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Metabolomics Research Jobs (NOW HIRING)

University of Michigan

RESEARCH FELLOW

Ann Arbor, MI · On-site

Targeted metabolomics studies for routine quantitation of well characterized metabolites, or ... Job Detail Job Opening ID 280806 Working Title RESEARCH FELLOW Job Title RESEARCH FELLOW Work ...

Bruker Corporation

Research Associate

Boston, MA · On-site

$62K - $100K/yr

... research and development. All our systems and instruments are designed to improve safety of ... Through a recent partnership with Biocrates, we are extending the services metabolomics and ...

UNAVAILABLE

Research Associate

Boston, MA

$62K - $100K/yr

... research and development. All our systems and instruments are designed to improve safety of ... Through a recent partnership with Biocrates, we are extending the services metabolomics and ...

Bruker

Research Associate

Boston, MA · On-site

$62K - $100K/yr

... research and development. All our systems and instruments are designed to improve safety of ... Through a recent partnership with Biocrates, we are extending the services metabolomics and ...

Bruker Corporation

Research Associate

Boston, MA

$62K - $100K/yr

... research and development. All our systems and instruments are designed to improve safety of ... Through a recent partnership with Biocrates, we are extending the services metabolomics and ...

Baylor College of Medicine

WI · On-site

$54 - $73/hr

The lab is looking for a highly self-motivated Postdoctoral Research Associate with extensive experience in liquid chromatography-MS metabolomics, lipidomics, and drug metabolism. The Postdoctoral ...

Bruker

Title Research Associate

Boston, MA

$62K - $100K/yr

Research Associate Job Locations US-MA-Boston Area Posted Date 1 month ago(8/6/2026 5:56 PM) Req. ... Through a recent partnership with Biocrates, we are extending the services metabolomics and ...

Tamus

Research Specialist

College Station, TX

$5.4K/mo

Metabolomics * Multi-omics integration analyses * Develops and maintains bioinformatics pipelines for data processing and quality control. * Collaborates with biologists, nutrition scientists, and ...

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Metabolomics Research information

What is metabolomics research?

Metabolomics research is the scientific study of small molecules, known as metabolites, within cells, biofluids, tissues, or organisms. This field aims to systematically identify and quantify these metabolites to understand biological processes, disease mechanisms, and responses to environmental changes. Researchers use advanced analytical techniques such as mass spectrometry and nuclear magnetic resonance to profile metabolic changes. The insights from metabolomics can help in biomarker discovery, drug development, and personalized medicine.

What are the key skills and qualifications needed to thrive in metabolomics research?

To thrive in Metabolomics Research, you need a solid background in biochemistry, analytical chemistry, or related life sciences, often supported by a relevant advanced degree. Experience with mass spectrometry, chromatography techniques, and bioinformatics tools such as MetaboAnalyst or XCMS is typically required. Strong analytical thinking, problem-solving, and effective communication skills set top researchers apart. These skills enable precise data interpretation, successful experimental design, and impactful collaboration in multidisciplinary research environments.

What are some common challenges faced in a metabolomics research role, and how can they be addressed?

One of the main challenges in metabolomics research is managing and interpreting large, complex datasets generated by high-throughput analytical techniques such as mass spectrometry or NMR. Ensuring data quality and reproducibility requires meticulous sample preparation and robust quality control procedures. Collaborating closely with bioinformaticians and statisticians is essential to derive meaningful biological insights from the data. Staying updated with evolving analytical technologies and software tools also helps in overcoming technical hurdles and advancing your research.

What is the difference between Metabolomics Research vs Biochemist?

AspectMetabolomics ResearchBiochemist
Required CredentialsMaster's or PhD in Biochemistry, Molecular Biology, or related fieldsMaster's or PhD in Biochemistry or related disciplines
Work EnvironmentLaboratories focusing on metabolite analysis, data interpretation, and biomarker discoveryLaboratories or research settings studying biochemical processes and enzyme functions
Industry UsagePharmaceutical, biotech, academic research, clinical studiesPharmaceutical, healthcare, academic research, food industry

Metabolomics Research primarily focuses on analyzing metabolites and understanding metabolic pathways using advanced analytical techniques, while Biochemists study the chemical processes within and related to living organisms. Both roles require similar educational backgrounds and often work in overlapping industries, but their specific focus and daily tasks differ.

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Metabolomics Research jobs near you
Infographic showing various Metabolomics Research job openings in the United States as of August 2026, with employment types broken down into 1% Internship, 1% As Needed, 84% Full Time, 11% Part Time, 1% Temporary, and 2% Contract. Highlights an 84% Physical, 4% Hybrid, and 12% Remote job distribution.

Scientist, Metabolomics

Alnylam Pharmaceuticals

Cambridge, MA • On-site

$110K - $165K/yr

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Re-posted 17 days ago

Job description

Overview
Alnylam's Translational Research group is seeking a highly motivated Metabolomics Scientist to join our team. We use untargeted and targeted liquid chromatography-tandem mass spectrometry (LC-MS/MS)-based omics and computational biology to support biomarker discovery and target validation efforts for our RNAi-based therapeutics. The successful candidate will have a background in biological sample preparation for endogenous metabolites/lipids, LC-MS/MS operation/troubleshooting, and omics-level data analysis.
This position is onsite and will be primarily located in Cambridge, MA.
Key Responsibilities
  • Design, validate, and apply LC-MS/MS methods for endogenous metabolite and lipid quantification to identify and measure biomarkers, characterize pharmacodynamic activity of novel therapeutic molecules, and answer foundational biological questions.
  • Perform end-to-end metabolite/lipid sample preparation protocols for biofluids, solid tissues, and cultured cells.
  • Operate, maintain, and troubleshoot LC-MS systems as needed.
  • Develop and apply bioinformatics tools for large-scale data processing and statistical analysis.
  • Identify and onboard novel technologies for biomarker measurement and identification.
  • Maintain QC records, analyze data, and document protocols/results in a clearly organized electronic lab notebook.
  • Collaborate with cross-disciplinary and external teams to support preclinical and clinical drug discovery activities.
  • Contribute to preclinical/clinical study design and biomarker strategies for drug candidate programs.
  • Serve as subject matter expert for general questions pertaining to translational biology.
  • Present results at internal/external meetings and author findings in reports/manuscripts.

Qualifications
  • PhD in analytical chemistry, biochemistry, chemical engineering, biological engineering, or related field required, with post-doctoral experience a plus; or MS with 8+ years' experience, preferably in pharma/biotech.
  • Direct experience with triple-quadrupole and high-resolution accurate mass LC-MS/MS-based methods for endogenous metabolite/lipid quantification (ideally with Sciex QTRAP and Thermo Orbitrap systems), including assay development and validation.
  • Experience with metabolite/lipid extraction sample preparation from biofluids, tissues, and/or cultured cells.
  • Experience with relevant omics-based bioinformatics software; familiarity with basic programming languages (e.g. Python or R) and/or AI-based coding tools (e.g. Claude Code or Codex) is a strong plus.
  • Experience with stable isotope tracing and/or metabolic flux analysis is also a plus.
  • A strong publication record and demonstration of successful collaborations.
  • Strong written and oral communication skills.
  • Strong abilities to work both independently and in a team environment.

Intellectual curiosity, a passion for science, critical thinking skills, and a willingness to ask questions.
#LI-JR1
U.S. Pay Range
$110,400.00 - $165,600.00
The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity).
Alnylam's robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together.
Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: https://www.alnylam.com/careers
About Alnylam
We are the leader in RNAi therapeutics - a revolutionary approach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possible and are just at the beginning of what's possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, where an authentic, inclusive culture and breakthrough thinking fuel one another.
At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

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