ZipRecruiter

Log In

2

Full Time Principal Clinical Scientist Jobs (NOW HIRING)

Danaher

Principal Clinical Scientist

Los Angeles, CA · On-site +1

Principal Clinical Scientist . This role is responsible for clinical trial strategies within the US and EU regions for Danaher Diagnostics. This role will specifically support Beckman Coulter ...

Danaher

Principal Clinical Scientist

Miami, FL · On-site +1

Principal Clinical Scientist . This role is responsible for clinical trial strategies within the US and EU regions for Danaher Diagnostics. This role will specifically support Beckman Coulter ...

Danaher

Principal Clinical Scientist

San Francisco, CA · On-site +1

Principal Clinical Scientist . This role is responsible for clinical trial strategies within the US and EU regions for Danaher Diagnostics. This role will specifically support Beckman Coulter ...

Danaher

Principal Clinical Scientist

Charlotte, NC · On-site +1

Principal Clinical Scientist . This role is responsible for clinical trial strategies within the US and EU regions for Danaher Diagnostics. This role will specifically support Beckman Coulter ...

Danaher

Principal Clinical Scientist

Tulsa, OK · On-site +1

Principal Clinical Scientist . This role is responsible for clinical trial strategies within the US and EU regions for Danaher Diagnostics. This role will specifically support Beckman Coulter ...

Danaher

Principal Clinical Scientist

Detroit, MI · On-site +1

Principal Clinical Scientist . This role is responsible for clinical trial strategies within the US and EU regions for Danaher Diagnostics. This role will specifically support Beckman Coulter ...

Danaher

Principal Clinical Scientist

Raleigh, NC · On-site +1

Principal Clinical Scientist . This role is responsible for clinical trial strategies within the US and EU regions for Danaher Diagnostics. This role will specifically support Beckman Coulter ...

Danaher

Principal Clinical Scientist

Atlanta, GA · On-site +1

Principal Clinical Scientist . This role is responsible for clinical trial strategies within the US and EU regions for Danaher Diagnostics. This role will specifically support Beckman Coulter ...

Danaher

Principal Clinical Scientist

Chaska, MN · On-site

$120K - $165K/yr

Principal Clinical Scientist . This role is responsible for clinical trial strategies within the US and EU regions for Danaher Diagnostics. This role will specifically support Beckman Coulter ...

Danaher

Principal Clinical Scientist

Cleveland, OH · On-site +1

Principal Clinical Scientist . This role is responsible for clinical trial strategies within the US and EU regions for Danaher Diagnostics. This role will specifically support Beckman Coulter ...

Danaher

Principal Clinical Scientist

Chaska, MN · On-site +1

Principal Clinical Scientist . This role is responsible for clinical trial strategies within the US and EU regions for Danaher Diagnostics. This role will specifically support Beckman Coulter ...

Danaher

Principal Clinical Scientist

Las Vegas, NV · On-site +1

Principal Clinical Scientist . This role is responsible for clinical trial strategies within the US and EU regions for Danaher Diagnostics. This role will specifically support Beckman Coulter ...

Danaher

Principal Clinical Scientist

Boston, MA · On-site +1

Principal Clinical Scientist . This role is responsible for clinical trial strategies within the US and EU regions for Danaher Diagnostics. This role will specifically support Beckman Coulter ...

Danaher

Principal Clinical Scientist

San Diego, CA · On-site +1

Principal Clinical Scientist . This role is responsible for clinical trial strategies within the US and EU regions for Danaher Diagnostics. This role will specifically support Beckman Coulter ...

Danaher

Principal Clinical Scientist

Denver, CO · On-site +1

Principal Clinical Scientist . This role is responsible for clinical trial strategies within the US and EU regions for Danaher Diagnostics. This role will specifically support Beckman Coulter ...

Danaher

Principal Clinical Scientist

Milwaukee, WI · On-site +1

Principal Clinical Scientist . This role is responsible for clinical trial strategies within the US and EU regions for Danaher Diagnostics. This role will specifically support Beckman Coulter ...

Danaher

Principal Clinical Scientist

Phoenix, AZ · On-site +1

Principal Clinical Scientist . This role is responsible for clinical trial strategies within the US and EU regions for Danaher Diagnostics. This role will specifically support Beckman Coulter ...

next page

Showing results 1-20

All Jobsfull time JobsScience JobsResearch JobsScientist JobsFull Time Principal Clinical Scientist Jobs

Full Time Principal Clinical Scientist information

See salary details

$68.5K

$144K

$190.5K

How much do full time principal clinical scientist jobs pay per year?

As of Sep 6, 2026, the average yearly pay for full time principal clinical scientist in the United States is $144,009.00, according to ZipRecruiter salary data. Most workers in this role earn between $117,500.00 and $169,000.00 per year, depending on experience, location, and employer.

What is a full time principal clinical scientist?

Full Time Principal Clinical Scientists are senior professionals who lead and oversee clinical research projects within healthcare or pharmaceutical organizations. They are responsible for designing, implementing, and managing clinical trials, ensuring regulatory compliance, and analyzing research data. Principal Clinical Scientists often serve as scientific experts, collaborating with cross-functional teams to advance clinical development programs. Their leadership plays a crucial role in bringing new medical treatments or technologies from concept to market. Typically, they hold advanced degrees and have substantial experience in clinical research.

What are the key skills and qualifications needed to thrive as a full time principal clinical scientist?

To thrive as a Full Time Principal Clinical Scientist, you need advanced scientific knowledge, a relevant postgraduate degree (such as a PhD or equivalent), and substantial experience in clinical research or laboratory science. Familiarity with clinical trial management systems, statistical software, and compliance with regulatory frameworks like GCP are typically required. Exceptional leadership, communication, and problem-solving skills distinguish top performers in this role. These skills and qualifications are essential for ensuring rigorous scientific standards, effective project management, and successful collaboration in complex clinical environments.

What are some common challenges faced by principal clinical scientists when leading multi-disciplinary clinical trials?

Principal Clinical Scientists often face the challenge of coordinating complex projects that involve cross-functional teams, including clinicians, statisticians, regulatory experts, and research coordinators. Balancing scientific rigor with operational efficiency, ensuring regulatory compliance, and managing tight timelines are frequent hurdles. Additionally, adapting study protocols in response to real-time data while maintaining high ethical and scientific standards requires strong leadership and communication skills. Successful Principal Clinical Scientists are adept at navigating these dynamics to drive clinical trials to completion.

What is the difference between Full Time Principal Clinical Scientist vs Clinical Research Scientist?

AspectFull Time Principal Clinical ScientistClinical Research Scientist
Required CredentialsAdvanced degree (PhD, MD, or equivalent), relevant certificationsBachelor's or Master's degree in life sciences or related field
Work EnvironmentPharmaceutical companies, biotech firms, clinical research organizationsResearch labs, clinical trial sites, academic institutions
Employer & Industry UsageUsed in industry settings focusing on clinical development and regulatory complianceCommon in academic, research, and early-phase clinical studies

The Full Time Principal Clinical Scientist typically holds advanced degrees and works in industry settings overseeing clinical trials and regulatory processes. In contrast, Clinical Research Scientists often have a bachelor's or master's degree and focus on conducting research and supporting clinical studies. Both roles are essential in the clinical research field but differ in seniority, scope, and work environment.

What cities are hiring for Full Time Principal Clinical Scientist jobs?

Cities with the most Full Time Principal Clinical Scientist job openings:

What are the most commonly searched types of Principal Clinical Scientist jobs?

The most popular types of Principal Clinical Scientist jobs are:

What states have the most Full Time Principal Clinical Scientist jobs?

States with the most job openings for Full Time Principal Clinical Scientist jobs include:

Full Time Principal Clinical Scientist jobs near you
Infographic showing various Full Time Principal Clinical Scientist job openings in the United States as of August 2026, with employment types broken down into 3% As Needed, 71% Full Time, 18% Part Time, and 8% Contract. Highlights an 95% Physical, 1% Hybrid, and 4% Remote job distribution, with an average salary of $144,009 per year, or $69.2 per hour.

Senior / Principal Clinical Scientist, Clinical Development

Immunome, Inc.

Bothell, WA • On-site

Full-time

Re-posted 21 days ago

Job description

Position Overview

We are seeking a highly motivated and experienced Clinical Scientist to join our team. The Senior / Principal Clinical Scientist, Clinical Development will play a critical role in the design, execution, and interpretation of multiple clinical trials for our oncology drug candidates. This individual will work closely with cross-functional teams, including clinical operations, regulatory affairs, and research and development, to ensure the successful progression of multiple clinical programs. 

Responsibilities

  • Oversee the execution of clinical trials and ensure scientific and regulatory rigor. 
  • Design and develop multiple clinical trial protocols, informed consent forms, and other study-related documents. 
  • Collaborate with principal investigators, key opinion leaders, and clinical trial sites to ensure robust study design and execution. Serve as Lead Clinical Scientist for multiple trials. 
  • Conduct activities related to data generation and validation, including CRF design and clinical data review/query resolution. 
  • Contribute to the preparation of clinical study reports, regulatory submissions, and publications. 
  • Review development of site and CRA training materials and presentation at SIV and Investigator meetings and support on Study committee (e.g., DMC) activities. 
  • Perform site-facing activities such as training and responding to clinical questions. 
  • Participate in the strategic development of clinical development plans and timelines. 
  • Present clinical trial data and findings to internal and external stakeholders, including scientific advisory boards and regulatory agencies. 
  • Mentor and develop junior team members with potential to manage direct reports. 

Qualifications

  • PhD, MD, PharmD, MS, or equivalent degree in life sciences. 
  • A minimum of 2 years of experience in clinical science, clinical research, or equivalent; clinical development experience is required, biopharmaceutical/biotechnology industry and oncology experience preferred. 
  • Strong leadership, project management, and communication skills. 
  • Travel may be required. 

Knowledge and Skills

  • Extensive experience in drug development process, study design, clinical operations. 
  • Extensive experience in clinical trial data analysis software and tools. 
  • Strong knowledge and skills to support program specific data review, trend identification, and data interpretation. 
  • Strong understanding of regulatory requirements and guidelines for clinical trials (e.g., GCP, ICH, FDA). 
  • Excellent analytical, organizational, and communication skills. 
  • Ability to work effectively in a fast-paced, collaborative environment. 
  • Strong problem-solving skills and attention to detail. 

WA State Range: Senior Clinical Scientist, Clinical Development - $145,823 - $182,019 

WA State Range: Principal Clinical Scientist, Clinical Development - $169,883 - $200,742 

Apply