?

Professionals in Next Generation Sequencing typically spend their days preparing and processing biological samples, operating sequencing instruments, and analyzing genomic data. They are responsible for troubleshooting technical issues, maintaining laboratory equipment, and ensuring quality control throughout the sequencing workflow. Collaboration with cross-functional teams—such as bioinformaticians, clinicians, and research scientists—is common to interpret sequencing results and contribute to project goals. This role also involves detailed record-keeping and adherence to regulatory or laboratory standards, making organization and communication important aspects of the job.

What are the key skills and qualifications needed to thrive in next generation sequencing?

To excel in a Next Generation Sequencing (NGS) role, you need a strong background in molecular biology, genomics, and data analysis, often supported by a degree in a life science field. Proficiency with NGS platforms (such as Illumina or Oxford Nanopore), laboratory automation tools, and bioinformatics software is highly valued, alongside relevant certifications in genomics or molecular diagnostics. Strong problem-solving abilities, attention to detail, and effective teamwork and communication skills set successful professionals apart. These competencies ensure high-quality sequencing results, efficient workflow, and productive collaboration in fast-paced research or clinical environments.

What are the most commonly searched types of Next Generation Sequencing jobs in California?

The most popular types of Next Generation Sequencing jobs in California are:

What are popular job titles related to Next Generation Sequencing jobs in California?

For Next Generation Sequencing jobs in California, the most frequently searched job titles are:

What job categories do people searching Next Generation Sequencing jobs in California look for?

The top searched job categories for Next Generation Sequencing jobs in California are:

What cities in California are hiring for Next Generation Sequencing jobs?

Cities in California with the most Next Generation Sequencing job openings:

Next Generation Sequencing jobs near you
Infographic showing various Next Generation Sequencing job openings in California as of August 2026, with employment types broken down into 84% Full Time, 10% Part Time, and 6% Contract. Highlights an 92% Physical, 3% Hybrid, and 5% Remote job distribution, with an average salary of $65,401 per year, or $31.4 per hour.

Senior Marine Invertebrate Research Associate - 140290

UC San Diego

San Diego, CA • On-site

$36.13 - $58.11/hr

Other

This job post has expired today. Applications are no longer accepted.

Job description

UCSD Layoff from Career Appointment: Apply by 08/07/2026 for consideration with preference for rehire. All layoff applicants should contact their Employment Advisor.

Reassignment Applicants: Eligible Reassignment clients should contact their Disability Counselor for assistance.

DESCRIPTION

Under general supervision, assist in field sampling of marine invertebrates, sorting identifying, photography, subsampling and vouchering for Museums. Perform DNA extraction from a wide range of preserved and frozen marine invertebrate tissues. Amplify 'barcode' regions of DNA using PCR for these invertebrates as well as algae extractions provided from other laboratories. Prepare products for DNA barcoding using Sanger or alternative methods of sequencing (MinIon, Illumina) and troubleshoot technical issues to ensure high-quality results. Evaluate DNA sequence data, assess sequence identity, and assemble sequences using Geneious software. Submit barcode sequences to BOLD (with specimen images) and GenBankPerform. Perform species delimitation analyses to guide choice of genome skimming targets. For next-generation sequencing (NGS) genome skimming, assess DNA quantity and amplify extractions (Genomiphi) if needed. Analyze genome skimming data for assembling mitochondrial genomes with annotation and nuclear loci such as 18S rRNA. Submit to GenBank and deal with troubleshooting issues to ensure verified status of mitogenomes. Contribute to data interpretation for phylogenetic and population genetic analyses, distribution maps, organize sequences, and maintain comprehensive tracking systems and databases. Provide regular updates and summaries of results for monthly reporting meetings. Coordinate with Museum collections on taxonomy and names of sequences and update databases as needed. Provide guidance and training to other research associates.

QUALIFICATIONS

  • Bachelor's degree in natural sciences such as Biology, Marine Biology, Oceanography or a comparable discipline, or an equivalent combination of education and experience. Master's degree preferred.

  • Knowledge of marine invertebrate diversity and taxonomy. Ability to collect, sort photograph and process intertidal specimens for DNA and vouchering to Museums.

  • Theoretical knowledge and practice in phylogenetic analysis of sequence data.

  • Proficiency in DNA extraction from a variety of tissue types and assessment of sample quality.

  • Experience in DNA quantification and analysis for sequencing readiness.

  • Experience in PCR method and PCR products for various methods of DNA barcode sequencing.

  • Experience in DNA barcode sequence assembly and analysis using Geneious or similar bioinformatics software and uploading to BOLD and GenBank.

  • Experience in checking sequences using Basic Local Alignment Search Tool (BLAST) and other bioinformatic tools, with independent interpretation of results.

  • Experience in species delimitation, construction of haplotype networks and making maps in R

  • Sound theoretical knowledge and practice in next-generation sequencing (NGS) analysis pipelines, particularly mitochondrial genome assembly and annotation.

  • Ability to troubleshoot next-generation sequencing (NGS) data.

  • Experience in uploading to GenBank and obtaining verified status for organelle genomes

  • Assist in training other research associates in standard lab methodologies and software.

  • Strong ability to maintain accurate and organized records, including lab notebooks, spreadsheets, and database entries.

  • Experience and ability to submit jobs within high-performance computing environments (HPC).

  • Ability to fix complex job submission errors, node failures, and resource contention issues within HPC environments.

  • Experience with Python making use of additional mitochondrial assembly and upload programs, including sequencing coverage plots.

  • Ability to effectively communicate and interact with a variety of people from the public to governmental agencies.

SPECIAL CONDITIONS
  • Job offer is contingent upon satisfactory clearance based on Background Check results.

Pay Transparency Act

Annual Full Pay Range: $75,449 - $121,324 (will be prorated if the appointment percentage is less than 100%)

Hourly Equivalent: $36.13 - $58.11

Factors in determining the appropriate compensation for a role include experience, skills, knowledge, abilities, education, licensure and certifications, and other business and organizational needs. The Hiring Pay Scale referenced in the job posting is the budgeted salary or hourly range that the University reasonably expects to pay for this position. The Annual Full Pay Range may be broader than what the University anticipates to pay for this position, based on internal equity, budget, and collective bargaining agreements (when applicable).

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