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Independent Contractor Principal Clinical Scientist Jobs

Principal Clinical Scientist . This role is responsible for clinical trial strategies within the US and EU regions for Danaher Diagnostics. This role will specifically support Beckman Coulter ...

Principal Clinical Scientist . This role is responsible for clinical trial strategies within the US and EU regions for Danaher Diagnostics. This role will specifically support Beckman Coulter ...

Principal Clinical Scientist . This role is responsible for clinical trial strategies within the US and EU regions for Danaher Diagnostics. This role will specifically support Beckman Coulter ...

Principal Clinical Scientist . This role is responsible for clinical trial strategies within the US and EU regions for Danaher Diagnostics. This role will specifically support Beckman Coulter ...

Principal Clinical Scientist . This role is responsible for clinical trial strategies within the US and EU regions for Danaher Diagnostics. This role will specifically support Beckman Coulter ...

Principal Clinical Scientist . This role is responsible for clinical trial strategies within the US and EU regions for Danaher Diagnostics. This role will specifically support Beckman Coulter ...

Principal Clinical Scientist . This role is responsible for clinical trial strategies within the US and EU regions for Danaher Diagnostics. This role will specifically support Beckman Coulter ...

Principal Clinical Scientist . This role is responsible for clinical trial strategies within the US and EU regions for Danaher Diagnostics. This role will specifically support Beckman Coulter ...

Principal Clinical Scientist

Chaska, MN · On-site

$120K - $165K/yr

Principal Clinical Scientist . This role is responsible for clinical trial strategies within the US and EU regions for Danaher Diagnostics. This role will specifically support Beckman Coulter ...

Principal Clinical Scientist . This role is responsible for clinical trial strategies within the US and EU regions for Danaher Diagnostics. This role will specifically support Beckman Coulter ...

Principal Clinical Scientist . This role is responsible for clinical trial strategies within the US and EU regions for Danaher Diagnostics. This role will specifically support Beckman Coulter ...

Principal Clinical Scientist . This role is responsible for clinical trial strategies within the US and EU regions for Danaher Diagnostics. This role will specifically support Beckman Coulter ...

Principal Clinical Scientist . This role is responsible for clinical trial strategies within the US and EU regions for Danaher Diagnostics. This role will specifically support Beckman Coulter ...

Principal Clinical Scientist . This role is responsible for clinical trial strategies within the US and EU regions for Danaher Diagnostics. This role will specifically support Beckman Coulter ...

Principal Clinical Scientist . This role is responsible for clinical trial strategies within the US and EU regions for Danaher Diagnostics. This role will specifically support Beckman Coulter ...

Principal Clinical Scientist . This role is responsible for clinical trial strategies within the US and EU regions for Danaher Diagnostics. This role will specifically support Beckman Coulter ...

Principal Clinical Scientist . This role is responsible for clinical trial strategies within the US and EU regions for Danaher Diagnostics. This role will specifically support Beckman Coulter ...

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Independent Contractor Principal Clinical Scientist information

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$68.5K

$144K

$190.5K

How much do independent contractor principal clinical scientist jobs pay per year?

As of Sep 6, 2026, the average yearly pay for independent contractor principal clinical scientist in the United States is $144,009.00, according to ZipRecruiter salary data. Most workers in this role earn between $117,500.00 and $169,000.00 per year, depending on experience, location, and employer.

What is an independent contractor principal clinical scientist?

An Independent Contractor Principal Clinical Scientist is a highly experienced professional in clinical research who works on a contract basis rather than as a full-time employee. They are responsible for designing, overseeing, and managing clinical trials to ensure that new drugs or medical devices are safe and effective for human use. As independent contractors, they often consult for multiple organizations, provide scientific expertise, and help ensure regulatory compliance. Their work includes protocol development, data interpretation, and leadership of study teams. This role requires strong scientific knowledge, project management skills, and the ability to work autonomously.

How does an independent contractor principal clinical scientist typically collaborate with cross-functional teams in clinical research projects?

As an Independent Contractor Principal Clinical Scientist, you will frequently collaborate with project managers, biostatisticians, regulatory affairs specialists, and medical writers. This role often involves leading scientific strategy discussions, providing guidance on clinical study design, and ensuring that project milestones are met according to regulatory and scientific standards. Effective communication and adaptability are key, as you may work remotely and coordinate across different time zones and organizational cultures. Your expertise also positions you as a mentor for junior scientists, contributing to the overall success and quality of clinical development programs.

What are the key skills and qualifications needed to thrive as an independent contractor principal clinical scientist, and why are they important?

To thrive as an Independent Contractor Principal Clinical Scientist, you need an advanced degree in life sciences or medicine, extensive experience in clinical research, and a thorough understanding of regulatory requirements. Familiarity with clinical trial management systems (CTMS), electronic data capture (EDC) tools, and certifications such as GCP (Good Clinical Practice) are typically required. Excellent leadership, critical thinking, and communication skills set top candidates apart, enabling them to manage cross-functional teams and complex studies. These competencies are vital to ensure the scientific integrity, regulatory compliance, and successful delivery of clinical research projects.
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Infographic showing various Independent Contractor Principal Clinical Scientist job openings in the United States as of August 2026, with employment types broken down into 55% Full Time, 18% Part Time, and 27% Contract. Highlights an 91% In-person, and 9% Remote job distribution, with an average salary of $144,009 per year, or $69.2 per hour.

Senior / Principal Clinical Scientist, Clinical Development

Immunome, Inc.

Bothell, WA • On-site

Full-time

Re-posted 21 days ago


Job description

Position Overview

We are seeking a highly motivated and experienced Clinical Scientist to join our team. The Senior / Principal Clinical Scientist, Clinical Development will play a critical role in the design, execution, and interpretation of multiple clinical trials for our oncology drug candidates. This individual will work closely with cross-functional teams, including clinical operations, regulatory affairs, and research and development, to ensure the successful progression of multiple clinical programs. 

Responsibilities

  • Oversee the execution of clinical trials and ensure scientific and regulatory rigor. 
  • Design and develop multiple clinical trial protocols, informed consent forms, and other study-related documents. 
  • Collaborate with principal investigators, key opinion leaders, and clinical trial sites to ensure robust study design and execution. Serve as Lead Clinical Scientist for multiple trials. 
  • Conduct activities related to data generation and validation, including CRF design and clinical data review/query resolution. 
  • Contribute to the preparation of clinical study reports, regulatory submissions, and publications. 
  • Review development of site and CRA training materials and presentation at SIV and Investigator meetings and support on Study committee (e.g., DMC) activities. 
  • Perform site-facing activities such as training and responding to clinical questions. 
  • Participate in the strategic development of clinical development plans and timelines. 
  • Present clinical trial data and findings to internal and external stakeholders, including scientific advisory boards and regulatory agencies. 
  • Mentor and develop junior team members with potential to manage direct reports. 

Qualifications

  • PhD, MD, PharmD, MS, or equivalent degree in life sciences. 
  • A minimum of 2 years of experience in clinical science, clinical research, or equivalent; clinical development experience is required, biopharmaceutical/biotechnology industry and oncology experience preferred. 
  • Strong leadership, project management, and communication skills. 
  • Travel may be required. 

Knowledge and Skills

  • Extensive experience in drug development process, study design, clinical operations. 
  • Extensive experience in clinical trial data analysis software and tools. 
  • Strong knowledge and skills to support program specific data review, trend identification, and data interpretation. 
  • Strong understanding of regulatory requirements and guidelines for clinical trials (e.g., GCP, ICH, FDA). 
  • Excellent analytical, organizational, and communication skills. 
  • Ability to work effectively in a fast-paced, collaborative environment. 
  • Strong problem-solving skills and attention to detail. 

WA State Range: Senior Clinical Scientist, Clinical Development - $145,823 - $182,019 

WA State Range: Principal Clinical Scientist, Clinical Development - $169,883 - $200,742