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Full Time Msat Process Engineer Jobs in Boston, MA

Applied Materials

Process Engineer IV

Gloucester, MA · On-site

$128K - $176K/yr

As a Process Engineer, you'll play a crucial role in designing and optimizing manufacturing ... Time Type: Full time Employee Type: Assignee / Regular Travel: Yes, 50% of the Time Relocation ...

Moderna, Inc.

Senior Engineer I, External MSAT

Norwood, MA · On-site

$118K - $162K/yr

... process drift • Lead cross-functional troubleshooting and continuous improvement initiatives ... Strong GMP experience in a technical/engineering role within Manufacturing Operations and/or MSAT ...

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All JobsMsat Process Engineer JobsFull Time Msat Process Engineer JobsFull Time Msat Process Engineer Jobs in Boston, MA

Full Time Msat Process Engineer information

See Boston, MA salary details

$53.8K

$100K

$154.8K

How much do full time msat process engineer jobs pay per year?

As of Aug 20, 2026, the average yearly pay for full time msat process engineer in Boston, MA is $99,968.00, according to ZipRecruiter salary data. Most workers in this role earn between $80,900.00 and $111,900.00 per year, depending on experience, location, and employer.

What is the difference between Full Time Msat Process Engineer vs Full Time Semiconductor Process Engineer?

AspectFull Time Msat Process EngineerFull Time Semiconductor Process Engineer
CredentialsBachelor's in Engineering or related field, certifications in process engineeringBachelor's or higher in Electrical, Chemical, or Materials Engineering, certifications in process or manufacturing
Work EnvironmentCleanroom manufacturing, R&D labs, production facilitiesCleanroom fabs, R&D labs, manufacturing plants
Industry UsagePrimarily in semiconductor manufacturing, especially in MSAT (Manufacturing Science and Technology)Broader semiconductor industry, including fabrication, testing, and assembly

While both roles focus on process optimization within semiconductor manufacturing, the Full Time Msat Process Engineer specializes in manufacturing science and technology processes, often emphasizing process development and troubleshooting. The Full Time Semiconductor Process Engineer has a broader scope, covering various fabrication and process steps across the semiconductor industry. Both roles require similar technical skills and work in cleanroom environments, but their specific focus areas differ slightly.

What is a full time Msat process engineer?

A full-time MSAT (Manufacturing Science and Technology) process engineer is responsible for developing, optimizing, and maintaining manufacturing processes for semiconductor or pharmaceutical products. They analyze process data, troubleshoot issues, and implement improvements to ensure product quality and efficiency, often using tools like statistical analysis and process control. This role typically requires a strong background in engineering, chemistry, or related fields, and may involve working in cleanroom environments or manufacturing facilities.

What are the most commonly searched types of Msat Process Engineer jobs in Boston, MA?

The most popular types of Msat Process Engineer jobs in Boston, MA are:

What are popular job titles related to Full Time Msat Process Engineer jobs in Boston, MA?

For Full Time Msat Process Engineer jobs in Boston, MA, the most frequently searched job titles are:

What job categories do people searching Full Time Msat Process Engineer jobs in Boston, MA look for?

The top searched job categories for Full Time Msat Process Engineer jobs in Boston, MA are:

Full Time Msat Process Engineer jobs near you
Infographic showing various Full Time Msat Process Engineer job openings in Boston, MA as of August 2026, with employment types broken down into 1% As Needed, 78% Full Time, 16% Part Time, 4% Contract, and 1% Nights. Highlights an 92% Physical, 2% Hybrid, and 6% Remote job distribution, with an average salary of $99,968 per year, or $48.1 per hour.

Executive Director, MSAT - Type 1 Diabetes

Vertex Pharmaceuticals

Boston, MA • On-site

Full-time

Medical, Dental, Vision, Retirement, PTO

Re-posted 26 days ago

Vertex Pharmaceuticals rating

6.5

Company rating: 6.5 out of 10

Based on 5 frontline employees who took The Breakroom Quiz

78th of 86 rated pharmaceutical

Job description

Job Description
General Summary:
At Vertex, we're driven by a shared purpose: to transform the lives of patients with serious diseases. The Executive Director, MSAT will provide strategic and hands-on leadership for Manufacturing Science & Technology (MSAT) across our Type 1 Diabetes cell therapy manufacturing network. This role is accountable for process performance, technical transfer, validation, continued process verification, comparability, and lifecycle management-with a particular focus on external manufacturing partners (CMOs).
You will build and lead a high-performing MSAT organization that bridges Process Development and GMP Manufacturing, ensuring processes are robust, scalable, compliant, and inspection-ready from early clinical supply through commercialization. This is a highly cross-functional leadership position partnering with Technical Operations, Quality, CMC, Regulatory, Supply Chain, and external manufacturing partners.
Key Duties and Responsibilities:
MSAT Strategy & Network Leadership
  • Define and execute the MSAT strategy for T1D cell therapy manufacturing across a global external network, ensuring technical readiness for clinical development and commercial launch.
  • Establish and lead governance models for MSAT engagement with CMOs and co-invested sites, including joint technical forums, escalation pathways, and performance metrics.
  • Set technical standards and harmonized approaches across sites for process control, process validation, deviation management, and lifecycle improvements.

Tech Transfer & Manufacturing Readiness
  • Partner with Process Development to ensure right-first-time technology transfer into external manufacturing sites, ensuring operationalization of process knowledge, documentation readiness, and training for GMP execution.
  • Drive integrated readiness plans for pivotal trials and commercial launch: facility fit, equipment strategy, material qualification, batch records, and manufacturing execution (paper/eBR/MES).
  • Ensure robust site onboarding and sustained technical engagement-acting as the technical lead for process execution performance.

Process Characterization, Control Strategy & Validation
  • Own and evolve the control strategy in partnership with CMC, Quality, and Regulatory, ensuring scientifically sound and phase-appropriate controls.
  • Lead process validation/PPQ strategies, including sampling plans, acceptance criteria, statistical approaches, and continued verification.
  • Ensure alignment of critical process parameters (CPPs), critical quality attributes (CQAs), and in-process controls across sites.

Continued Process Verification (CPV), Trending & Operational Excellence
  • Build a best-in-class CPV and trending program across the network: yield, purity, potency, viability, cycle time, deviations, and release performance.
  • Lead investigations and technical risk assessments for major deviations, OOS/OOT, and atypical events-ensuring timely root cause, effective CAPAs, and sustained improvements.
  • Drive continuous improvement through process optimization, standardization, and lean problem solving, while maintaining compliance.

Change Control, Comparability & Lifecycle Management
  • Lead technical assessment and execution of change control across external sites (process, analytical, equipment, raw materials, suppliers).
  • Own comparability strategies for process changes and site transfers, ensuring robust data packages for regulatory submissions and inspection readiness.
  • Partner with Regulatory CMC to support IND/BLA/MAA content, HA questions, and commitments related to process and control strategy.

Materials, Raw Materials & Supplier Technical Oversight
  • Provide MSAT leadership for material qualification, supplier changes, and risk management (critical raw materials, reagents, single-use systems).
  • Partner with Supply Chain and Quality to ensure technical oversight for supplier network robustness, including dual sourcing strategies where appropriate.

Digital, Automation & Data Systems Enablement
  • Champion digital enablement of manufacturing-MES/eBR, historian integration, data pipelines, and analytics to improve right-first-time execution.
  • Promote automation and closed-system solutions where feasible to enhance robustness, reduce variability, and improve scalability.

People Leadership & Vertex Culture
  • Build, mentor, and lead a high-impact MSAT organization across disciplines (process engineers, tech transfer leads, validation engineers, data/trending experts).
  • Foster a culture of scientific rigor, transparency, collaboration, and urgency for patients-balancing speed with quality and compliance.

Knowledge and Skills:
Technical Expertise
  • Deep understanding of GMP expectations for advanced therapies and late-stage readiness (validation, CPV, inspection readiness).
  • Proven capability in control strategy development, process characterization, and lifecycle management.
  • Strong experience with deviations/investigations, change control, and comparability strategies across multi-site networks.
  • Working knowledge of analytics strategy interface (method readiness, tech transfer, comparability support) and how it ties to product control.

Leadership & Influence
  • Demonstrated ability to lead through influence in complex, matrixed organizations and across external partner boundaries.
  • Strong executive communication skills with the ability to simplify complexity, drive alignment, and make risk-based decisions.
  • Track record of building high-performing teams and developing technical talent.

Education and Experience:
  • Advanced degree (MS/PhD preferred) in Chemical Engineering, Biomedical Engineering, Biotechnology, Life Sciences, or related discipline.
  • 15+ years of biopharmaceutical experience with progressive leadership in MSAT/Manufacturing/Process Engineering roles.
  • Significant experience in cell therapy and/or advanced biologics manufacturing; experience supporting both clinical and commercial programs strongly preferred.
  • Demonstrated success leading external manufacturing tech transfers and operating in CMO-centric or hybrid manufacturing models.

Pay Range:
$249,400 - $374,200
Disclosure Statement:
The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.
At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.
Flex Designation:
On-Site Designated
Flex Eligibility Status:
In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility.
Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time.
#LI-Onsite
Company Information
Vertex is a global biotechnology company that invests in scientific innovation.
Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

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