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Illumina Bioinformatics Jobs (NOW HIRING)

Optimize and accelerate software executed on Illumina instruments * Closely interact with the bioinformatics team, instrument design team, test and quality teams * Collaborate in an agile environment ...

At Illumina, we are expanding access to genomic technology to realize health equity for billions of ... Bachelor's degree or higher in Computer Science, Engineering, Bioinformatics, or a related field ...

$129 - $194/hr

Or all of humanity?## At Illumina, we are expanding access to genomic technology to realize health ... Bachelor's degree or higher in Computer Science, Engineering, Bioinformatics, or a related field ...

Sr Software Engineer

San Diego, CA · On-site

$129 - $194/hr

At Illumina, we are expanding access to genomic technology to realize health equity for billions of ... Experience with NGS and Bioinformatics is a plus. * Additional Skills: Proven track record of ...

Posted Todayjob requisition id: 42673-JOB## At Illumina, we are expanding access to genomic ... bioinformatics -- sufficient to engage credibly with R&D and scientific customers.* Experience ...

New

Sr Software Engineer

San Diego, CA · On-site

$130K - $171K/yr

At Illumina, we are expanding access to genomic technology to realize health equity for billions of ... Experience with NGS and Bioinformatics is a plus. Additional Skills: * Proven track record of ...

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Illumina Bioinformatics information

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$59.5K

$94.5K

$149.5K

How much do illumina bioinformatics jobs pay per year?

As of Sep 4, 2026, the average yearly pay for illumina bioinformatics in the United States is $94,474.00, according to ZipRecruiter salary data. Most workers in this role earn between $67,500.00 and $129,500.00 per year, depending on experience, location, and employer.

What is Illumina bioinformatics?

Illumina bioinformatics refers to the computational analysis and interpretation of data generated by Illumina sequencing platforms. This field combines biology, computer science, and statistics to process large-scale genomic data, such as DNA or RNA sequences, and extract meaningful biological insights. Professionals working in Illumina bioinformatics use specialized software and pipelines to perform tasks like quality control, alignment, variant calling, and data visualization. Their work is essential for applications in genomics research, clinical diagnostics, and personalized medicine.

What are the key skills and qualifications needed to thrive as an Illumina bioinformatics specialist?

To thrive as an Illumina Bioinformatics Specialist, you need a strong background in molecular biology, genomics, and computational data analysis, usually backed by a degree in bioinformatics or a related field. Familiarity with next-generation sequencing (NGS) platforms, especially Illumina instruments, and proficiency in scripting languages like Python or R are crucial, along with experience using bioinformatics tools and databases. Excellent problem-solving, communication, and teamwork skills help in collaborating with researchers and troubleshooting complex datasets. These abilities are essential for ensuring accurate genomic data interpretation and supporting innovative research and clinical applications.

What are some common challenges faced by Illumina bioinformatics specialists and how can they be addressed?

Illumina Bioinformatics Specialists often encounter challenges such as managing large-scale sequencing data, ensuring data quality, and keeping up with rapidly evolving analysis tools and software. Collaborating closely with wet-lab scientists and IT teams is essential to streamline data processing and troubleshoot technical issues. Staying engaged with ongoing training and participating in interdisciplinary meetings can help specialists stay updated on best practices and emerging technologies, which is key for both effective problem-solving and professional growth.

What is the difference between Illumina Bioinformatics vs Bioinformatics Analyst?

AspectIllumina BioinformaticsBioinformatics Analyst
Required CredentialsBachelor's or Master's in Bioinformatics, Genetics, or related field; experience with sequencing dataBachelor's or Master's in Bioinformatics, Computer Science, or related; familiarity with data analysis tools
Work EnvironmentLaboratories, sequencing facilities, biotech companiesResearch institutions, biotech firms, healthcare settings
Industry UsagePrimarily in genomics, sequencing, and biotech companiesBroadly in healthcare, research, and biotech sectors

Illumina Bioinformatics specialists focus on analyzing sequencing data generated by Illumina platforms, often working within genomics and biotech companies. Bioinformatics Analysts have a broader scope, working across various data types and industries. While both roles require strong analytical skills and bioinformatics knowledge, Illumina Bioinformatics roles emphasize sequencing data analysis specific to Illumina technology.

More about Illumina Bioinformatics jobs

What cities are hiring for Illumina Bioinformatics jobs?

Cities with the most Illumina Bioinformatics job openings:

What states have the most Illumina Bioinformatics jobs?

States with the most job openings for Illumina Bioinformatics jobs include:

Infographic showing various Illumina Bioinformatics job openings in the United States as of August 2026, with employment types broken down into 83% Full Time, 14% Part Time, and 3% Contract. Highlights an 74% Physical, 4% Hybrid, and 22% Remote job distribution, with an average salary of $94,474 per year, or $45.4 per hour.

Staff Software Engineer

Illumina, Inc.

San Diego, CA • On-site

Full-time

Medical, Dental, Vision, Retirement, PTO

Posted 23 days ago


Illumina rating

8.3

Company rating: 8.3 out of 10

Based on 9 frontline employees who took The Breakroom Quiz

118th of 496 rated machine equipment manufacturers


Job description

What if the work you did every day could impact the lives of people you know? Or all of humanity?
At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients.
Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world changing projects, you will do more and become more than you ever thought possible.
What if the work you did everyday could impact the lives of people you know? Or all of humanity? At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients. Working at Illumina means being part of something bigger than yourself. Every person, in every role, can make a difference. Surrounded by extraordinary people, inspiring leaders, and world-changing projects, you will do more and become more than you ever thought possible.
We are searching for a software engineer who is ready to join us in this important mission.
Illumina's Primary Analysis team specializes in designing algorithms and developing software to detect genomic data from signals contained within images. Implementation challenges include managing parallel tasks, optimizing memory accesses, and improving the speed and accuracy of genomic base calling. We develop methods to address these challenges by focusing on high reliability, speed, and completeness of results. We are seeking an exceptional individual to join our team in developing analysis solutions for use by researchers and clinicians worldwide.
Responsibilities:
  • Define software architecture solutions for our high-performance signal processing pipelines
  • Design, develop, debug, and integrate C/C++ software on Linux for multi-threaded applications
  • Optimize and accelerate software executed on Illumina instruments
  • Closely interact with the bioinformatics team, instrument design team, test and quality teams
  • Collaborate in an agile environment to maintain high quality software against established processes
  • Maintain awareness of industry trends and evaluate applicability of new software and hardware technologies to platform development efforts
  • Provide technical leadership where needed

Requirements:
  • Extensive knowledge and experience with C/C++, Java or C#
  • Experience in multi-threading, and memory management techniques
  • Proficient with tools for software debugging and troubleshooting (GDB, etc.)
  • Proficient with tools for software performance analysis and optimization
  • Proficient with source control management repositories (such as GIT, SVN, etc.)
  • Extensive experience writing high quality unit tests against mock objects
  • Good understanding of object-oriented analysis and design
  • Strong problem-solving skills

Desired:
  • Extensive knowledge and experience in developing software for real-time systems
  • Experience with image processing algorithms and techniques
  • Experience with time-series analysis and interpretation of temporal data
  • Experience with Python and Python visualization libraries
  • Be customer-focused, team-oriented, and motivated, taking ownership of assigned tasks
  • Have proven ability to self-manage, as well as manage interdisciplinary relationships
  • Have proven verbal and written communication skills

Education & Experience:
  • BS/MS in Computer Science, EE, Bioinformatics, or related field
  • 8+ years of professional software development experience

#LI-HYBRID
The estimated base salary range for the Staff Software Engineer role based in the United States of America is: $155,600 - $233,400. Should the level or location of the role change during the hiring process, the applicable base pay range may be updated accordingly. The range reflects long-term growth in the role; therefore, most candidates are hired between the minimum and middle of the range. Placement depends on experience, skills, location, and internal equity. Additionally, all employees are eligible for one of our variable cash programs (bonus or commission) and eligible roles may receive equity as part of the compensation package. We offer a wide range of benefits as innovative as our work, including access to genomics sequencing, family planning, health/dental/vision, retirement benefits, and paid time off.
We are a company deeply rooted in belonging, promoting an inclusive environment where employees feel valued and empowered to contribute to our mission. Built on a strong foundation, Illumina has always prioritized openness, collaboration, and seeking alternative perspectives to propel innovation in genomics. We are proud to confirm a zero-net gap in pay, regardless of gender, ethnicity, or race. We also have several Employee Resource Groups (ERG) that deliver career development experiences, increase cultural awareness, and offer opportunities to engage in social responsibility. We are proud to be an equal opportunity employer committed to providing employment opportunity regardless of sex, race, creed, color, gender, religion, marital status, domestic partner status, age, national origin or ancestry, physical or mental disability, medical condition, sexual orientation, pregnancy, military or veteran status, citizenship status, and genetic information. Illumina conducts background checks on applicants for whom a conditional offer of employment has been made. Qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable local, state, and federal laws. Background check results may potentially result in the withdrawal of a conditional offer of employment. The background check process and any decisions made as a result shall be made in accordance with all applicable local, state, and federal laws. Illumina prohibits the use of generative artificial intelligence (AI) in the application and interview process. If you require accommodation to complete the application or interview process, please contact accommodations@illumina.com. To learn more, visit: https://www.dol.gov/ofccp/regs/compliance/posters/pdf/eeopost.pdf. The position will be posted until a final candidate is selected or the requisition has a sufficient number of qualified applicants.

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