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Internship Downstream Process Development Scientist Jobs in Madison, WI

Illumina, Inc.

Sr Biochemistry Scientist

Madison, WI · On-site

$92K - $126K/yr

  • Medical

  • Dental

  • Vision

  • Retirement

  • PTO

You are the Senior Biochemistry Scientist Illumina is looking for in joining our Test Method ... Work closely with Quality Control, Manufacturing, Quality Assurance, Process Development, and ...

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All JobsDownstream Process Development Scientist JobsInternship Downstream Process Development Scientist JobsInternship Downstream Process Development Scientist Jobs in Madison, WI

Internship Downstream Process Development Scientist information

See Madison, WI salary details

$20

$38

$62

How much do internship downstream process development scientist jobs pay per hour?

As of Aug 17, 2026, the average hourly pay for internship downstream process development scientist in Madison, WI is $38.96, according to ZipRecruiter salary data. Most workers in this role earn between $28.56 and $46.49 per hour, depending on experience, location, and employer.

What does an internship downstream process development scientist do?

An Internship Downstream Process Development Scientist works in the biopharmaceutical industry, assisting with the development and optimization of processes that purify biological products such as proteins, antibodies, or vaccines after they are produced by cells. Their role often involves supporting laboratory experiments, analyzing samples, and documenting results to improve the efficiency and scalability of downstream processes like filtration and chromatography. Interns in this position gain hands-on experience with cutting-edge technologies and learn about regulatory requirements and industry standards. This role helps prepare students or recent graduates for a career in process development or biomanufacturing.

What types of projects and responsibilities can an internship downstream process development scientist expect to work on?

As an Internship Downstream Process Development Scientist, you can expect to be involved in hands-on laboratory work focusing on the purification and characterization of biopharmaceutical products. Typical responsibilities include preparing buffer solutions, operating chromatography and filtration systems, analyzing samples using various analytical techniques, and documenting experimental results. Interns often collaborate with experienced scientists and engineers, contributing to process optimization and troubleshooting. The role provides valuable exposure to industry-standard procedures and the opportunity to develop technical skills in a team-oriented environment.

What are the key skills and qualifications needed to thrive as an internship downstream process development scientist, and why are they important?

To thrive as an Internship Downstream Process Development Scientist, you need foundational knowledge in biochemistry, molecular biology, or chemical engineering, often supported by ongoing or recent enrollment in a relevant degree program. Familiarity with laboratory techniques such as chromatography, filtration, and analytical instruments, as well as experience with lab management software, is typically expected. Attention to detail, problem-solving abilities, and effective teamwork are standout soft skills in this role. These skills and qualifications are crucial for conducting reliable experiments, analyzing data, and contributing to the optimization of bioprocesses in a collaborative research environment.

What are the most commonly searched types of Downstream Process Development Scientist jobs in Madison, WI?

The most popular types of Downstream Process Development Scientist jobs in Madison, WI are:

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Internship Downstream Process Development Scientist jobs near you
Infographic showing various Internship Downstream Process Development Scientist job openings in Madison, WI as of July 2026, with employment types broken down into 1% As Needed, 80% Full Time, 14% Part Time, and 5% Contract. Highlights an 91% Physical, 2% Hybrid, and 7% Remote job distribution, with an average salary of $81,033 per year, or $39 per hour.

Senior Scientist II, Discovery Analytical Chemistry

Arrowhead Pharmaceuticals

Madison, WI • On-site

$92K - $126K/yr

Full-time

Re-posted 2 days ago

Job description

Arrowhead Pharmaceuticals, Inc. (Nasdaq ARWR) is a commercial stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Arrowhead's RNAi-based therapeutics leverage this natural pathway of gene silencing.

Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, typically characterized by the overproduction of one or more proteins that are involved with disease. The depth and versatility of our RNAi technologies enables us to potentially address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise addressable by small molecules and biologics. Arrowhead is leading the field in bringing the promise of RNAi to address diseases outside of the liver, and our clinical pipeline includes disease targets in the liver and lung with a promising pipeline of preclinical candidates.

Arrowhead's corporate headquarters is in Pasadena, CA with research and development teams in Madison, WI & San Diego, CA, and a state of the art manufacturing facility in Verona, WI. Our employees are nimble, science-driven innovators who are collaborating to bring new therapies to patients in need.

The Position

Arrowhead is seeking a highly motivated and experienced Senior Scientist on Analytical Chemistry to lead analytical method development, characterization, and testing activities supporting pharmaceutical development programs. This role will be responsible for developing and qualifying analytical methods, overseeing analytical activities performed at contract development and manufacturing organizations (CDMOs), and authoring analytical sections of regulatory submissions. The successful candidate will serve as a technical expert in Antibody oligo conjugate (AOC) drug characterization and will collaborate closely with Process Development, Manufacturing, Quality, Regulatory Affairs, and external partners.

Responsibilities

  • Design, develop, optimize, qualify, and transfer analytical methods to support development and manufacturing activities.
  • Lead analytical characterization studies for drug substances, intermediates, and related materials.
  • Develop and execute analytical strategies to assess product identity, purity, potency, impurities, and stability.
  • Interpret analytical data, investigate trends, and provide scientific recommendations to project teams.
  • Support method lifecycle management, troubleshooting, and continuous improvement activities.
  • Provide scientific and technical oversight of analytical development, testing, method qualification, and transfer activities conducted at CDMOs.
  • Review protocols, reports, deviations, investigations, and technical documents generated by external partners.
  • Monitor project timelines, deliverables, and analytical performance to ensure project objectives are achieved.
  • Serve as the primary analytical subject matter expert during interactions with CDMOs and contract testing laboratories.
  • Collaborate with Process Development, Manufacturing, Quality Control, Quality Assurance, Regulatory Affairs, and CMC teams to support program milestones.
  • Contribute to analytical control strategy development and product specification setting.
  • Present analytical findings and recommendations to internal teams and management.
  • Author and review analytical sections of regulatory submissions, including INDs, IMPDs, CTAs, BLAs, and other global regulatory filings.
  • Support responses to regulatory agency questions and inspections.
  • Ensure analytical activities comply with applicable GMP, ICH, FDA, EMA, and other regulatory requirements.
  • Participate in quality investigations, change controls, risk assessments, and CAPA activities as needed.

Requirements

  • PhD in analytical chemistry or close related fields with 5+ years pharmaceutical relevant industry experience; or M.S. with 8+ years of relevant industry experience; or B.S. with 10+ years of relevant industry experience.
  • Extensive knowledge of Oligo, mAb, ADC or AOC-related analytical techniques and applications.
  • Demonstrated expertise with chromatographic methods, including HPLC, UHPLC, and related analytical platforms.
  • Experience with GMP-regulated analytical development and testing environments.
  • Strong understanding of method transfer, validation, and lifecycle management principles.
  • Experience authoring analytical CMC documentation for regulatory submissions.
  • Strong scientific problem-solving and troubleshooting skills.
  • Excellent technical writing and communication abilities.
  • Ability to manage multiple projects in a fast-paced environment.
  • Strong organizational skills and attention to detail.
  • Effective collaborator with demonstrated ability to influence cross-functional teams and external partners.

Preferred

  • Hands-on Experience with Size Exclusion Chromatography coupled with Multi-Angle Light Scattering (SEC-MALS) is preferred but not necessary.
  • Experience supporting biologics, oligonucleotides, ADC, AOC or other complex modalities.
  • Prior experience managing external laboratories and CDMOs.
  • Familiarity with ICH guidelines and global regulatory expectations.
Wisconsin pay range
$130,000—$150,000 USD

Arrowhead provides competitive salaries and an excellent benefit package.

Candidates must have current, valid authorization to work in the country where this role is located.

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