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Microfluidic Engineer Jobs (NOW HIRING)

ONI

Senior Systems Integration Engineer

San Diego, CA · On-site

$130K - $144K/yr

Lead development of microfluidic devices and injection-molded consumables, including tooling ... Manage Bill of Materials (BOMs) and Engineering Change processes (ECO/ECR) using PDM tools ...

ONI

Senior Systems Integration Engineer

San Diego, CA

$130K - $144K/yr

Lead development of microfluidic devices and injection-molded consumables, including tooling ... Manage Bill of Materials (BOMs) and Engineering Change processes (ECO/ECR) using PDM tools ...

AbbVie

Senior Scientist I/II, Instrument

North Chicago, IL

$88K - $120.20K/yr

In this role, you will work at the intersection of engineering, materials science, biology, and innovation. You will develop custom polymer, glass, and silicon microfluidic solutions for a broad ...

ONI

Senior Systems Integration Engineer

San Diego, CA

$130K - $144K/yr

Lead development of microfluidic devices and injection-molded consumables, including tooling ... Manage Bill of Materials (BOMs) and Engineering Change processes (ECO/ECR) using PDM tools ...

Exthymic

Senior Fluidics Engineer

San Diego, CA · On-site

$110.90K - $152.40K/yr

We are scientists, engineers, and operators who have spent our careers inside cell therapy ... Experience with microfluidic chip design and fabrication. * Familiarity with sterile fluid path ...

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$45.5K

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How much do microfluidic engineer jobs pay per year?

As of Jun 3, 2026, the average yearly pay for microfluidic engineer in the United States is $102,878.00, according to ZipRecruiter salary data. Most workers in this role earn between $81,500.00 and $126,500.00 per year, depending on experience, location, and employer.

What is a Microfluidic Engineer job?

A Microfluidic Engineer designs, develops, and optimizes microfluidic systems for applications in biotechnology, healthcare, diagnostics, and research. They work with small-scale fluid dynamics, creating devices that manipulate tiny volumes of liquids for tasks like lab-on-a-chip technology, drug delivery, and chemical analysis. Their role involves material selection, prototyping, testing, and integrating microfluidic systems with sensors and electronics. They often collaborate with biologists, chemists, and engineers to develop innovative solutions for scientific and industrial challenges.

What are the key skills and qualifications needed to thrive in the Microfluidic Engineer position, and why are they important?

To thrive as a Microfluidic Engineer, you need a solid background in engineering, physics, or biomedical sciences, with expertise in fluid dynamics, microfabrication, and device prototyping. Familiarity with CAD software, cleanroom processes, simulation tools like COMSOL Multiphysics, and often a relevant certification or advanced degree are commonly valued. Strong analytical thinking, problem-solving, and collaboration skills are crucial, as projects frequently involve interdisciplinary teams. These competencies are important for successfully designing, developing, and troubleshooting innovative microfluidic devices used in fields like life sciences, diagnostics, and research.

What are typical daily responsibilities for a Microfluidic Engineer?

A Microfluidic Engineer's daily responsibilities often include designing and simulating microfluidic systems, conducting laboratory experiments, analyzing prototype performance, and working closely with biologists, chemists, and other engineers to refine project requirements. They may also spend time fabricating devices in cleanroom environments, documenting results, and troubleshooting technical challenges that arise during development. Collaboration with team members and stakeholders is common, as is the need to stay up-to-date on advancements in fabrication techniques and materials. These activities ensure that innovative and reliable microfluidic solutions are created for applications ranging from medical diagnostics to drug development.
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Microfluidic Engineer jobs near you

Senior Systems Integration Engineer

ONI

San Diego, CA • On-site

$130K - $144K/yr

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Posted 5 days ago

Job description

At ONI, we are driven by a profound mission: to propel scientific discovery and combat diseases by granting everyone the ability to visualize, comprehend, and share the intricate microscopic details of life. Our revolutionary super resolution microscope and fluidic systems stand at the forefront of advancing cellular studies on a molecular level.
We are seeking a versatile Senior Systems Integration Engineer who thrives at the intersection of hardware, software, and biology to lead the technical realization of our next-generation biotech platforms.
Your role at ONI as a Senior Systems Integration Engineer
As a Senior Systems Integration Engineer within the Fluidics Team, you will be the technical "glue" between design and production. You will not only verify that our systems work, but actively participate in the design, prototyping, and manufacturing scale-up of complex biotech hardware. This role requires a unique blend of fluid dynamic knowledge, mechanical design (CAD), automated testing (Python), and a deep understanding of manufacturing processes (injection molding, CNC machining).
Key Responsibilities
System Integration & Verification
  • Lead end-to-end system integration across fluidic systems, consumables, optics, and electronics.
    • >

  • Develop system-level test strategies, integration plans, and verification protocols aligned with product requirements.
    • >

  • Design and execute rigorous V&V protocols to identify technical issues early in the development lifecycle.
    • >

Mechanical Design & Prototyping
  • Design and manufacture test fixtures and prototypes using SolidWorks.
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  • Utilize 3D printing (Resin/FDM), CNC machining, and sheet metal fabrication to accelerate R&D.
    • >

Consumables & Fluidic Systems Development
  • Lead development of microfluidic devices and injection-molded consumables, including tooling oversight, material selection (e.g., PSA, overmolding), and biocompatibility considerations.
    • >

Manufacturing Transfer (NPI)
  • Drive transfer from R&D to manufacturing, ensuring designs are robust, documented and scalable.
    • >

  • Create and maintain Work Instructions (WI), SOPs, and validation documentation (IQ/OQ/PQ).
    • >

  • Manage Bill of Materials (BOMs) and Engineering Change processes (ECO/ECR) using PDM tools (3DXperience).
    • >

Automation & Control
  • Develop automated test frameworks in Python for hardware testing (e.g., leak testing, heat sealing, liquid handling).
    • >

  • Collaborate with the Software team for firmware/software integration and version control (GitHub).
    • >

Risk & Quality Management
  • Maintain and manage dFMEA, pFMEA, and risk register ownership.
    • >

  • Conduct root-cause analysis and failure investigations using HAL logs and data analysis.
    • >

Cross-functional Leadership
  • Work independently to source materials, manage vendors and contractors, and collaborate with Assay, Software, and Production teams to meet product launch milestones.
    • >

Essential skills and qualifications
  • Bachelor's degree in an engineering discipline (Mechanical, Electrical, Optical, or related field).
    • >

  • 5+ years of experience in system integration, hardware development, or complex instrumentation.
    • >
  • Demonstrated experience in testing and integrating systems containing automated liquid handlers, fluidic consumables and high-precision instrumentation.
    • >

  • Deep understanding of fluid dynamics as well as fluidic components, including peristaltic/syringe pumps, solenoid valves, sensors (pressure/flow), and connectors.
    • >

  • Proficiency in 3D CAD for part/assembly design, detailed drawings, and design iteration.
    • >

  • Experience with SolidWorks is strongly preferred, particularly for complex assemblies, production ready drawings, and Product Data Management (PDM) workflows.
    • >

  • Proficiency in Python for test automation and data analysis (Excel/Custom scripts).
    • >

  • Experience developing test methods and executing system-level verification and validation.
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  • Solid understanding of various manufacturing methods, specifically injection molding, assembly, and quality control (e.g., First Article Inspection).
    • >

  • Familiarity with full product development processes (concept to launch) and rigorous technical documentation standards.
    • >

Preferred skills and qualifications
  • Hands-on wet lab experience, with familiarity in biological workflows or assay development.
    • >

  • Experience with embedded systems (e.g., STM32) and integration of PCB-based hardware and firmware.
    • >

  • Knowledge of super-resolution microscopy, optics, and imaging subsystems.
    • >

  • Working knowledge of electronics design tools (e.g., Altium Designer, KiCAD) and hands-on skills such as soldering, and custom cabling.
    • >

  • Experience with sterilization methods (e.g., Gamma, EtO) and materials used in biomedical consumables.
    • >

  • Familiarity with pressure-sensitive adhesives (PSA), overmolding, or microfluidic device fabrication.
    • >

$130,000 - $144,000 a year
At ONI, we understand that a fulfilling career involves more than just challenging work - it's about enjoying a well-rounded experience. When you become a part of our team, you not only contribute to groundbreaking research but also enjoy a range of benefits designed to enhance your life both inside and outside the workplace.
As an equal opportunity employer, we prioritize fairness and respect, ensuring every team member thrives regardless of their background. But that's not all - our perks include:
Competitive Compensation We recognize and reward your talent. Enjoy a competitive salary that reflects your expertise and contributions, ensuring your hard work is recognized.
Flex PTO plus 11 federal holidays and 4 dedicated wellbeing days.
Gym Access via ARE: Sorrento Valley, Torrey Pines, and UTC
401K via ADP
Life Insurance
Medical
Dental
Vision
Perks at Work: Enjoy exclusive discounts and deals through our perks at work program, adding value to your everyday life.
If you are driven by innovation, eager to make a significant impact in the realm of scientific and medical research, and possess the skills and passion we are looking for, we invite you to apply and be a part of our mission to improve our understanding of the details of life.
We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.

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