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Mechanical Engineering Startup Jobs in Oregon (NOW HIRING)

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Staff Engineer, Data Center

Hillsboro, OR · Hybrid

Lead commissioning activities including startup, integrated systems testing, and operational ... Bachelor's degree in Engineering, Mechanical Engineering, Electrical Engineering, Construction ...

LinkedIn

Staff Engineer, Data Center

Hillsboro, OR · On-site

Lead commissioning activities including startup, integrated systems testing, and operational ... Bachelor's degree in Engineering, Mechanical Engineering, Electrical Engineering, Construction ...

AAON, Inc.

Manager, Controls Engineering

Redmond, OR · On-site

$88K - $114K/yr

Support manufacturing, commissioning, startup activities, and escalated field issues. * Drive ... Requires a Bachelor's degree in Electrical Engineering, Controls Engineering, Mechanical ...

AAON, Inc.

Manager, Controls Engineering

Redmond, OR · Hybrid

$88K - $114K/yr

Support manufacturing, commissioning, startup activities, and escalated field issues. * Drive ... Requires a Bachelor's degree in Electrical Engineering, Controls Engineering, Mechanical ...

Danone

Plant Industrialization Engineer

Portland, OR · On-site

$80K - $110K/yr

Support equipment commissioning, startup, validation, and qualification activities. * Ensure ... Bachelor's degree in Mechanical Engineering, Industrial Engineering, Manufacturing Engineering ...

Danone

Project Process Engineer

Portland, OR · Hybrid

$80K - $110K/yr

Support equipment commissioning, startup, validation, and qualification activities. * Ensure ... Bachelor's degree in Mechanical Engineering, Industrial Engineering, Manufacturing Engineering ...

Danone

Project Process Engineer

Eugene, OR · Hybrid

$80K - $110K/yr

Support equipment commissioning, startup, validation, and qualification activities. * Ensure ... Bachelor's degree in Mechanical Engineering, Industrial Engineering, Manufacturing Engineering ...

Danone

Project Process Engineer

Portland, OR · Hybrid

$80K - $110K/yr

Support equipment commissioning, startup, validation, and qualification activities. * Ensure ... Bachelor's degree in Mechanical Engineering, Industrial Engineering, Manufacturing Engineering ...

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Showing results 21-40

All JobsMechanical Engineering Startup JobsMechanical Engineering Startup Jobs in Oregon

Mechanical Engineering Startup information

See Oregon salary details

$48.1K

$108.8K

$176K

How much do mechanical engineering startup jobs pay per year?

As of Aug 9, 2026, the average yearly pay for mechanical engineering startup in Oregon is $108,771.00, according to ZipRecruiter salary data. Most workers in this role earn between $86,200.00 and $133,700.00 per year, depending on experience, location, and employer.

What is a mechanical engineering startup?

A mechanical engineering startup is a new business venture focused on developing, designing, or manufacturing products and solutions that leverage the principles of mechanical engineering. These startups typically work on innovations in areas such as robotics, manufacturing equipment, automotive components, energy systems, or consumer devices. They often aim to bring new technologies to market, solve industry problems, or improve existing mechanical systems. Mechanical engineering startups can range from small teams prototyping in a garage to larger groups with significant funding and facilities. Their success often depends on technical expertise, creative problem-solving, and the ability to rapidly iterate on product designs.

What are some common challenges mechanical engineers face when working in a startup environment?

Mechanical engineers in startups often encounter challenges such as limited resources, rapidly shifting project priorities, and the need to wear multiple hats. Unlike larger organizations, startups may lack specialized teams, so engineers may need to handle a mix of design, prototyping, testing, and even some business or customer-facing tasks. The fast-paced environment can be rewarding, but also demands adaptability, creative problem-solving, and excellent time management skills. Collaboration with colleagues from different backgrounds is frequent, fostering innovation but also requiring strong communication and flexibility.

What are the key skills and qualifications needed to thrive in a mechanical engineering startup, and why are they important?

To thrive in a mechanical engineering startup, you need a solid grounding in mechanical design, problem-solving, and prototyping, typically supported by a mechanical engineering degree. Proficiency with CAD software (such as SolidWorks or AutoCAD), rapid prototyping tools, and familiarity with industry standards or certifications (like FE or PE) are highly valued. Strong adaptability, entrepreneurial mindset, and effective teamwork skills help individuals excel in the dynamic and resource-constrained environment of a startup. These abilities are crucial for driving innovation, efficiently bringing products to market, and overcoming the unique challenges faced by early-stage companies.

What is the difference between Mechanical Engineering Startup vs Mechanical Engineer?

AspectMechanical Engineering StartupMechanical Engineer
CredentialsBachelor's or Master's in Mechanical Engineering, relevant certificationsBachelor's or Master's in Mechanical Engineering, professional licensure often preferred
Work EnvironmentFast-paced, innovative, often small teams, dynamic projectsStructured, corporate or industrial settings, project-based, collaborative
Employer & IndustryStartups in tech, manufacturing, or product developmentEstablished companies, manufacturing, automotive, aerospace

Mechanical Engineering Startup roles focus on innovation, versatility, and rapid project execution within small teams, often requiring a broad skill set. Mechanical Engineers in established firms work on well-defined projects with structured processes. Both roles require similar educational backgrounds but differ in work environment and project scope.

What are popular job titles related to Mechanical Engineering Startup jobs in Oregon? For Mechanical Engineering Startup jobs in Oregon, the most frequently searched job titles are:
What job categories do people searching Mechanical Engineering Startup jobs in Oregon look for? The top searched job categories for Mechanical Engineering Startup jobs in Oregon are:
Mechanical Engineering Startup jobs near you
Infographic showing various Mechanical Engineering Startup job openings in Oregon as of August 2026, with employment types broken down into 90% Full Time, 5% Part Time, 4% Contract, and 1% Nights. Highlights an 86% Physical, 4% Hybrid, and 10% Remote job distribution, with an average salary of $108,771 per year, or $52.3 per hour.

Senior Engineer - Microfluids and Perfusion Interfaces

e184

Portland, OR • On-site

$110K - $152K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Re-posted 10 days ago

Job description

About us
e184 is a biotechnology research company dedicated to overcoming the limits of human biology. One of our programs in reproductive technologies develops ectogenesis - the ability to support human development outside the body - to expand reproductive freedom and redefine what is possible in medicine. Our mission is to remove the biological constraints that limit who can safely carry a pregnancy, enabling new pathways to parenthood for individuals facing medical risk, infertility, or physiological barriers to gestation.
We operate at the intersection of biology, engineering, and computational science, building integrated platforms that combine advanced tissue models, adaptive culture systems, and automated experimental workflows to understand and recreate the conditions required for healthy human gestation beyond the uterus.
Role overview
As a Senior Engineer at e184, you will lead the design and development of microfluidic and perfusion-based systems that enable long-term maintenance of complex cell and tissue cultures. Your work will focus on engineering interfaces that precisely control media exchange, gas delivery, waste removal, and fluid dynamics to recreate physiologically relevant environments over extended culture periods.
You will own the development of integrated culture hardware from concept through experimental validation, working closely with biologists and computational teams to translate biological requirements into robust engineering solutions. This is a highly hands-on, leadership role for an engineer or experimental scientist who thrives at the intersection of bioengineering and developmental biology in a fast-moving startup environment where device performance directly determines experimental success.
What you'll do:
  • Lead perfusion system development: Design and build microfluidic and perfusion platforms that support long-term cell and tissue culture through controlled nutrient delivery, gas exchange, and waste management.
  • Engineer culture interfaces: Develop biocompatible fluidic architectures and culture chambers that maintain stable physiological conditions while enabling imaging, sampling, and experimental manipulation.
  • Optimize fluid and gas transport: Model and experimentally validate flow dynamics, oxygenation, and mass transport to ensure stable culture environments across varying developmental stages and tissue scales.
  • Prototype and iterate rapidly: Design, fabricate, and test devices using microfabrication and rapid prototyping approaches (e.g., CNC machining, laser cutting, soft lithography, additive manufacturing), iterating based on biological performance.
  • Collaborate across disciplines: Work closely with developmental biologists to translate biological constraints into engineering specifications and with software/data teams to integrate monitoring and experimental control systems.

Core requirements:
  • PhD or MS with significant experience in Bioengineering, Mechanical Engineering, Chemical Engineering, Biomedical Engineering, or a related field
  • Demonstrated experience designing or operating microfluidic or perfusion-based culture systems
  • Strong understanding of fluid dynamics, mass transport, and gas exchange in biological systems
  • Hands-on experience with device prototyping and experimental validation
  • Ability to independently drive complex technical projects from concept to implementation
  • Comfortable working in a fast-paced, iterative startup environment
  • Strong organizational and documentation skills

You'll stand out with:
  • Experience working with mammalian cell culture or biological interfaces
  • Experience developing long-term perfusion or organ-on-chip culture systems
  • Background in microphysiological systems, tissue engineering, or bioreactor design
  • Experience designing oxygenation or gas exchange interfaces for biological systems
  • Microfabrication experience (soft lithography, PDMS devices, micromachining, microfluidic bonding techniques)
  • Experience integrating sensors, automation, or closed-loop control systems
  • Prior startup or early-stage technology development experience

Why e184?
  • Unrivaled impact: Your work directly enables technology that transforms human fertility and reproductive medicine.
  • Full-spectrum growth: Gain exposure to the entire lifecycle of discovery. From screening to mechanistic validation.
  • Best of both worlds: Experience the creative chaos of an early-stage startup with the stability of a well-capitalized company.
  • Elite collaboration: Work alongside a world-class team who are as driven as you are.

The perks
  • Competitive salary + equity participation is considered
  • State-of-the-art facility in Portland metro area
  • Comprehensive Medical, Dental, Vision, and 401(k) with company match
  • 20 days PTO + 11 paid holidays

Disclaimer
The above job description is intended to describe the general nature and level of work being performed by individuals assigned to this position. It is not intended to be an exhaustive list of all duties, responsibilities, and skills required. Responsibilities and duties may change or be adjusted to meet the needs of the company, and additional duties may be assigned as necessary. The job description is subject to change at any time at the discretion of e184.
We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses and identifying potential inconsistencies or verification signals in application materials based on available information. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.

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