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Independent Contractor Statistical Programmer Jobs

IQVIA

Principal Statistical Programmer, PKPD

Durham, NC

$98.20K - $273.20K/yr

PK parameter pooling Experience * 8+ years of statistical programming experience in the ... Ability to work independently while managing multiple priorities. * Detailoriented with a strong ...

IQVIA

Principal Statistical Programmer, PKPD

Durham, NC

$98.20K - $273.20K/yr

PK parameter pooling Experience * 8+ years of statistical programming experience in the ... Ability to work independently while managing multiple priorities. * Detailoriented with a strong ...

Exelixis

Statistical Programming Manager

Alameda, CA

Uses statistical software (SAS, R, etc) and/or data visualization tools (Tableau) to create and ... Independently verifies other programmer's results. Adheres to FDA regulations regarding training ...

Exelixis

Statistical Programming Manager

Alameda, CA

Uses statistical software (SAS, R, etc) and/or data visualization tools (Tableau) to create and ... Independently verifies other programmer's results. * Adheres to FDA regulations regarding training ...

Exelixis

Statistical Programming Manager

Alameda, CA · On-site

... Independently verifies other programmer's results. • Adheres to FDA regulations regarding ... statistical programming with clinical data and SAS. • Strong SAS programming skills required ...

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As of May 31, 2026, the average yearly pay for independent contractor statistical programmer in the United States is $147,292.00, according to ZipRecruiter salary data. Most workers in this role earn between $125,000.00 and $160,000.00 per year, depending on experience, location, and employer.
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Infographic showing various Independent Contractor Statistical Programmer job openings in the United States as of May 2026, with employment types broken down into 30% Full Time, and 70% Part Time. Highlights an 80% Physical, 1% Hybrid, and 19% Remote job distribution, with an average salary of $147,292 per year, or $70.8 per hour.

Senior Manager, Statistical Programming

Kardigan

Princeton, NJ • On-site

Full-time

Posted 4 days ago

Job description

About Us
Kardigan is a heart health company working to make cardiovascular disease preventable, curable and no longer the leading cause of death in the world.
It is Kardigan's mission to develop multiple targeted treatments in parallel that bring people with cardiovascular diseases to the cures they deserve.
Led by Tassos Gianakakos, Jay Edelberg, M.D., Ph.D., and Bob McDowell, Ph.D., Kardigan's co-founders have reunited after leading MyoKardia to discover and develop mavacamten, the first cardiac myosin inhibitor, resulting in an acquisition by Bristol Myers Squibb in 2020.
We have a cutting-edge discovery and translational research platform, a pipeline of late-stage candidates, and an industry-leading team that is driven to improve the lives of patients.
At Kardigan, we are motivated by our values which guide how we work, interact, and achieve our goals. Driven by patients and their families, we are deeply committed to improving the lives of patients and prioritizing their needs above all else. We believe in being authentic-leading with truth to bring out the best in others by creating an environment where every person knows they will be fully accepted. With an eagerness to learn, we encourage the highest levels of curiosity and are open to changing our minds. We are committed to winning as a team with urgency, excellence, and intention, and support each other no matter what role we play or where we sit. Lastly, we strive to enable the impossible because patients are counting on us. We are not afraid to take risks to unlock innovation and advance scientific discoveries.
These values are the foundation of our work, empowering us to make a real difference, every day.
Position Title: Senior Manager, Statistical Programming
Department: Clinical Data Sciences & Analytics
Reports To: Head of Statistical Programming
Location: South San Francisco, CA or Princeton, NJ - On-site 4 days per week (Mon to Thurs)
Job Overview:
The Senior Manager of Statistical Programming will be responsible for leading Statistical Programming activities. It involves hands-on implementation of statistical analyses using SAS/R, as well as performing quality reviews of deliverables, both for in-house analyses and outsourced programming tasks.
This position serves as a critical bridge between Biostatistics and Clinical Data Management (CDM), ensuring the development of CRFs and the delivery of high-quality clinical data. Additionally, this position will play an important role in helping establish SOPs and programming standards and also build our SCE platform.
ESSENTIAL DUTIES AND RESPONSIBILITIES
Key Project Responsibilities:
  • Provides programming leadership and oversee study to compound-level programming deliverable in collaboration with the Stats lead and cross-functional teams.
  • Serve as the lead programmer to reviews SAP, Data Presentation Plan, Table Shell to align with project objectives and ensures clarity and completeness of programming assumptions and requirements.
  • Lead programming team to produce and/or validate SDTM, ADaM and TLF, for CSR and regulatory requests, publication needs, and ad-hoc analyses.
  • Manage CROs and contractors, ensuring compliance, quality of deliverables, timelines, and budget adherence.
  • Collaborate with biostatisticians and clinical development colleagues to develop/review TLF shells, SDTM, and ADaM specifications.
  • Work closely with Data Management and Biostatistics teams to ensure the accuracy of final databases, analyses, and reports.
  • Develop global tools, such as macros or graphical user interface applications, to enhance the efficiency and capacity of the Statistical Programming team.
  • Develops robust program to create define.xml, Leads the NDA eSubmission package preparation.
  • Assist Biometric in building the statistical computing environment (SCE) platform, including designing folder structure and managing access control.

Initiative Responsibilities:
  • Under guidance from Head of Statistical Programming and Compound PL, implement innovative strategies and technologies to enhance programming processes.
  • Working with manager, establish Statistical Programming standard and deploy programming strategies, specifications and programmed analysis.
  • Proactively plan, implement, and identify issues/risks and provide remediation strategies to improve programming capability.

Qualifications and Preferred Skills
Education:
  • Master's degree in Statistics/Biostatistics, Mathematics, Computer Science, or a related field.

Experience and Skill Set:
  • Minimum of 6 years statistical programming experience in the pharmaceutical, biotech or CRO clinical trial environment.
  • Advanced SAS programming skills. Extensive Hands-on experience with SDTM, ADaM, TLF programming
  • Proficient knowledge in the implementation of CDISC standards (SDTM, ADaM) and regulatory submission requirements.
  • Good knowledge of drug development process, study design, statistical methodology, regulatory guidance, statistical concepts, and medical terminology.
  • Broad expertise in statistical programming and in developing computing strategies.
  • In-depth understanding of CDISC standards including SDTM and ADaM models and extensive experience of their implementation in clinical trials.
  • Demonstrated proficiency in using SAS/R to produce analysis datasets and TFLs.
  • Knowledge of data validation, define.xml generation using Pinnacle 21.
  • Results orientated with proven problem-solving skills and a strong interest in ongoing learning.
  • Excellent communication and collaboration skills, with the ability to work closely with cross-functional teams
  • Experience managing outsourced programming activities and overseeing deliverables from CROs and contractors.
  • Adaptable and thrives in a fast-paced, startup environment while managing multiple priorities effectively.
  • Experience with regulatory audits and inspections and IR (e.g., FDA, PMDA, NMPA, EMA) is a strong advantage.

Exact Compensation may vary based on skills, experience and location.
Pay range
$172,000-$234,000 USD

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