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Full Time Downstream Process Development Scientist Jobs in Raleigh, NC

MedPharm

Process Technician

Durham, NC · On-site

Process Development/ Formulation R&D * Facilities Travel requirements: • No Education and Experience: * A.A.S. in a scientific discipline, or equivalent experience preferred * 2-4 years' experience ...

MedPharm

Process Technician

Durham, NC · On-site

Process Development/ Formulation R&D * Facilities Travel requirements: · No Education and Experience: * A.A.S. in a scientific discipline, or equivalent experience preferred * 2-4 years' experience ...

KBI Biopharma, Inc.

Scientist I

Durham, NC · On-site

$84K - $115K/yr

Collaborate cross-functionally with process development, manufacturing, program management, data review, and quality assurance teams. * Mentor and train junior scientists and associates. * Perform ...

KBI Biopharma, Inc.

Scientist I

Durham, NC · On-site

$84K - $115K/yr

Collaborate cross-functionally with process development, manufacturing, program management, data review, and quality assurance teams. * Mentor and train junior scientists and associates. * Perform ...

Vulcan Elements

Process Engineer

Durham, NC

Process Development & Qualification: Run engineering trials to determine optimal equipment recipes ... Bachelor's degree in Chemical Engineering, Materials Science, Industrial Engineering, Mechanical ...

KBI Biopharma, Inc.

Associate Scientist

Durham, NC · On-site

$76K - $95K/yr

At KBI Biopharma, we are advancing science and accelerating breakthroughs. As a global leader in ... Recognized for quality manufacturing, KBI delivers robust process development and cGMP ...

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All JobsDownstream Process Development Scientist JobsFull Time Downstream Process Development Scientist JobsFull Time Downstream Process Development Scientist Jobs in Raleigh, NC

Full Time Downstream Process Development Scientist information

See Raleigh, NC salary details

$20

$37

$59

How much do full time downstream process development scientist jobs pay per hour?

As of Jul 10, 2026, the average hourly pay for full time downstream process development scientist in Raleigh, NC is $37.58, according to ZipRecruiter salary data. Most workers in this role earn between $27.60 and $44.86 per hour, depending on experience, location, and employer.

What does a Full Time Downstream Process Development Scientist do?

A Full Time Downstream Process Development Scientist is responsible for designing, optimizing, and scaling up processes that purify biological products such as proteins, antibodies, or vaccines after they are produced in cells or microbes. This role involves developing and improving techniques like filtration, chromatography, and centrifugation to ensure high purity and yield of the final product. The scientist also conducts experiments, analyzes data, and collaborates with cross-functional teams to transfer processes from the lab to manufacturing. Their work is critical for producing safe and effective biopharmaceuticals on a large scale.

What is the difference between Full Time Downstream Process Development Scientist vs Downstream Process Engineer?

AspectFull Time Downstream Process Development Scientist
Primary FocusDesigning, optimizing, and developing downstream purification processes for biopharmaceuticals
Required CredentialsBachelor's or Master's in Biotechnology, Biochemistry, or related field; experience in process development
Work EnvironmentLaboratories, R&D settings, collaborative teams in biotech or pharma companies
Typical ResponsibilitiesProcess scale-up, method validation, troubleshooting, documentation

While both roles involve downstream bioprocessing, the Full Time Downstream Process Development Scientist focuses on process development and optimization, whereas the Downstream Process Engineer typically handles process implementation and manufacturing support. The scientist role emphasizes research and development, while the engineer role is more operational. Candidates often hold similar degrees and certifications, but their daily tasks and focus areas differ.

What are some typical challenges faced by a Downstream Process Development Scientist, and how can they be addressed?

Downstream Process Development Scientists often encounter challenges such as optimizing protein purification processes to achieve high yield and purity, troubleshooting unexpected impurities, and scaling up processes from laboratory to manufacturing scale. These tasks require strong problem-solving skills, meticulous attention to detail, and effective collaboration with upstream teams, analytical scientists, and manufacturing staff. Addressing these challenges involves staying current with new purification technologies, maintaining robust documentation, and participating in cross-functional meetings to ensure seamless process integration and regulatory compliance.

What are the key skills and qualifications needed to thrive as a Full Time Downstream Process Development Scientist, and why are they important?

To thrive as a Full Time Downstream Process Development Scientist, you need a strong background in biochemical engineering, protein purification, and analytical techniques, typically supported by a degree in biochemistry, biotechnology, or a related field. Proficiency with chromatography systems (e.g., HPLC, FPLC), filtration technologies, and knowledge of regulatory and quality systems like GMP is essential. Strong problem-solving abilities, teamwork, and effective communication skills help you collaborate with cross-functional teams and troubleshoot process challenges. These skills are crucial for developing robust purification processes that ensure product quality, regulatory compliance, and efficient production in biopharmaceutical environments.
What are the most commonly searched types of Downstream Process Development Scientist jobs in Raleigh, NC? The most popular types of Downstream Process Development Scientist jobs in Raleigh, NC are:
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What cities near Raleigh, NC are hiring for Full Time Downstream Process Development Scientist jobs? Cities near Raleigh, NC with the most Full Time Downstream Process Development Scientist job openings:
Full Time Downstream Process Development Scientist jobs near you
Infographic showing various Full Time Downstream Process Development Scientist job openings in Raleigh, NC as of July 2026, with employment types broken down into 100% Full Time. Highlights an 100% In-person job distribution, with an average salary of $78,175 per year, or $37.6 per hour.
Process Technician

Process Technician

MedPharm

Durham, NC • On-site

Full-time

Re-posted 26 days ago

Job description

Position Summary
The Manufacturing Operator is responsible for executing a wide range of operations in a cGMP-compliant biopharmaceutical manufacturing environment. This role involves operating, maintaining, and troubleshooting production equipment, performing and documenting complex and critical processes, and supporting equipment validation activities. The operator ensures compliance with standard operating procedures, safety regulations, and documentation standards while contributing to continuous improvement initiatives. Ideal candidates will have an A.A.S. in scientific discipline or equivalent experience, along with 2-4 years of hands-on manufacturing experience. The role also requires strong communication skills, proficiency with MS Office and electronic systems, and the ability to adapt in a dynamic team environment while meeting strict quality and safety standards.
Essential Functions:
  • Operate manufacturing equipment and instruments.
  • Complete assigned tasks in a timely manner.
  • Conduct daily activities in an organized, efficient manner.
  • Perform simple, routine, complex, and critical operations.
  • Troubleshoot equipment issues, when necessary.
  • Ensure process equipment is appropriately maintained for operation.
  • Perform and document operations in accordance with cGMP's.
  • Execute equipment qualification protocols and validation protocols.
  • Recognize and initiate process deviations.
  • Support continuous improvement initiatives by identifying areas needing improvement, recommending strategies for improvement, and implementing those strategies once approved.
  • Communicate effectively, both in written and verbal formats.
  • Maintain training compliance. Ensure a safe working environment for all staff.

Supervisory responsibilities:
  • Direct Reports: No
  • Indirect Reports: No

Key Relationships (examples: Depts or Individual positions that this position will be working closely with):
  • Quality Control
  • Quality Assurance
  • Process Development/ Formulation R&D
  • Facilities

Travel requirements:
• No
Education and Experience:
  • A.A.S. in a scientific discipline, or equivalent experience preferred
  • 2-4 years' experience in a cGMP biopharmaceutical manufacturing environment required
  • Previous experience as subject matter expert and training others
  • Existing knowledge of equipment in a manufacturing/production environment

Knowledge, Skills, and Abilities:
  • Must be able to work within and adapt to electronic systems
  • Able to function, with guidance, in a rapidly changing environment while balancing multiple priorities simultaneously
  • Must be able to be PAPR and Respirator qualified
  • Able to work independently and as part of a team
  • Must be able to read, write and converse in English
  • Must have a good working knowledge of MS Office (Outlook, Word and Excel)

Physical Demands and Work Environment:
While performing the duties of this job, there may be certain physical demands required for the position.
  • Requires constant standing, walking, seeing, & hearing
  • Requires occasional sitting
  • Requires constant carrying & lifting; frequently under 20 LBS, 20-60 LBS, & occasionally over 60 lbs
  • Requires frequent bending, twisting, gripping, & reaching
  • Requires frequent pushing & pulling under 20 LBS, 20-60 LBS, & occasionally over 60 LBS

Other Duties:
You may be asked to take on any other responsibilities or tasks that are within your skills and abilities whenever reasonably asked.

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