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Medical Device System Engineer Jobs in California

Mizuho OSI

Systems Engineer, Medical Device

Union City, CA · On-site

$82K - $150K/yr

... Systems Engineer you will be part of a small, agile team; responsible for medical device ... Understand, follow and support Mizuho OSI's internal Quality System policies, procedures and work ...

Mizuho OSI

Systems Engineer, Medical Device

Union City, CA · On-site

$82K - $150K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

... Systems Engineer you will be part of a small, agile team; responsible for medical device ... Understand, follow and support Mizuho OSI's internal Quality System policies, procedures and work ...

Mizuho Osi

Systems Engineer, Medical Device

Union City, CA · On-site

$82K - $150K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

... Systems Engineer you will be part of a small, agile team; responsible for medical device ... Understand, follow and support Mizuho OSI's internal Quality System policies, procedures and work ...

Infotech Spectrum

System Engineer

Sunnyvale, CA · On-site

System Engineer Location : Sunnyvale, CA (Need Locals) Duration : 6+ Months Experience developing ... Experience with MRI and/or radio-therapy applications desirable Familiarity with medical device ...

RESOLVEM USA

Medical Devices System Engineer

Irvine, CA · On-site

$110K - $150K/yr

  • Medical

  • Dental

  • Retirement

  • PTO

This position offers the chance to work with cutting-edge medical device companies, lead impactful ... We are seeking a highly skilled and detail-oriented system engineer to help our customers in design ...

RESOLVEM USA

Medical Devices System Engineer

Irvine, CA · On-site

$110K - $150K/yr

  • Medical

  • Dental

  • Retirement

  • PTO

This position offers the chance to work with cutting-edge medical device companies, lead impactful ... We are seeking a highly skilled and detail-oriented system engineer to help our customers in design ...

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Medical Device Assembler

San Clemente, CA · On-site

$22.10/hr

  • Medical

  • Dental

  • Life

  • Retirement

Support engineering tests by executing defined test methods * Record and maintain documentation as ... by QA systems * Assist in generating or editing SOPs and DHRs for development activities

AngioSafe

Medical Device R&D Engineer

San Jose, CA · On-site

$115K - $175K/yr

Minimum 5 years of medical device R&D experience * Hands-on catheter prototyping and testing ... Experience with document control systems and engineering change documentation * Strong hands-on ...

Infotech Spectrum

System Engineer

Sunnyvale, CA · On-site

System Engineer Location : Sunnyvale, CA (Need Locals) Duration : 6+ Months • Experience ... medical device hazard analysis and design of mitigations for risk highly desirable • Ability to ...

AngioSafe

Medical Device R&D Engineer

San Jose, CA · On-site

$115K - $175K/yr

Minimum 5 years of medical device R&D experience * Hands-on catheter prototyping and testing ... Experience with document control systems and engineering change documentation * Strong hands-on ...

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All JobsMedical Device System Engineer JobsMedical Device System Engineer Jobs in California

Medical Device System Engineer information

See California salary details

$52.8K

$125.5K

$164.8K

How much do medical device system engineer jobs pay per year?

As of Aug 16, 2026, the average yearly pay for medical device system engineer in California is $125,549.00, according to ZipRecruiter salary data. Most workers in this role earn between $96,700.00 and $154,900.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a medical device system engineer?

A Medical Device System Engineer requires a strong background in systems engineering, biomedical engineering, or a related field, along with expertise in medical device development and regulatory requirements. Familiarity with design tools (such as CAD and MATLAB), medical device quality standards (like ISO 13485), and risk management processes is highly valuable. Effective communication, problem-solving abilities, and teamwork distinguish candidates in collaborative, cross-disciplinary environments. These competencies are crucial for ensuring safe, innovative, and compliant medical devices that meet both user needs and regulatory expectations.

What are typical daily tasks and responsibilities for a medical device system engineer?

Medical Device System Engineers are often responsible for designing, testing, and integrating complex medical devices while ensuring adherence to regulatory standards and safety requirements. Their daily tasks can include drafting system architectures, collaborating with electrical, mechanical, and software teams, conducting risk analyses, reviewing technical documentation, and supporting troubleshooting efforts during product development. They also frequently attend cross-functional meetings to align project timelines and discuss design improvements. This role provides a dynamic balance of hands-on engineering, project management, and regulatory compliance, making it ideal for individuals who enjoy challenging, mission-driven work in healthcare technology.

What is a medical device system engineer?

A Medical Device System Engineer is responsible for designing, developing, and integrating complex medical device systems. They work across multiple engineering disciplines, including hardware, software, and regulatory compliance, to ensure that medical devices meet quality and safety standards. Their role involves risk analysis, system requirements definition, and verification and validation testing. They collaborate with cross-functional teams, including mechanical, electrical, and software engineers, as well as regulatory and clinical experts. Ultimately, they help bring safe and effective medical technologies to market.

What are the most commonly searched types of Medical Device System Engineer jobs in California?

The most popular types of Medical Device System Engineer jobs in California are:

What are popular job titles related to Medical Device System Engineer jobs in California?

For Medical Device System Engineer jobs in California, the most frequently searched job titles are:

What job categories do people searching Medical Device System Engineer jobs in California look for?

The top searched job categories for Medical Device System Engineer jobs in California are:

Medical Device System Engineer jobs near you
Infographic showing various Medical Device System Engineer job openings in California as of August 2026, with employment types broken down into 63% Full Time, 6% Temporary, and 31% Contract. Highlights an 97% In-person, and 3% Hybrid job distribution, with an average salary of $125,549 per year, or $60.4 per hour.

Senior Software Engineer - Medical Device (Onsite - Irvine, CA) Possible Temp-to-Hire

Pharmavise

Irvine, CA • On-site

$130K - $172K/yr

Contractor

Re-posted yesterday

Job description


Our F500 Medical Device client has an exciting opportunity for a Senior Software Engineer.
Job Summary:
We are seeking a skilled Senior Software Engineer to join the Client's Urology team. In this role, you will be responsible for technical activities related to the customization and validation of the Android Operating System (version 5) deployed within a Class III medical device. This role bridges software engineering, cybersecurity, and medical device product integration for a commercial product. The successful candidate will assess, modify, and harden the Android OS to close cybersecurity gaps, adapt critical applications for compatibility, and perform OS-level verification and validation in alignment with regulated product development standards.
This role will work closely with cybersecurity, systems, and quality engineers to ensure system integrity, compliance, and reliable performance of the Android-based platform within the medical device system.
Responsibilities:
• Analyze and modify Android OS (v5) source to address identified cybersecurity vulnerabilities and compliance gaps.
• Implement OS-level patches, configuration changes, and security controls consistent with medical device cybersecurity guidance (FDA premarket & post market cybersecurity, and EU MDCG ).
• Manage integration of third-party libraries and drivers while maintaining software traceability and regulatory documentation.
• Adapt and refactor existing applications to ensure compatibility with the custom Android OS as needed.
• Optimize interprocess communication, resource management, and hardware interface behaviors in the updated OS environment.
• Collaborate with application developers to test and validate functionality per intended use.
• Conduct OS-level verification and validation per IEC 62304 and internal design control SOPs
• Support risk analysis and mitigation activities per ISO 14971 and internal software QMS SOPs.
• Contribute to software documentation, including software architecture, verification plans, test protocols, and traceability matrices.
• Participate in technical reviews and audits to ensure software compliance with applicable standards.
• Work in close coordination with cybersecurity, software, design quality, and system engineering teams to ensure secure and reliable system operation.
• Support integration testing and root cause analysis of OS-related issues.
Job Requirements:
• Bachelor's or master's degree in computer engineering, computer science, electrical engineering, or a related field.
• 7+ years of professional software engineering experience, with at least 3 years in Android OS development or customization.
• Hands-on experience with AOSP, Android build systems, and kernel-level modification.
• Strong understanding of embedded systems, Linux internals, and Android application frameworks.
• Proven experience in regulated environments (medical device, aerospace, automotive, or defense).
• Working knowledge of IEC 62304, ISO 14971, IEC 60601, and other regulations.
• Familiarity with cybersecurity risk assessment, threat modeling, and vulnerability remediation in embedded platforms.
Preferred Qualifications
• Experience with Android OS version 5 or legacy Android platforms in long-lifecycle products.
• Strong debugging, profiling, and reverse-engineering skills.
• Prior experience supporting device certification and regulatory submissions.
• Excellent communication and documentation skills for technical and compliance deliverables.
Other Details:
• Schedule: 08:00:AM - 04:30:PM
• Contract Length: 12 Months with possible extension
• Work Set-Up: Hybrid in Arbor Lakes, MN
• Start Date: 1/5/2026

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