Internship Bioinformatics Software Engineer Jobs in Memphis, TN

Job Summary:
St. Jude Children's Research Hospital is focused on advancing research in cancer immunology and infectious disease. They are seeking a Bioinformatics Research Scientist to develop and maintain computational pipelines for high-throughput immune repertoire sequencing and antibody discovery, collaborating closely with experimental scientists and data science teams.
Responsibilities:
• Independently perform basic and advanced level statistical analysis, algorithm implementation, programming from a variety of biotechnology platforms, and oversee quality check.
• Design and prepare materials and courses for training on various bioinformatics software and databases, computing, data mining, and analysis.
• Act as a liaison between end-users, software developers, system designers, and different departments.
• Establish protocols or best practices for common research tasks and SOP, evaluate products and solutions to make recommendations, and integrate solutions.
• Lead the development, implementation, installation, and maintenance of databases; coordinate data collection, database implementation, and usage and any hardware and software related to database collection.
• Develop programs to assist in the analysis of data within the databases.
• Assist in planning, coordinating, and organizing projects across departments and delegate tasks based on priority, expertise, and capacity.
• Perform other duties as assigned to meet the goals and objectives of the department and institution.
• Maintains regular and predictable attendance.
• Develop and maintain bioinformatics pipelines for TCR and BCR repertoire sequencing.
• Perform and oversee data QC, statistical analysis, and interpret repertoire datasets.
• Integrate immune repertoire data with clinical metadata and other multi-omics datasets.
• Document and maintain workflows and databases to ensure reproducibility, scalability, and long-term data and code reuse.
• Support infectious disease and host–microbe interaction studies, with emphasis on B cell responses and antibody discovery.
• Support immuno-oncology projects, including analysis of tumor-infiltrating lymphocytes and integration with tumor genomic and clinical data.
• Collaborate with investigators and serve as a technical liaison between wet-lab, clinical, and computational teams.
• Contribute to continuous improvement and expansion of TIRTL analytical capabilities.
Qualifications:
Required:
• Bachelor's degree in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry) or related field.
• Minimum Requirement: Bachelor's degree with 6+ years of relevant post-degree work in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry).
• Experience Exception: Master's degree with 4+ years of relevant post-degree experience (OR) PhD with no experience.
• Experience in at least one programming or scripting language and at least one statistical package, with R preferred.
• Significant experience in at least one programming or scripting language and at least one statistical package, with python/R preferred.
• Strong experience with high-throughput sequencing data analysis.
• Experience with Linux, hpc environments, version control and workflow systems.
• Independently perform basic and advanced level statistical analysis, algorithm implementation, programming from a variety of biotechnology platforms, and oversee quality check.
• Design and prepare materials and courses for training on various bioinformatics software and databases, computing, data mining, and analysis.
• Act as a liaison between end-users, software developers, system designers, and different departments.
• Establish protocols or best practices for common research tasks and SOP, evaluate products and solutions to make recommendations, and integrate solutions.
• Lead the development, implementation, installation, and maintenance of databases; coordinate data collection, database implementation, and usage and any hardware and software related to database collection.
• Develop programs to assist in the analysis of data within the databases.
• Assist in planning, coordinating, and organizing projects across departments and delegate tasks based on priority, expertise, and capacity.
• Perform other duties as assigned to meet the goals and objectives of the department and institution.
• Maintains regular and predictable attendance.
• Develop and maintain bioinformatics pipelines for TCR and BCR repertoire sequencing.
• Perform and oversee data QC, statistical analysis, and interpret repertoire datasets.
• Integrate immune repertoire data with clinical metadata and other multi-omics datasets.
• Document and maintain workflows and databases to ensure reproducibility, scalability, and long-term data and code reuse.
• Support infectious disease and host–microbe interaction studies, with emphasis on B cell responses and antibody discovery.
• Support immuno-oncology projects, including analysis of tumor-infiltrating lymphocytes and integration with tumor genomic and clinical data.
• Collaborate with investigators and serve as a technical liaison between wet-lab, clinical, and computational teams.
• Contribute to continuous improvement and expansion of TIRTL analytical capabilities.
Preferred:
• Experience with immune repertoire analysis (BCR and/or TCR).
• Familiarity with tools and methods for BCR clonotyping, somatic hypermutation analysis, lineage reconstruction, or antigen-driven selection.
• Background in cancer immunology, infectious disease, or antibody discovery.
• Master's degree or PhD preferred.
Company:
St. Founded in 1962, the company is headquartered in Memphis, USA, with a team of 5001-10000 employees. The company is currently Late Stage.