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At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at jnj.com
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Job Function:
Discovery & Pre-Clinical/Clinical Development
Job Sub Function:
Translational Discovery & Development Biomarkers
Job Category:
Scientific/Technology
All Job Posting Locations:
Spring House, Pennsylvania, United States of America
Job Description:
About Innovative Medicine
Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.
Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.
Learn more at https://www.jnj.com/innovative-medicine
About Immunology
Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.
Our Immunology team leads in the development of transformational medicines for immunological disorders and illnesses. You can influence where medicine is going by restoring health to millions of people living with immune diseases.
Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.
We are searching for the best talent for a Director, Clinical Imaging-Translational Science- Immunology, to be in Spring House, PA or Cambridge, MA.
The Director, Clinical Imaging will provide strategic and scientific leadership for the development, validation, and delivery of imaging-derived endpoints to enable high-impact decision-making across the Immunology portfolio, with a primary focus on Gastrointestinal (GI) diseases. The role is US-based (Spring House, PA or Cambridge) and sits within the Translational Science organization, operating in a highly matrixed environment across Immunology Disease Area Strategy, Clinical Development, Data Sciences, Regulatory, and operational functions. This position is intentionally scoped and graded to ensure imaging and digital capabilities are positioned as strategic assets for Immunology, driving endpoint innovation for precision medicine from early to late phase. The Director will balance innovation, platform building, and technical delivery, ensuring that advanced measurement approaches are translated into fit-for-purpose, scalable solutions that support portfolio objectives.
Key Responsibilities:
Scientific & Strategic Technology Leadership

• Lead the GI-focused imaging measurement strategy across Immunology assets, spanning early through late-phase clinical development.
• Shape endpoint strategies integrating imaging measurements to support mechanistic understanding, proof-of-concept, and decision-enabling outcomes including regulatory.
• Partner with Disease Area Strategy and Translational Science leaders to ensure alignment with portfolio priorities and clinical development plans.
• Contribute to investment cases, governance discussions, and portfolio reviews, articulating value, readiness, and risk.

Clinical Trial Delivery & Execution

• Provide scientific oversight and accountability for imaging endpoints across early- and late-phase clinical trials.
• Ensure methods have an operationally delivery model to scale.
• Partner with clinical and operational partners across the organization, Data Sciences, and external vendors/CROs to ensure on-time, high-quality delivery.
• Support regulatory interactions related to imaging endpoints.

Innovation, AI & Capability Building

• Identify and advance next-generation imaging technologies with clear trajectories to GI pipeline impact from novel molecular methods through to AI-based structural endpoints.
• Lead the integration of AI-enabled analytics for imaging and digital endpoints, in close partnership with the Data Science organization.
• Co-develop AI-based solutions (e.g. automated image analysis, quantitative feature extraction, digital signal interpretation) to improve scalability, reproducibility, and decision-making in high impact areas.
• Build and sustain external collaborations with academia, technology partners, and pre-competitive consortia.
• Translate emerging methods into pragmatic clinical solutions balancing innovation with feasibility and timelines.

Matrix Leadership & Influence

• Partner closely with the Imaging and Digital Health team colleagues to drive innovation and delivery across disease areas.
• Operate effectively in a complex, global matrix environment and influence to guide strategy.
• Serve as a trusted scientific advisor to project teams, DAS leadership, and senior stakeholders.
• Communicate complex technical concepts with clarity and impact to diverse audiences.
• Mentor and develop scientists and matrix partners, contributing to a culture of scientific excellence and accountability.

Qualifications & Experience
Required

• PhD or MD, or equivalent advanced degree in a relevant scientific or clinical discipline.
• Minimum 10 years of experience in pharmaceutical or biotech R&D.
• Demonstrated experience applying imaging in interventional clinical trials.
• Proven ability to balance innovation with reliable execution in complex development environments.
• Exceptional written, verbal and presentation skills.
• Strong track record of working effectively in highly matrixed global organisations.

Preferred

• Experience in Gastrointestinal diseases, including Crohn's disease and ulcerative colitis.
• Experience working in close partnership with AI/ML teams to develop or deploy analytics for clinical trials.
• Familiarity with AI-enabled image analysis, digital biomarker pipelines, or quantitative imaging workflows.
• Exposure to regulatory interactions involving imaging endpoints.
• Experience managing external partnerships with technology vendors, CROs and academic collaborators.

Success in the First 12 Months

• Establish clear ownership and strategic direction for GI imaging endpoints aligned to GI Disease Area Strategy and clinical development teams.
• Establish an effective operating model with the Data Science organisation to deliver AI-enabled analytics for imaging and digital endpoints.
• Exhibit disciplined scientific and portfolio decision-making, including refinement or discontinuation of approaches where pipeline value is not compelling.
• Be recognised by project teams and senior stakeholders as a trusted scientific and strategic leader who balances innovation with delivery.

Why Johnson & Johnson
At Johnson & Johnson Innovative Medicine, we are redefining how clinical evidence is generated. This role offers the opportunity to shape how imaging, digital measurement, and AI-enabled analytics transform Immunology drug development, delivering tangible impact for patients while building future-facing scientific capabilities.
The anticipated base pay range for this position is $160,000 to $276,000
Employees and/or eligible dependents may be eligible to participate in the following Company sponsored employee benefit programs: medical, dental, vision, life insurance, short- and long-term disability, business accident insurance, and group legal insurance.
Employees may be eligible to participate in the Company's consolidated retirement plan (pension) and savings plan (401(k)).
This position is eligible to participate in the Company's long-term incentive program.
Employees are eligible for the following time off benefits:
- Vacation - up to 120 hours per calendar year
- Sick time - up to 40 hours per calendar year; for employees who reside in the State of Washington - up to 56 hours per calendar year
- Holiday pay, including Floating Holidays - up to 13 days per calendar year
- Work, Personal and Family Time - up to 40 hours per calendar year
Additional information can be found through the link below. For additional general information on company benefits, please go to: - https://www.careers.jnj.com/employee-benefits
Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.
Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants' needs. If you are an individual with a disability and would like to request an accommodation, external applicants please contact us via https://www.jnj.com/contact-us/careers . Internal employees contact AskGS to be directed to your accommodation resource.
#LI-Hybrid
Required Skills:
Preferred Skills:
Clinical Evaluations, Coaching, Critical Thinking, Drug Discovery Development, Entrepreneurship, Good Clinical Practice (GCP), Leadership, Medicines and Device Development and Regulation, Organizing, Regulatory Affairs Management, Relationship Building, Research Documents, Safety-Oriented, Scientific Research, Standard Scientific Processes and Procedures, Strategic Change, Study Management
The anticipated base pay range for this position is :
$164,000.00 - $282,900.00
Additional Description for Pay Transparency: