Home Infusion Nurses require strong clinical assessment skills, IV therapy expertise, and a valid RN license, often with additional certification in infusion nursing such as CRNI (Certified Registered Nurse Infusion). Proficiency with infusion pumps, electronic charting systems, and safe handling of medications is essential. Compassion, independence, and excellent communication skills help nurses excel in home settings where they work one-on-one with patients and coordinate with remote healthcare teams. These skills ensure safe, effective care delivery and foster trust with patients and families in a home environment.