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Infusion Nurse Jobs in Rochester, MN (NOW HIRING)

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Infusion Nurse information

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How much do infusion nurse jobs pay per hour?

As of Aug 12, 2026, the average hourly pay for infusion nurse in Rochester, MN is $41.93, according to ZipRecruiter salary data. Most workers in this role earn between $36.15 and $47.88 per hour, depending on experience, location, and employer.

What are some common challenges faced by infusion nurses during patient care, and how are they typically addressed?

Infusion nurses often encounter challenges such as managing complicated intravenous access, handling adverse reactions to medications, and coordinating care for patients with chronic or complex conditions. To address these, they rely on thorough patient assessment, ongoing monitoring, and strong communication skills with both patients and the healthcare team. Additionally, infusion nurses must stay updated on the latest protocols and maintain meticulous documentation to ensure patient safety and effective treatment.

What is an infusion nurse?

An infusion nurse is a registered nurse who specializes in administering medications and fluids through intravenous (IV) lines, central lines, or venous access ports. They are skilled in starting and maintaining IVs, monitoring patients for reactions, and ensuring the safe delivery of treatments such as antibiotics, chemotherapy, or hydration therapy. Infusion nurses work in hospitals, outpatient clinics, and sometimes provide care in patients’ homes, always prioritizing patient safety and comfort during infusion procedures.

What is an infusion nurse?

An infusion nurse is a highly educated healthcare professional who has completed all the requirements to become a registered nurse (RN) or advanced practice nurse (APN). This training includes classroom and clinical learning, with specialized education and training in infusion services. Infusion services include any intravenous administration of blood or medication. As an infusion nurse, you help patients understand what to expect from the infusion treatment they are undergoing, check the drug or blood that you administer, verify it matches the orders, double check the identity of the patient, and deliver the infusion as painlessly as possible. You must be committed to sanitation and safety protocols to ensure the well-being of your patients.

What is the difference between Infusion Nurse vs Oncology Nurse?

AspectInfusion NurseOncology Nurse
CertificationsRN license, IV therapy certificationRN license, Oncology certification (OCN)
Work EnvironmentHospitals, clinics, home careHospitals, cancer centers, clinics
Job FocusAdministering IV medications, infusionsCancer patient care, chemotherapy administration

Infusion nurses primarily focus on administering IV therapies and infusions across various healthcare settings, while oncology nurses specialize in caring for cancer patients, often administering chemotherapy. Both roles require RN licensure and involve patient education, but infusion nurses emphasize IV skills, whereas oncology nurses focus on cancer treatment and symptom management.

What are the key skills and qualifications needed to thrive as an infusion nurse, and why are they important?

To thrive as an Infusion Nurse, you need a solid background in intravenous therapy, patient assessment, and medication administration, typically supported by an active RN license and specialized infusion certification. Familiarity with infusion pumps, electronic health records (EHRs), and safety protocols is essential for daily tasks. Strong communication, attention to detail, and the ability to reassure and educate patients are critical soft skills. These skills ensure safe, accurate delivery of therapies and foster trust and comfort for patients undergoing complex treatments.
What are the most commonly searched types of Infusion Nurse jobs in Rochester, MN? The most popular types of Infusion Nurse jobs in Rochester, MN are:
What are popular job titles related to Infusion Nurse jobs in Rochester, MN? For Infusion Nurse jobs in Rochester, MN, the most frequently searched job titles are:
What job categories do people searching Infusion Nurse jobs in Rochester, MN look for? The top searched job categories for Infusion Nurse jobs in Rochester, MN are:
What cities near Rochester, MN are hiring for Infusion Nurse jobs? Cities near Rochester, MN with the most Infusion Nurse job openings:
Infographic showing various Infusion Nurse job openings in Rochester, MN as of August 2026, with employment types broken down into 3% As Needed, 58% Full Time, 21% Part Time, and 18% Contract. Highlights an 97% Physical, and 3% Remote job distribution, with an average salary of $87,218 per year, or $41.9 per hour.

Registered Nurse - Oncology Chemotherapy Treatment Unit - Up to $15,000 Sign-On Bonus - RN

Mayo Clinic

Rochester, MN • On-site

Full-time

Medical, Dental, Vision, Retirement

Posted 12 days ago


Mayo Clinic rating

7.8

Company rating: 7.8 out of 10

Based on 697 frontline employees who took The Breakroom Quiz

130th of 887 rated healthcare providers


Job description


Mayo Clinic in Rochester is offering a generous starting bonus of up to $15,000 for joining our Chemotherapy unit. Starting bonus will be discussed during the hiring process.
As a Chemotherapy Infusion RN, you'll do more than deliver treatment. You'll make a lasting impact during some of the most critical moments in a patient's life.
If you've been looking for a role where your work truly matters, this is one of those places.
Why this team feels different
You'll join a team where you are supported, valued, and truly part of something. Leaders are approachable, and teammates show up for one another, because no one does this work alone.
Here, you're encouraged to grow, speak up, and bring your full self to the team.
The work you'll do
In our 53-chair outpatient oncology treatment unit (Gonda 10E), you will:
  • Administer chemotherapy, immunotherapy, and advanced cancer therapies
  • Support patients through education, therapeutic communication, and emotional care
  • Collaborate with a multidisciplinary team on innovative treatments and research

You'll work with ports, PICC lines, and IV placement while building meaningful relationships with patients throughout their care.
It's fast-paced, complex, and deeply meaningful work.
A place to grow
This team supports you in practicing at the top of your scope while continuing to build your expertise.
You'll have opportunities to precept, develop leadership skills, and grow your confidence and autonomy in daily practice.
You may be a great fit if you:
  • Want work that feels purposeful, not routine
  • Value being part of a supportive, team-oriented environment
  • Take pride in being both highly skilled and deeply compassionate

Position Details
The primary role of the RN in this position is administration of chemotherapeutic agents and patient education in the outpatient setting.
Watch what it's like to be a Chemotherapy Infusion RN at Mayo Clinic
Orientation and Growth
We are committed to helping you feel supported, prepared, and confident as you build your oncology nursing practice.
Your orientation includes:
  • 12+ hours of structured chemotherapy education
  • 12 hours of cancer core knowledge
  • Three months of guided, hands-on learning

You'll work side-by-side with a preceptor to build IV skills, strengthen critical thinking, and grow into the role step by step.
As cancer care continues to evolve, we prepare our nurses not only for today's patients, but for the therapies shaping the future of oncology care.
It's also an exciting time to join our team, with a 15-chair expansion planned for early 2027.
The registered nurse (RN) is accountable for:
  • Coordination of nursing care, including direct patient care, patient/family education and transitions of care.
  • Supporting professional nursing practice across practice settings and across the continuum of care to meet the needs of the patient and family.
  • Functioning within the Mayo Clinic Nursing Professional Practice Model, which includes accountability for planning, implementing, evaluating and communicating all phases of nursing care for assigned patients. The ANA Nursing: Scope and Standards of Practice provide a basis for the practice of the RN.
  • Providing leadership through activities such as preceptor role, informal and formal leadership roles, and quality improvement efforts.
  • Delegating patient care according to skill level, experience, patient acuity, fiscal accountability and availability of resources.
  • Possessing excellent communication skills; is skillful in mentoring and teaching; and may participate on committees or projects.
  • A subset of employees may be required to drive their personal vehicle as a part of the responsibility of their role.

For New Graduate Nurses: Please apply through the Nurse Residency Program posting, which is specifically designed to support New Graduate RNs. Visit the Nurse Residency webpage for program details including current and upcoming application windows. Within the Nurse Residency application process, you may indicate work units and specialties of interest. If selected to move forward, you will meet with a Nursing Placement Coordinator who will help you explore Mayo Clinic opportunities that are best aligned with your current and future professional goals. Together, we'll identify a work area that provides an excellent foundation for your nursing career.
The registered nurse (RN) is accountable for the coordination of nursing care, including direct patient care, patient/family education and transitions of care. The RN supports professional nursing practice across practice settings and across the continuum of care to meet the needs of the patient and family. The RN will function within the Mayo Clinic Nursing Professional Practice Model, which includes accountability for planning, implementing, evaluating and communicating all phases of nursing care for assigned patients. The ANA Nursing: Scope and Standards of Practice provide a basis for the practice of the RN. The RN provides leadership through activities such as preceptor role, informal and formal leadership roles, and quality improvement efforts. The RN delegates patient care according to skill level, experience, patient acuity, fiscal accountability and availability of resources. The RN possesses excellent communication skills; is skillful in mentoring and teaching; and may participate on committees or projects. A subset of employees may be required to drive their personal vehicle as a part of the responsibility of their role.
This role is eligible for TN sponsorship. Successful sponsorship will require state licensure and completion of the VisaScreen or equivalent certification.
Qualifications
Graduate of a nursing program, as recognized by the Accreditation Commission for Education in Nursing (ACEN), Commission on Collegiate Nursing Education (CCNE), National League for Nursing Commission for Nursing Education Accreditation (NLN CNEA). One year of RN experience required.
All entry-level associate degree registered nurses with a RN start date of April 1, 2020 and after must provide documented evidence of program completion of the baccalaureate degree in nursing from an accredited nursing program within five years from the last day of the month of the RN start date.
All entry-level associate degree registered nurses with a RN start date prior to April 1, 2020 must provide documented evidence of program completion of the baccalaureate degree in nursing from an accredited nursing program as stipulated by the degree requirement program in place at time of hire.
Additional Qualifications:
Excellent communication skills (verbal and written). Experience working in a team environment. Computer skills required, prior experience with electronic medical record systems preferred. Ability to adapt to unpredictable situations within the work setting. Demonstrated leadership, effective communicator, and excellent critical thinking skills.
Internal applicants are required to attach their three most recent performance appraisals.
License and Certification (Must obtain prior to start date):
Current RN license by applicable state requirements.
BLS (Basic Life Support) must be valid for 90 days post start date; acceptable certifications include: American Heart Association (AHA)/ Heartcode® BLS, Military Training Network, Red Cross (CPR/AED for Professional Rescuers and Health Care Providers).
Additional state licensure(s) and/or specialty certification/training as required by the work area.
About Us
Why Mayo Clinic
Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans - to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.
Benefits Highlights
  • Medical: Multiple plan options.
  • Dental: Delta Dental or reimbursement account for flexible coverage.
  • Vision: Affordable plan with national network.
  • Pre-Tax Savings: HSA and FSAs for eligible expenses.
  • Retirement: Competitive retirement package to secure your future.

About the Team
Just as our reputation has spread beyond our Minnesota roots, so have our locations. Today, our employees are located at our three major campuses in Phoenix/Scottsdale, Arizona, Jacksonville, Florida, Rochester, Minnesota, and at Mayo Clinic Health System campuses throughout Midwestern communities, and at our international locations. Each Mayo Clinic location is a special place where our employees thrive in both their work and personal lives. Learn more about what each unique Mayo Clinic campus has to offer, and where your best fit is.
Equal Opportunity
All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the "EOE is the Law". Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.

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About Mayo Clinic

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Mayo Clinic is the largest integrated, not-for-profit medical group practice in the world. We're building the future, one where the best possible care is available to everyone — and more people can heal at home. Our relentless research turns into earlier diagnoses and new cures. That's how we inspire hope in those who need it most. At Mayo Clinic, experts work together to solve the most challenging unmet needs of patients. Our history of innovation dates back almost 150 years, when brothers Will and Charlie Mayo pioneered an integrated, team-based approach to medicine. Today, that trailblazing spirit drives innovations like Mayo Clinic Platform — which powers new technologies to change how care is delivered to all.

Industry

Hospitals

Company size

10,000+ Employees

Headquarters location

Rochester, MN, US

Year founded

1919