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How much do high throughput screening scientist jobs pay per year?

As of Aug 22, 2026, the average yearly pay for high throughput screening scientist in the United States is $122,738.00, according to ZipRecruiter salary data. Most workers in this role earn between $98,500.00 and $136,000.00 per year, depending on experience, location, and employer.

What does a high throughput screening scientist do?

A High Throughput Screening (HTS) Scientist designs, optimizes, and executes automated experiments to rapidly test thousands of chemical or biological compounds for potential activity in drug discovery or research. They develop and validate assays, operate robotic instrumentation, analyze large datasets, and collaborate with interdisciplinary teams to identify promising candidates for further study. Their work is essential in accelerating drug discovery, reducing costs, and improving efficiency in identifying potential therapeutic compounds.

What does a typical day look like for a high throughput screening scientist?

A typical day for a High Throughput Screening Scientist involves designing, executing, and analyzing high-volume biological assays to test large libraries of compounds. Scientists often split their time between the laboratory—operating robotic liquid handlers and automated screening equipment—and the office, where they interpret data and prepare reports. Collaboration is a key part of the role, as these scientists work closely with chemists, data analysts, and project managers to drive drug discovery projects forward. The work is fast-paced and dynamic, offering variety and the opportunity to contribute to groundbreaking scientific advancements.

What are the key skills and qualifications needed to thrive as a high throughput screening scientist?

To thrive as a High Throughput Screening Scientist, you generally need a background in biochemistry, molecular biology, or a related field, with experience in assay development and compound screening. Familiarity with lab automation platforms, liquid handling robotics, and data analysis software such as Spotfire or Pipeline Pilot is highly valued. Strong attention to detail, analytical thinking, and effective teamwork and communication skills help scientists excel in this collaborative environment. These capabilities are important to ensure precise, efficient experimentation, high data quality, and successful integration with larger research and development projects.

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High Throughput Screening Scientist jobs near you
Infographic showing various High Throughput Screening Scientist job openings in the United States as of August 2026, with employment types broken down into 100% Full Time. Highlights an 100% In-person job distribution, with an average salary of $122,738 per year, or $59 per hour.

Research Associate I: High-Throughput Screening

Hunter Recruiting

Boston, MA • On-site

$30 - $40/hr

Other

Re-posted 22 hours ago

Job description

Research Associate I: High-Throughput Screening

Boston, MA

$30-40/hr

6-Month


The Research Associate I will primarily work within the autonomous lab, running the plate-based screens and selections that let us evaluate thousands of engineered strains at a time.


Research Associate I Responsibilities:

  • Execute high-throughput screens and selections using the autonomous lab’s liquid-handling robotics and integrated detection instrumentation.
  • Translate assigned screening protocols into automated, code-driven workflows under the guidance of senior scientists.
  • Develop and optimize cultivation conditions and assays suited to automated execution.
  • Test screening performance, troubleshoot failed or inconsistent runs, and fl ag anomalies for root-cause investigation.
  • Maintain accurate records of screening data and protocols compatible with the lab’s automated data pipelines.


Research Associate I Requirements:

  • BS in biology, chemistry, biochemistry, chemical or biological engineering, or similar.
  • Comfort working in, or strong interest in learning to work in, an automated, high-throughput, robotics-driven laboratory environment, including software- and code-driven workflows.
  • Prior experience with plate-based assays and/or automated liquid handling a plus.
  • Prior experience using automated workflows and associated software a plus.
  • Prior experience transitioning traditional, low-throughput cloning methods into robust, high-throughput pipelines capable of generating and tracking thousands of engineered microbial strains is a plus.

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