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Histocompatibility Laboratory Director Jobs (NOW HIRING)

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Histocompatibility Laboratory Director information

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$45K

$126.1K

$186K

How much do histocompatibility laboratory director jobs pay per year?

As of Sep 13, 2026, the average yearly pay for histocompatibility laboratory director in the United States is $126,086.00, according to ZipRecruiter salary data. Most workers in this role earn between $106,000.00 and $138,500.00 per year, depending on experience, location, and employer.

What is a histocompatibility laboratory director?

A Histocompatibility Laboratory Director is a specialized professional who oversees labs that perform tissue typing and compatibility testing for organ, tissue, and bone marrow transplantation. They ensure accurate testing for human leukocyte antigens (HLA) to match donors and recipients, supervise laboratory staff, maintain quality control, and ensure compliance with regulatory standards. The director also interprets complex immunogenetic data, consults with physicians, and plays a critical role in transplant success and patient safety.

What are the key skills and qualifications needed to thrive as a histocompatibility laboratory director?

To thrive as a Histocompatibility Laboratory Director, you need advanced knowledge in immunogenetics, molecular diagnostics, and laboratory management, typically supported by an MD or PhD and board certification (such as from the American Board of Histocompatibility and Immunogenetics). Familiarity with HLA typing platforms, quality assurance systems, and regulatory compliance (e.g., CLIA, CAP) is essential. Strong leadership, communication, and problem-solving skills are crucial for supervising staff and collaborating with transplant teams. These competencies ensure the accuracy and reliability of compatibility testing, which is vital for successful organ transplantation and patient outcomes.

What are the main challenges a histocompatibility laboratory director faces in ensuring regulatory compliance and high-quality test results?

One of the primary challenges for a Histocompatibility Laboratory Director is keeping the laboratory in full compliance with evolving regulatory standards from organizations like CLIA and ASHI. This often involves updating protocols, overseeing staff training, and conducting internal audits to maintain accreditation. Additionally, Directors must manage quality assurance programs to ensure accurate and timely test results, as these are critical for patient outcomes in organ and stem cell transplantation. Balancing administrative responsibilities with scientific oversight, while fostering a collaborative team environment, is key to success in this role.

What is the difference between Histocompatibility Laboratory Director vs Histocompatibility Laboratory Supervisor?

AspectHistocompatibility Laboratory DirectorHistocompatibility Laboratory Supervisor
CredentialsTypically requires certification (e.g., ASHI), advanced degree, and extensive experienceUsually requires certification and relevant laboratory experience, but less advanced education
Work EnvironmentOversees entire laboratory operations, manages staff, and ensures complianceSupervises daily technical activities and laboratory staff
Industry UsageUsed in hospitals, transplant centers, and reference labs

The main difference between a Histocompatibility Laboratory Director and a Histocompatibility Laboratory Supervisor lies in their responsibilities and qualifications. The director oversees the entire laboratory, sets policies, and ensures regulatory compliance, often requiring advanced certifications and experience. The supervisor manages daily technical operations and staff, focusing on workflow and quality control. Both roles are essential in transplant immunology labs but differ in scope and level of responsibility.

What are popular job titles related to Histocompatibility Laboratory Director jobs?

For Histocompatibility Laboratory Director jobs, the most frequently searched job titles are:

Infographic showing various Histocompatibility Laboratory Director job openings in the United States as of September 2026, with employment types broken down into 100% Full Time. Highlights an 100% In-person job distribution, with an average salary of $126,086 per year, or $60.6 per hour.

Histocompatibility Laboratory Director

Hershey, PA • On-site

Penn State Health
Health Care and Social Assistance • 10K+ employees

$100K - $131K/yr

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Re-posted 8 days ago


Key responsibilities

  • Provide medical and scientific leadership for the Histocompatibility Laboratory, including oversight of HLA typing, antibody testing, and crossmatching.

  • Ensure regulatory compliance, quality assurance, and multidisciplinary collaboration within the laboratory.

  • Contribute to resident and fellow education, and support collaborative clinical or translational research.


Penn State Health rating

7.1

Company rating: 7.1 out of 10

Based on 251 frontline employees who took The Breakroom Quiz


Job description

Penn State Health - Penn State Health Medical Group LLC
Location: US:PA: Hershey
Work Type: Full Time
FTE: 1.0
Shift: Varied
Shift Differential: Exempt: Yes
Hours: Varied
Recruiter Contact: Please contact Savannah Stauffer at sstauffer@pennstatehealth.psu.edu for additional information.
Histocompatibility Laboratory Director
HERSHEY, PENNSYLVANIA (USA). Penn State Health Milton S. Hershey Medical Center and Penn State University College of Medicine are seeking an academic Histocompatibility Laboratory Director, non-tenure track, clinician-educator or clinician-scientist, open rank. Candidates with fellowship training, board certification, or substantial experience in histocompatibility, immunogenetics, transplant immunology, HLA testing, molecular diagnostics, or clinical laboratory medicine are of primary interest for this position. The successful candidate will practice at Hershey Medical Center and will provide medical and scientific leadership for the Histocompatibility Laboratory, including oversight of HLA typing, antibody testing, crossmatching, transplant-related consultative services, quality assurance, regulatory compliance, multidisciplinary collaboration, resident and fellow education, and collaborative clinical or translational research.
Board certification or eligibility in Anatomic Pathology and Clinical Pathology, Clinical Pathology, or another appropriate specialty is preferred. Candidates may be MD, DO or PhD and must be qualified or eligible to serve as director of a clinical histocompatibility laboratory and must meet applicable regulatory, accreditation, and institutional requirements for laboratory directorship. Eligibility for medical licensure in Pennsylvania is required for physician candidates. General clinical pathology service coverage will be required for MD or DO candidates. A competitive compensation plan, including a base salary, a generous incentive plan, and an excellent benefits package, are offered. The position does not offer J1 waiver or H1B sponsorship.
We are a growing subspecialty practice at the quaternary care academic hub: the Hershey Medical Center, Cancer Institute, and Children's Hospital. The successful candidate will join a strong, collegial department of 40 faculty members in Anatomic, Clinical, and Experimental Pathology and will contribute to the department's clinical pathology, laboratory medicine, transplant immunology, and histocompatibility services. The department offers a fully accredited residency program with 16 positions and four ACGME-accredited fellowship programs. Faculty members participate actively, holding several leadership roles, in undergraduate and graduate medical education, as well as graduate school teaching. Support for collaborative and independent research, including intramural funding, professional development programs, and faculty mentoring, is provided.
Hershey Medical Center lies in a particularly beautiful part of south-central PA with excellent schools, reasonable cost of living, easy commutes, and outstanding recreational opportunities. We are within 2 hours by car from major urban areas including Baltimore, DC, and Philadelphia. PSH firmly endorses a culture of respect and strongly supports diversity, equity, and belonging in its workplace.
Applications will be accepted until the position is filled and should include a letter of interest, curriculum vitae, and contact information for three individuals who could provide a reference.
Interested applicants, please send CV and Cover Letter to Savannah Stauffer at sstauffer@pennstatehealth.psu.edu. Penn State Health Hershey Medical Center is an affirmative action/equal opportunity employer. EOE-AA-M/F/D/V.
WHY PENN STATE HEALTH?
Penn State Health offers exceptional opportunities to learn and grow, exposure to a wide patient population, and the ability to provide individualized, innovative, and specialized care to patients in the community.
Penn State Health offers an exceptional benefits package including medical, dental and vision with no waiting period as well as a Total Rewards Program that highlights a few of the many additional offerings below:
  • Be Well with Employee Wellness Programs, and Fitness Discounts (University Fitness Center, Peloton).
  • Be Balanced with Generous Paid Time Off, Personal Time, and Paid Parental Leave.
  • Be Secured with Retirement, Extended Illness Bank, Life Insurance, and Identity Theft Protection.
  • Be Rewarded with Competitive Pay, Tuition Reimbursement, and PAWS UP employee recognition program.
  • Be Supported by the HR Solution Center, Learning and Organizational Development and Virtual Benefits Orientation, Employee Exclusive Concierge Service for scheduling.

WHY PENN STATE HEALTH MILTON HERSHEY MEDICAL CENTER?
Penn State Hershey Medical Center is Central Pennsylvania's only Academic Medical Center, Level 1 Regional Adult and Pediatric Trauma Center, and Tertiary Care Provider. As a four-time Magnet-designated hospital, Hershey Medical Center values the hard work and dedication that our employees exhibit every day. Through our core values of Respect, Integrity, Teamwork, and Excellence, our employees are a team committed to compassionate care for our diverse patient population, our community and each other. As a valued team member, we promote continued professional development, specialty certification, continuing education, and career growth.
YOU TAKE CARE OF THEM. WE'LL TAKE CARE OF YOU. State-of-the-art equipment, endless learning, and a culture of excellence - that's Penn State Health. But what makes our healthcare award-winning? That's all you.
This job posting is a general outline of duties performed and is not to be misconstrued as encompassing all duties performed within the position. Eligibility for shift differential pay based on the terms outlined in company policy or union contract. All individuals (including current employees) selected for a position will undergo a background check appropriate for the position's responsibilities.
Penn State Health is an Equal Opportunity Employer and does not discriminate on the basis of any protected class including disability or veteran status. Penn State Health's policies and objectives are in direct compliance with all federal and state constitutional provisions, laws, regulations, guidelines, and executive orders that prohibit or outlaw discrimination.
Union: Non Bargained

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About Penn State Health

Sourced by ZipRecruiter

Penn State Health is one of the leading teaching and research hospitals in the country. It is a multi-hospital health system, Academic Medical Center and Level 1 adult and pediatric trauma center serving patients and communities across Central Pennsylvania. The system includes Penn State Health Milton S. Hershey Medical Center, Penn State Children's Hospital, and Penn State Cancer Institute in scenic Hershey, PA. It also includes Penn State Health Saint Joseph's Medical Center in Reading, PA, Penn State Health Holy Spirit Medical Center in Camp Hill, PA, and Penn State Health Hampden Medical Center in Enola, PA. Penn State Health shares an integrated strategic plan and operations with Penn State College of Medicine.

Industry

Health care and social assistance

Company size

10,000+ Employees

Headquarters location

Hershey, PA, US

Year founded

1963

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