It Risk Manager Jobs in Denver, CO (NOW HIRING)

Every team member at Biodesix has the potential to impact our business and our patients, providers, and partners. Even our company logo includes a “thumbprint” – a visual reminder that encourages all team members to put their fingerprints on our future. Explore our openings below and see if your next role is here with Team Biodesix. Thank you for considering us in your search.

Senior Technology & Business Risk Manager

Louisville, CO

863-090051

1

Senior Technology & Business Risk Manager

Biodesix is a leading diagnostic solutions company, driven to improve clinical care and outcomes for patients. Biodesix Diagnostic Tests support clinical decisions to expedite personalized care and improve outcomes for patients with lung disease. Biodesix Development Services enable the world’s leading biopharmaceutical, life sciences, and research institutions with scientific, technological, and operational capabilities that fuel the development of diagnostic tests, tools, and therapeutics.

Transform patient care and improve outcomes through personalized diagnostics that are timely, accessible, and address immediate clinical needs.

A world where patient diseases are conquered with the guidance of personalized diagnostics.

The Senior Technology & Business Risk Manager is responsible for leading enterprise technology risk management, business continuity, governance, compliance coordination, and operational resilience activities across the organization. This role oversees risk assessment processes, business continuity planning, control governance, third‑party risk management, audit readiness, and technology risk initiatives that support business operations, cybersecurity objectives, regulatory compliance, and organizational growth. The position partners closely with Infrastructure Engineering, Cybersecurity, Software Development, Business Intelligence, Compliance, Legal, Quality, and business stakeholders to ensure risks are identified, evaluated, communicated, and appropriately mitigated. This position is designed for a hands‑on technology risk leader capable of assessing cybersecurity, infrastructure, operational, and business risks while helping mature enterprise governance, risk management, and operational resilience programs. The successful candidate must be comfortable operating in a highly technical environment and actively participating in risk assessments, audits, technology reviews, business continuity planning, vendor risk evaluations, control design discussions, and operational resilience initiatives.

• Lead enterprise-wide risk identification, assessment, prioritization, mitigation, and reporting activities across technology and business domains.
• Maintain and continuously improve the enterprise risk register, risk methodologies, scoring models, and governance processes
• Facilitate cross-functional risk assessments involving cybersecurity, infrastructure, applications, cloud technologies, data protection, operational processes, and third‑party services
• Establish risk metrics, key risk indicators (KRIs), dashboards, and executive reporting processes.
• Coordinate risk review activities with business leaders and IT stakeholders to ensure risk ownership and mitigation accountability
• Support risk‑informed decision‑making throughout technology and business initiatives
• Partner with business leaders to identify, assess, and monitor operational, strategic, regulatory, and enterprise risks beyond traditional technology domains
• Drive enterprise risk governance through regular risk reviews, executive reporting, and cross‑functional governance committees

• Partner with Infrastructure Engineering and Cybersecurity teams to evaluate technical risks, control effectiveness, and remediation strategies
• Assess enterprise risks associated with emerging technologies, including Artificial Intelligence (AI), automation, cloud‑native platforms, and evolving digital capabilities
• Support governance activities aligned with NIST CSF, NIST RMF, ISO 27001, SOC 2, HIPAA, SOX and related frameworks
• Assist with root cause analysis, risk investigations, control reviews, and corrective action planning
• Conduct and lead technology risk assessments involving infrastructure, cloud services, enterprise applications, identity and access management, cybersecurity controls, endpoint technologies, and operational technology environments
• Stay current with emerging cybersecurity threats, regulatory developments, risk management practices, and technology trends

• Lead development and continuous improvement of the Business Continuity Program
• Conduct Business Impact Assessments (BIAs) and recovery planning activities across business functions
• Coordinate tabletop exercises, continuity testing, and resilience validation activities
• Partner with Infrastructure and Security teams to ensure Disaster Recovery capabilities support business recovery objectives
• Evaluate operational resiliency risks involving critical business processes, vendors, and technology dependencies
• Support incident response reviews and lessons‑learned activities following significant operational disruptions
• Coordinate responses to customer security questionnaires, technology due diligence activities, and third‑party assurance requests

• Coordinate readiness activities for internal and external audits including SOC 2, HIPAA, ISO 27001, SOX, and related assessments
• Partner with business and IT teams to collect audit evidence, validate controls, and track remediation activities
• Support vendor risk assessments, third‑party reviews, and ongoing vendor monitoring activities
• Assist with policy development, control governance, and risk‑related training initiatives
• Monitor evolving regulatory requirements impacting technology, cybersecurity, privacy, and operational risk programs
• Maintain documentation supporting governance, compliance, continuity, and risk management activities
• Partner with Finance, Internal Audit, and business stakeholders to support SOX IT General Controls (ITGCs), application controls, control testing, remediation activities, and audit readiness efforts
• Evaluate technology, cybersecurity, and operational control effectiveness and recommend improvements to reduce organizational risk exposure

• Drive maturity improvements across enterprise risk, business continuity, and governance programs
• Develop and maintain risk management procedures, methodologies, standards, and documentation
• Drive accountability through governance reviews, risk reporting, mitigation tracking, and issue escalation processes
• Support audit readiness and control effectiveness activities within regulated environments
• Provide enterprise leadership by influencing cross‑functional teams, facilitating governance forums, and driving accountability for organizational risk management activities
• Foster a collaborative, risk‑aware, and business‑focused culture across the organization
• Oversee the enterprise technology policy governance process, including policy lifecycle management, periodic reviews, and alignment with regulatory and business requirements

• Bachelor's degree in Information Technology, Information Systems, Cybersecurity, Computer Science, Engineering, Risk Management, or related technical field
• 8+ years of progressive experience in IT Risk Management, Cybersecurity Governance, Enterprise Risk Management, Information Security, Internal IT Audit, GRC, or related disciplines
• 5+ years of leadership experience leading enterprise risk, cybersecurity governance, business continuity, compliance, or technology risk programs
• Experience conducting enterprise technology risk assessments and control evaluations
• Demonstrated experience assessing enterprise technology environments, including infrastructure, cloud platforms, cybersecurity technologies, identity and access management, endpoint technologies, and enterprise applications
• Experience implementing or supporting frameworks such as NIST CSF, NIST RMF, ISO 27001, COBIT, SOX ITGC, HIPAA Security Rule, SOC 2, HITRUST, or similar frameworks
• Demonstrated ability to lead enterprise risk management, business continuity, governance, or cybersecurity risk programs
• Strong organizational skills and ability to balance strategic planning with hands‑on execution
• Experience influencing business and technology leaders regarding risk decisions
• Strong analytical and problem‑solving capabilities involving technology, cybersecurity, operational, and business risks
• Demonstrated understanding of enterprise infrastructure, cloud platforms, identity and access management, endpoint technologies, data protection, and cybersecurity controls
• Comfortable participating in technical reviews, architecture discussions, risk assessments, and remediation planning
• Ability to evaluate technical control effectiveness and communicate risk implications to leadership
• Strong written and verbal communication skills with executive‑level presentation abilities
• Ability to communicate technical risk concepts to both technical and non‑technical audiences
• Collaborative mindset with the ability to influence stakeholders across multiple business functions
• Experience operating within regulated or compliance‑focused environments
• Familiarity with healthcare, laboratory, biotechnology, or highly regulated industry frameworks
• Experience presenting risk assessments and recommendations to executive leadership
• CISSP, CISM, CRISC, CGRC, CISA, CBCP, PMP, or equivalent certifications, preferred
• Experience with ServiceNow GRC, Archer, AuditBoard, Drata, or similar platforms , preferred
• Experience within healthcare, diagnostics, biotechnology, pharmaceutical, or regulated industries , preferred
• Experience supporting AI governance, AI risk management, or emerging technology oversight , preferred

• Annual Base Salary Range $145,000 - $160,000
• Discretionary Bonus opportunity
• Comprehensive health coverage: Medical, Dental, and Vision
• Insurance: Short/Long Term Disability and Life Insurance
• 120 hours of annual vacation
• 72 hours of paid sick time off
• 11 paid holidays + 3 floating holidays
• Employee Assistance Program
• Voluntary Benefits
• Employee recognition program

Individual base compensation is based on various factors unique to each candidate, including skill set, experience, qualifications, and other job‑related aspects.

Biodesix is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or veteran status.

We are committed to ensuring an inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or veteran status.

If you are an individual with a disability and require a reasonable accommodation to use our online system to search and/or apply for a position, please send us an email atcareers@biodesix.com.