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Full Time Weekend Rn Jobs in Orangeburg, SC (NOW HIRING)

The Rapid Response RN enhances patient safety by identifying clinical deterioration, performing ... Schedule: Full-Time; 36 hours per week; three 12-hour shifts; rotating weekends. Day shift and ...

The Rapid Response RN enhances patient safety by identifying clinical deterioration, performing ... Schedule: Full-Time; 36 hours per week; three 12-hour shifts; rotating weekends. Day shift and ...

Registered Nurse

North, SC

$40.75 - $53.25/hr

Flexible shifts including mornings, evenings, weekends, and holidays * Training may occur at a clinic other than your home location Qualifications: * RN license in the state of practice * ADN ...

Flexible shifts including mornings, evenings, weekends, and holidays * Training may occur at a clinic other than your home location Qualifications: * RN license in the state of practice * ADN ...

Flexible shifts including mornings, evenings, weekends, and holidays * Training may occur at a clinic other than your home location Qualifications: * RN license in the state of practice * ADN ...

RN On-Call Weekends

Orangeburg, SC · On-site

$70K - $80K/yr

Overview Crescent Hospice is currently seeking a Full Time On-Call Registered Nurse (RN) to join our team, providing exceptional care and support to hospice patients and their families during their ...

Flexible shifts including mornings, evenings, weekends, and holidays * Training may occur at a clinic other than your home location Qualifications: * RN license in the state of practice * ADN ...

Weekend Day: +$2.30/hr * Additional pay: Overtime Shift Details: * Schedule: 8 am-5 pm (Monday ... Licensure as a registered nurse by the South Carolina Board of Nursing or a compact state * Current ...

RN On-Call Weekends

Orangeburg, SC · On-site

$70K - $80K/yr

Overview Crescent Hospice is currently seeking a Full Time On-Call Registered Nurse (RN) to join our team, providing exceptional care and support to hospice patients and their families during their ...

Crescent Hospice is currently seeking a Full Time On-Call Registered Nurse (RN) to join our team, providing exceptional care and support to hospice patients and their families during their most ...

Day Shift, Full Time Minimum Pay : $34/hr What You'll Do: * Deliver inpatient dialysis therapies ... Schedule includes regular and on-call shifts, including weekends and holidays * Daily schedules may ...

Schedule: Full Time, Day Shift * Pay Range: $36.00 - $49.00/hr (Final determination based on ... Schedule includes regular and on-call shifts, including weekends and holidays * Daily schedules may ...

Showing results 21-40

Full Time Weekend Rn information

What is a full time weekend RN?

Full Time Weekend RNs are registered nurses who primarily work full-time hours during weekends, usually covering shifts on Fridays, Saturdays, and Sundays. These positions are common in hospitals and healthcare facilities that require round-the-clock patient care. Weekend RNs often receive premium pay rates or additional benefits due to the non-traditional work schedule. Their responsibilities are similar to other RNs, including assessing patients, administering medications, and coordinating care, but condensed into the weekend timeframe. This role is ideal for nurses seeking a work schedule that allows for weekdays off.

What are the typical weekend responsibilities and shift structures for a full time weekend RN?

Full Time Weekend RNs generally work extended shifts, such as 12-hour shifts on both Saturday and Sunday, and sometimes an additional shift on Friday or Monday, depending on the facility's needs. During these shifts, you'll handle patient assessments, medication administration, care planning, and respond to medical emergencies, often with a smaller weekend staff. Collaboration with physicians, ancillary staff, and on-call supervisors is essential to maintain continuity of care. While weekends can bring unique challenges like higher patient acuity or limited support services, many nurses appreciate the condensed schedule and the opportunity for increased autonomy.

What are the key skills and qualifications needed to thrive as a full time weekend RN, and why are they important?

To thrive as a Full Time Weekend RN, you need strong clinical skills, thorough patient assessment abilities, and a current RN license, usually supported by an accredited nursing degree. Familiarity with electronic health records (EHRs), medication administration systems, and standard hospital equipment is crucial. Outstanding interpersonal communication, time management, and resilience help nurses excel during high-demand weekend shifts. These competencies ensure effective patient care and smooth operations during times when staffing and resources may be limited.

What is the difference between Full Time Weekend Rn vs Part Time Weekend Rn?

AspectFull Time Weekend RnPart Time Weekend Rn
Work ScheduleTypically 36-40 hours per week, primarily on weekendsFewer hours, usually 8-20 hours on weekends
CredentialsRegistered Nurse (RN) license, possibly additional certificationsRegistered Nurse (RN) license, similar certifications
Work EnvironmentHospitals, clinics, or healthcare facilities with weekend shiftsSimilar settings, often with more flexible scheduling
CompensationHigher hourly rate or weekend shift differentialsLower overall pay due to fewer hours

Full Time Weekend Rns work more hours on weekends, often with benefits and higher pay, while Part Time Weekend Rns have flexible schedules with fewer hours, suitable for those seeking part-time work in healthcare settings.

What are the most commonly searched types of Weekend Rn jobs in Orangeburg, SC?

The most popular types of Weekend Rn jobs in Orangeburg, SC are:

What cities near Orangeburg, SC are hiring for Full Time Weekend Rn jobs?

Cities near Orangeburg, SC with the most Full Time Weekend Rn job openings:

Infographic showing various Full Time Weekend Rn job openings in Orangeburg, SC as of August 2026, with employment types broken down into 100% Full Time. Highlights an 100% In-person job distribution.

Rapid Response Registered Nurse

MUSC

Orangeburg, SC • On-site

Full-time, Other

Re-posted 2 days ago


MUSC Health rating

7.0

Company rating: 7.0 out of 10

Based on 201 frontline employees who took The Breakroom Quiz

414th of 888 rated healthcare providers


Job description

Job Description Summary

MUSC Orangeburg is looking for experienced Emergency or Critical Care Registered Nurses to join our NEW Rapid Response Team!
The Rapid Response RN enhances patient safety by identifying clinical deterioration, performing focused assessments, and responding to Medical Emergencies and Rapid Responses. The role supports bedside teams through collaboration, real-time education, and use of eCart and high-risk indicators.

Entity

Medical University Hospital Authority (MUHA)

Worker Type

Employee

Worker Sub-Type​

Regular

Cost Center

CC004924 ORBG - Nursing Administration

Pay Rate Type

Hourly

Pay Grade

Health-28

Scheduled Weekly Hours

36

Work Shift

Job Description

At MUSC Health - Orangeburg, we are committed to delivering safe, compassionate, and evidence-based care to every patient, every time. The Rapid Response RN plays a vital role in advancing MUSC Health’s mission by proactively identifying clinical deterioration, supporting bedside care teams, and ensuring timely escalation for high-risk patients across our inpatient settings.

This clinical expert will prioritize proactive patient rounding and focused assessments, using eCart scores, prior medical history, admission location, and other high-risk indicators to guide decision-making. In alignment with MUSC Health standards and regulatory requirements, this role evaluates patient care practices to promote quality, safety, and adherence to evidence-based practice.

The Rapid Response RN is a key collaborator within the interdisciplinary team, working closely with nursing staff, Patient Care Technicians, Hospitalist Medicine providers, Intensivists, Pulmonologists, and other clinical partners. This position responds to all Medical Emergency and Rapid Response notifications, BAT Alerts, and nurse-driven requests for evaluation. High-risk patients will be assessed each shift, with ongoing coaching and real-time education provided to support staff competency in eCart scoring, recognition of clinical deterioration, and escalation procedures.

This role supports MUSC Health’s culture of safety, accountability, and continuous improvement by monitoring and processing Key Performance Indicators (KPIs), identifying trends, and contributing to performance-improvement initiatives.

Schedule: Full-Time; 36 hours per week; three 12-hour shifts; rotating weekends. Day shift and night shift available.

Minimum Training and Experience Requirements:

Experience

  • Previous Critical Care or Emergency Department RN experience required.

  • Must demonstrate the ability to practice effectively in high-stress, fast-paced environments.

Education / Licensure / Certifications

  • Associate Degree in Nursing required; Bachelor of Science in Nursing preferred.
  • Graduate of an accredited nursing program.
  • Active South Carolina RN license required.
  • Current BLS and ACLS certifications are required.
  • Must obtain PALS, TNCC, ENPC & Safety Care certifications following hire, as part the clinical competency expectations.

Physical Requirements:

The physical demands of this role align with MUSC Health’s commitment to team member well-being and patient safety:

  • Ability to stand, walk, or sit for prolonged periods.

  • Manual dexterity and fine motor skills to perform clinical tasks safely.

  • Ability to lift, move, or reposition patients and equipment.

  • Adequate visual acuity and color perception for reading monitors, charts, and medications.

  • Sufficient hearing to communicate effectively and respond to clinical alarms.

  • Physical and emotional stamina to work long shifts and manage high-stress situations.

  • Mobility to navigate patient care units and respond rapidly to emergencies.

  • Adherence to MUSC Health infection prevention practices, including use of PPE and compliance with isolation protocols.

Additional Job Description

Minimum Training and Experience Requirements:

Experience

  • Previous Critical Care or Emergency Department RN experience required.

  • Must demonstrate the ability to practice effectively in high-stress, fast-paced environments.

Education / Licensure / Certifications

  • Associate Degree in Nursing required; Bachelor of Science in Nursing preferred.
  • Graduate of an accredited nursing program.
  • Active South Carolina RN license required.
  • Current BLS and ACLS certifications are required.
  • Must obtain PALS, TNCC, ENPC & Safety Care certifications following hire, as part the clinical competency expectations.

If you like working with energetic enthusiastic individuals, you will enjoy your career with us!

The Medical University of South Carolina is an Equal Opportunity Employer. MUSC does not discriminate on the basis of race, color, religion or belief, age, sex, national origin, gender identity, sexual orientation, disability, protected veteran status, family or parental status, or any other status protected by state laws and/or federal regulations. All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications, merit and business need.

Medical University of South Carolina participates in the federal E-Verify program to confirm the identity and employment authorization of all newly hired employees. For further information about the E-Verify program, please click here: http://www.uscis.gov/e-verify/employees


What MUSC Health employees say

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Benefits

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Workplace

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About MUSC Health

Sourced by ZipRecruiter

MUSC is located in Charleston, SC, frequently named one of the best places in America to live. If charming, historic, vibrant, cultural, and coastal are adjectives that you find appealing, it's all here. In Charleston, you might find yourself dining at a world class restaurant tonight and relaxing on a boat as you explore our many waterways tomorrow. You might stroll along cobblestone streets, amidst centuries old homes by day and attend a jazz concert by night. Charleston is a place where you can live your life to its fullest.

Industry

Hospitality services

Company size

10,000+ Employees

Headquarters location

Charleston, SC, US

Year founded

1824