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It Infrastructure Jobs in Wisconsin (NOW HIRING)

nVent

IT Infrastructure Manager II

Madison, WI · On-site

We are in search of a proactive and knowledgeable IT Infrastructure Manager to lead the development, implementation, and operational excellence of our core infrastructure systems. Responsibilities ...

nVent

IT Infrastructure Manager II

New Berlin, WI · On-site

We are in search of a proactive and knowledgeable IT Infrastructure Manager to lead the development, implementation, and operational excellence of our core infrastructure systems. Responsibilities ...

King Juice Company

IT Intern

Milwaukee, WI · On-site

$14.75 - $19.75/hr

Strong interest in IT infrastructure, servers, networking, and hands-on hardware support. * Working knowledge of computer hardware components and ability to diagnose common hardware issues. * Basic ...

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It Infrastructure information

See Wisconsin salary details

$11

$57

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How much do it infrastructure jobs pay per hour?

As of Aug 9, 2026, the average hourly pay for it infrastructure in Wisconsin is $57.79, according to ZipRecruiter salary data. Most workers in this role earn between $48.03 and $65.53 per hour, depending on experience, location, and employer.

What are some common challenges IT infrastructure professionals face when managing both on-premises and cloud-based systems?

IT Infrastructure professionals often encounter challenges in ensuring seamless integration between on-premises and cloud environments, particularly around security, data consistency, and network performance. Managing hybrid systems requires staying updated on different platforms, monitoring for vulnerabilities, and troubleshooting issues that can arise from system incompatibilities. Additionally, balancing resource allocation and maintaining compliance with organizational and regulatory standards are ongoing concerns. Effective communication and collaboration with cross-functional teams, such as cybersecurity and application development, are essential to address these challenges successfully.

What is the difference between It Infrastructure vs Network Administrator?

AspectIT InfrastructureNetwork Administrator
Required CredentialsCertifications like CompTIA A+, Network+, Cisco CCNACertifications like CompTIA Network+, Cisco CCNA
Work EnvironmentData centers, server rooms, enterprise IT departmentsOffice networks, server rooms, enterprise environments
Employer & Industry UsageIT departments across various industries managing overall infrastructureOrganizations managing and maintaining network systems
Common Search & ComparisonOften compared for roles in IT support and infrastructure setupFocuses on network management and security

While both roles are integral to IT operations, IT Infrastructure encompasses a broader scope including servers, storage, and network systems, whereas Network Administrators specifically focus on managing and maintaining network connectivity and security within an organization.

What are the key skills and qualifications needed to thrive as an IT infrastructure specialist, and why are they important?

To thrive as an IT Infrastructure Specialist, you need a solid understanding of network architecture, server administration, cybersecurity principles, and typically a degree in computer science or a related field. Familiarity with tools such as VMware, Microsoft Windows Server, Linux systems, and certifications like CompTIA Network+, Cisco CCNA, or Microsoft Certified: Azure Administrator are commonly required. Strong problem-solving abilities, effective communication, and adaptability help professionals excel in troubleshooting and collaborating across departments. These skills and qualifications ensure reliable, secure, and efficient IT environments that support organizational operations.

What is IT infrastructure?

IT infrastructure refers to the combination of hardware, software, networks, data centers, facilities, and related equipment used to develop, test, operate, monitor, manage, and support information technology services. It forms the backbone that enables organizations to deliver IT solutions and services to their employees, customers, and partners. Effective IT infrastructure ensures systems are reliable, scalable, and secure, supporting the organization's business goals and operations.
What are the most commonly searched types of It Infrastructure jobs in Wisconsin? The most popular types of It Infrastructure jobs in Wisconsin are:
What are popular job titles related to It Infrastructure jobs in Wisconsin? For It Infrastructure jobs in Wisconsin, the most frequently searched job titles are:
What job categories do people searching It Infrastructure jobs in Wisconsin look for? The top searched job categories for It Infrastructure jobs in Wisconsin are:
It Infrastructure jobs near you
Infographic showing various It Infrastructure job openings in Wisconsin as of August 2026, with employment types broken down into 67% Full Time, and 33% Part Time. Highlights an 100% In-person job distribution, with an average salary of $120,197 per year, or $57.8 per hour.

Director, IT Infrastructure

Arrowhead Pharmaceuticals

Madison, WI

Full-time

Re-posted 14 days ago

Job description

Arrowhead Pharmaceuticals, Inc. (Nasdaq ARWR) is a commercial stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Arrowhead's RNAi-based therapeutics leverage this natural pathway of gene silencing.

Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, typically characterized by the overproduction of one or more proteins that are involved with disease. The depth and versatility of our RNAi technologies enables us to potentially address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise addressable by small molecules and biologics. Arrowhead is leading the field in bringing the promise of RNAi to address diseases outside of the liver, and our clinical pipeline includes disease targets in the liver and lung with a promising pipeline of preclinical candidates.

Arrowhead's corporate headquarters is in Pasadena, CA with research and development teams in Madison, WI & San Diego, CA, and a state of the art manufacturing facility in Verona, WI. Our employees are nimble, science-driven innovators who are collaborating to bring new therapies to patients in need.

The Position

The Director of IT Infrastructure is a leadership role responsible for the strategy, design, implementation, and ongoing operations of the company's enterprise IT infrastructure. This leader will oversee a geographically distributed environment spanning on-premises and public cloud platforms (Microsoft Azure and Amazon Web Services). The Director will lead a team of infrastructure staff to support business needs, drive modernization initiatives, and ensure the reliability and scalability of all infrastructure services in alignment with pharmaceutical industry standards.

This role is based onsite 5 days a week from one of Arrowhead's office locations.

Responsibilities

  • Define and execute a multi-year IT infrastructure roadmap aligned with corporate growth objectives and digital transformation priorities.
  • Lead, mentor, and develop a high-performing infrastructure team across multiple sites.
  • Partner with the IS leadership and business stakeholders to align infrastructure investments with organizational priorities and compliance requirements.
  • Establish and manage infrastructure budgets, vendor contracts, and technology refresh cycles.
  • Develop and communicate infrastructure KPIs, SLAs, and operational metrics to IS leadership.
  • Define and execute a multi-year IT infrastructure roadmap aligned with corporate growth objectives and digital transformation priorities.
  • Oversee the design, deployment, and lifecycle management of virtualization infrastructure across all company locations.
  • Manage a Microsoft Active Directory environment
  • Drive hybrid cloud strategy and operations across Azure and AWS, optimizing workload placement, cost, and performance.
  • Ensure high availability, disaster recovery, and business continuity capabilities for all critical infrastructure components.
  • Oversee network infrastructure including LAN/WAN and SD-WAN connectivity across all company sites and cloud tenants.
  • Oversee server patching and configuration management standards across the enterprise.
  • Lead capacity planning and performance monitoring to ensure infrastructure scalability in support of business growth.
  • Ensure all infrastructure platforms and processes comply with regulatory requirements as applicable.
  • Support internal and external audits by providing documentation, evidence, and technical guidance related to infrastructure controls.
  • Maintain and test disaster recovery and incident response plans in partnership with IS and business teams.
  • Lead infrastructure-related projects from inception through delivery, including consolidations, cloud migrations, and site expansions.
  • Manage relationships with key technology vendors and MSPs, negotiating contracts and ensuring service delivery accountability.
  • Evaluate and recommend emerging technologies that drive operational efficiency and cost reduction.

Requirements

  • Bachelor's degree in Computer Science, Information Systems, Information Technology, or a related field.
  • 10+ years of progressive IT infrastructure experience, with at least 4 years in a senior leadership or director-level role.
  • Deep hands-on expertise with virtualization platforms (VMware, Nutanix, Hyper-V).
  • Demonstrated experience managing Microsoft Active Directory.
  • Strong working knowledge of AWS and Azure — architecture, operations, cost management, and security.
  • Experience managing multi-site enterprise IT environments in a regulated industry.
  • Proven track record of building, leading, and developing high-performing infrastructure teams.
  • Strong understanding of network architecture, security principles, and ITIL-based service management frameworks.
  • Experience with infrastructure compliance frameworks relevant to pharma/biotech (GxP, SOX, HIPAA).

Preferred

  • Current or previous industry certifications such as VMware VCP/VCAP, Azure Administrator/Architect, AWS Solutions Architect, or ITIL v4.
  • Experience with infrastructure-as-code tools such as Terraform, Ansible, or Bicep.
  • Experience supporting laboratory and manufacturing IT environments (OT/IT convergence) within a pharmaceutical or life sciences setting.
  • Strategic thinking and the ability to translate business needs into scalable infrastructure solutions.
  • Strong communication skills - able to present complex technical topics clearly to non-technical audiences.
  • Exceptional organizational and prioritization skills in a fast-paced, regulated environment.
  • Collaborative leadership style with a strong emphasis on team development and cross-functional partnership.
  • Data-driven decision-making and a continuous improvement mindset.
Wisconsin pay range
$190,000—$210,000 USD
California pay range
$210,000—$230,000 USD

Arrowhead provides competitive salaries and an excellent benefit package.

Candidates must have current, valid authorization to work in the country where this role is located.

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