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Madrigal is a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), a serious liver disease that can progress to cirrhosis, liver failure, need for liver transplantation and premature mortality. Every member of our Madrigal team is connected by our shared purpose: leading the fight against MASH. Madrigal’s medication, Rezdiffra (resmetirom), is a once-daily, oral, liver-directed THR-β agonist designed to target key underlying causes of MASH. Rezdiffra is the first and only medication approved by both the FDA and European Commission for the treatment of MASH with moderate to advanced fibrosis (F2 to F3). An ongoing Phase 3 outcomes trial is evaluating Rezdiffra for the treatment of compensated MASH cirrhosis (F4c). Our success is driven by our people. We are building a dynamic, inclusive, and high-performing culture that values scientific excellence, operational rigor, and collaboration. To support our continued growth, we are strengthening our workforce strategy to ensure we have the right talent, at the right time, in the right way.

The Senior Director, Market Access, Trade & IDN Analytics leads the analytics agenda supporting Market Access, Trade & Channel, and IDN/institutional account strategy for the MASH portfolio. Reporting to the Head of Commercial Data & Analytics, this leader partners directly with Market Access leadership to build the capabilities that inform payer strategy, channel performance, gross-to-net economics, and institutional account prioritization. The role will be supported by a team of FTE and vendor analytics professionals and serves as a senior thought partner to Commercial leadership on questions where access, channel, and account dynamics intersect. This individual is both a strategic leader and a hands-on problem solver, comfortable shaping the analytic vision while remaining close to the underlying data.

• Own the end-to-end analytics agenda across market access (payer/formulary), trade & channel, and IDN/institutional customer segments for the MASH portfolio.
• Partner with Market Access, Trade & Channel, and Key Account Management leadership to translate business questions into a prioritized analytics roadmap.
• Direct the build-out of analytics capability to understand payer access, perform trade-off analyses, and drive the pull through of existing access through use of varying data assets (SP data, claims, formulary, etc.)
• Lead distribution and specialty pharmacy analytics, including inventory visibility, dispense and time-to-therapy metrics, service-level tracking, and partner scorecards; support specialty pharmacy and distributor QBRs.
• Develop IDN and institutional account analytics to support account segmentation, targeting, and pull-through in GPO, IDN, and limited-distribution settings.
• Leverage analytical use cases across all market access functions and business processes to identify and co-lead build out of advanced analytics & AI capabilities with Commercial Advanced Analytics and our IT AI team.
• Support the build out of data quality and governance standards for third-party data sources, including claims, specialty pharmacy, distributor 852/867 and 3PL data.
• Serve as a senior analytics partner in payer contracting, pricing strategy, and channel strategy discussions, and communicate insights and recommendations to senior Commercial and cross-functional leadership.
• Manage a team of analysts, both internal FTEs and vendors; set goals, manage performance, and coach.

• Typical Degree & Years of Experience Bachelor's degree in a quantitative, business, or related field; advanced degree (MBA, MS) preferred.
• 12+ years of experience in pharmaceutical or biotech commercial analytics, with direct experience leading market access, trade, or channel analytics.
• Demonstrated experience building, leading, and developing analytics teams.
• Hands-on experience with pharma-specific data sources such as claims, specialty pharmacy data, distributor 852/867 data, and syndicated data (e.g., PurpleLabs, IQVIA, Symphony, etc.)
• Working knowledge of gross-to-net, contract, and rebate analytics and the platforms that support them (e.g., IntegriChain, MMIT).
• Preferred Experience supporting specialty or rare disease brands, ideally in a launch or early‑commercialization environment.
• Direct experience with market access advanced analytics (provider control, payer share shift, etc.)
• Direct experience with IDN, GPO, or institutional/limited-distribution account analytics.
• Familiarity with cloud data platforms such as Snowflake or Databricks and with BI tools such as Power BI or Tableau.
• Exposure to AI-enabled or agentic analytics tools in a commercial pharma setting.

• Ability to translate ambiguous business questions into a structured, prioritized analytics agenda.
• Strong executive communication and cross-functional influence with access, channel, and account stakeholders.
• Comfort operating fluidly between strategic framing and detailed, hands-on analysis.
• Proven people leadership, coaching, and team development.

Madrigal’s Total Rewards strategy is based on a biotech industry peer group comparator and is inclusive of base pay, bonus and equity. Our equity offers meaningful opportunity allowing our employees to share in the success they help create. By aligning individual and company performance, we empower employees to think like owners, giving them a stake in the organization. All employees receive equity, which we believe reinforces our ownership culture. Base salary is determined by several factors including the candidate’s qualifications, skills, education, experience, business needs and market demands. As of the date of this posting, a good faith estimate of the current pay scale for this position, applicable to all candidates, is $263,000 - $321,000 per year. We comply with all applicable minimum wage laws. All full-time employees receive equity, which reinforces our ownership culture and offers meaningful opportunity for our employees to share in the success they help create. By aligning individual and company performance, we empower employees to think like owners, giving them a stake in the organization. Full-time employees are also eligible for comprehensive benefits, including flexible paid time off, medical, dental, vision and life/disability insurance, and 401(k) offerings (i.e., traditional, Roth, and employer match) in accordance with applicable plans. We also offer additional voluntary benefits like supplemental life insurance, legal services, and other offerings. In addition, we offer mental health benefits through our Employee Assistance Program for employees and their family. The company also provides other benefits in accordance with applicable federal, state, and local laws.

• flexible paid time off, medical, dental, vision and life/disability insurance, and 401(k) offerings (i.e., traditional, Roth, and employer match) in accordance with applicable plans.
• We also offer additional voluntary benefits like supplemental life insurance, legal services, and other offerings.
• In addition, we offer mental health benefits through our Employee Assistance Program for employees and their family.
• The company also provides other benefits in accordance with applicable federal, state, and local laws.

Madrigal is an Equal Opportunity Employer. All employment is decided on the basis of qualifications, merit, and business need. Applicants will receive consideration for employment without regard to race, ethnicity, color, religion, sex gender identity, sexual orientation, national origin, age, disability, protected veteran or disabled status, or other characteristic protected by applicable federal, state, or local law.

We are committed to providing reasonable accommodations for individuals with disabilities throughout the hiring process. If you need assistance, please contact HR@madrigalpharma.com.