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Full Time Downstream Process Development Scientist Jobs in Michigan

Biovire

Manager, Process Development

Brighton, MI · On-site

Manager, Process Development Engineering Organization Brighton, Michigan Biovire is advancing ... life science or technical discipline required. * Graduate degree in Chemistry, Biochemistry ...

Biovire

Manager, Process Development

Brighton, MI · On-site

$100K - $120K/yr

Manager, Process Development Engineering Organization Brighton, Michigan Biovire is advancing ... life science or technical discipline required. * Graduate degree in Chemistry, Biochemistry ...

Biovire

Manager, Process Development

Brighton, MI · On-site

$100K - $120K/yr

We are seeking a Manager, Process Development to lead technical transfer activities for sterile ... science or technical discipline required.Graduate degree in Chemistry, Biochemistry, Molecular ...

BEL

Senior R&D Scientist

Grawn, MI · On-site

$100K - $127K/yr

On-site work Job Id: 54025 Senior R&D Scientist Bel is part of a mission-driven, family-owned ... Develop recipes and process parameters at bench, pilot, and industrial scale while ensuring ...

Bel

Senior R&D Scientist

Traverse City, MI · On-site

$90K - $100K/yr

On-site work Job Id: 54025 Senior R&D Scientist Bel is part of a mission-driven, family-owned ... Develop recipes and process parameters at bench, pilot, and industrial scale while ensuring ...

Evotec

$84K - $115K/yr

Senior Scientist - Biofermentation & Process Development About Us: this is who we are At Evotec , we believe that curiosity is the spark that drives innovation and success. As a forward-thinking team ...

New

Legend Biotech US

Execute lentiviral vector (LVV) downstream process development activities, including the design ... These benefits are offered exclusively to permanent full-time employees. Contractors are not ...

New

Merck

$117K - $184K/yr

Senior Scientist - Process Analytical Technologies (PAT) We are seeking a Senior Scientist to join ... Analytical Method Development, Assay Development, Chromatographic Techniques, GMP Environments ...

New

MSD

$117K - $184K/yr

Senior Scientist - Process Analytical Technologies (PAT) We are seeking a Senior Scientist to join ... Analytical Method Development, Assay Development, Chromatographic Techniques, GMP Environments ...

New

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All JobsDownstream Process Development Scientist JobsFull Time Downstream Process Development Scientist JobsFull Time Downstream Process Development Scientist Jobs in Michigan

Full Time Downstream Process Development Scientist information

What does a full time downstream process development scientist do?

A Full Time Downstream Process Development Scientist is responsible for designing, optimizing, and scaling up processes that purify biological products such as proteins, antibodies, or vaccines after they are produced in cells or microbes. This role involves developing and improving techniques like filtration, chromatography, and centrifugation to ensure high purity and yield of the final product. The scientist also conducts experiments, analyzes data, and collaborates with cross-functional teams to transfer processes from the lab to manufacturing. Their work is critical for producing safe and effective biopharmaceuticals on a large scale.

What are the key skills and qualifications needed to thrive as a full time downstream process development scientist, and why are they important?

To thrive as a Full Time Downstream Process Development Scientist, you need a strong background in biochemical engineering, protein purification, and analytical techniques, typically supported by a degree in biochemistry, biotechnology, or a related field. Proficiency with chromatography systems (e.g., HPLC, FPLC), filtration technologies, and knowledge of regulatory and quality systems like GMP is essential. Strong problem-solving abilities, teamwork, and effective communication skills help you collaborate with cross-functional teams and troubleshoot process challenges. These skills are crucial for developing robust purification processes that ensure product quality, regulatory compliance, and efficient production in biopharmaceutical environments.

What are some typical challenges faced by a full time downstream process development scientist, and how can they be addressed?

Downstream Process Development Scientists often encounter challenges such as optimizing protein purification processes to achieve high yield and purity, troubleshooting unexpected impurities, and scaling up processes from laboratory to manufacturing scale. These tasks require strong problem-solving skills, meticulous attention to detail, and effective collaboration with upstream teams, analytical scientists, and manufacturing staff. Addressing these challenges involves staying current with new purification technologies, maintaining robust documentation, and participating in cross-functional meetings to ensure seamless process integration and regulatory compliance.

What is the difference between Full Time Downstream Process Development Scientist vs Downstream Process Engineer?

AspectFull Time Downstream Process Development Scientist
Primary FocusDesigning, optimizing, and developing downstream purification processes for biopharmaceuticals
Required CredentialsBachelor's or Master's in Biotechnology, Biochemistry, or related field; experience in process development
Work EnvironmentLaboratories, R&D settings, collaborative teams in biotech or pharma companies
Typical ResponsibilitiesProcess scale-up, method validation, troubleshooting, documentation

While both roles involve downstream bioprocessing, the Full Time Downstream Process Development Scientist focuses on process development and optimization, whereas the Downstream Process Engineer typically handles process implementation and manufacturing support. The scientist role emphasizes research and development, while the engineer role is more operational. Candidates often hold similar degrees and certifications, but their daily tasks and focus areas differ.

How much does a full time downstream process development scientist make?

In California, a full-time downstream process development scientist typically earns between $80,000 and $130,000 annually, depending on experience, education, and the specific employer. Salaries may also include benefits such as health insurance and bonuses, with higher compensation often associated with advanced skills in bioprocessing and laboratory techniques.

What is a full time downstream process development scientist?

A full-time downstream process development scientist specializes in designing, optimizing, and scaling the purification processes used in biopharmaceutical manufacturing, such as chromatography and filtration. They work to improve product yield, purity, and efficiency, often using laboratory techniques and process modeling tools, typically within a regulated environment requiring compliance with industry standards.

What are the most commonly searched types of Downstream Process Development Scientist jobs in Michigan?

The most popular types of Downstream Process Development Scientist jobs in Michigan are:

What are popular job titles related to Full Time Downstream Process Development Scientist jobs in Michigan?

For Full Time Downstream Process Development Scientist jobs in Michigan, the most frequently searched job titles are:

What job categories do people searching Full Time Downstream Process Development Scientist jobs in Michigan look for?

The top searched job categories for Full Time Downstream Process Development Scientist jobs in Michigan are:

What cities in Michigan are hiring for Full Time Downstream Process Development Scientist jobs?

Cities in Michigan with the most Full Time Downstream Process Development Scientist job openings:

Full Time Downstream Process Development Scientist jobs near you

Process Development Scientist

Piramal Pharma Limited

Riverview, MI • On-site

Full-time

Re-posted 18 days ago

Job description

Be the First to Apply

Division

Piramal Pharma Solutions

Piramal Pharma Solutions is a contract development and manufacturing organization (CDMO), offering end-to-end development and manufacturing solutions across the drug life cycle. We serve our clients through a globally integrated network of facilities in North America, Europe and Asia.

This enables us to offer a comprehensive range of services including Drug Discovery Solutions, Process & Pharmaceutical Development services, Clinical Trial Supplies, Commercial supply of APIs and Finished dosage forms. We also offer specialized services like development and manufacture of Highly Potent APIs and Antibody Drug Conjugation.

Our capability as an integrated service provider & experience with various technologies enables us to serve Innovator and Generic companies worldwide.

For more details, please visit : www.piramalpharmasolutions.com

Job Title

Process Development Scientist

Job Description

Piramal Pharma Solutions' HPAPI Research and Manufacturing facility, located in Riverview, Michigan, is seeking a qualified Process Development Scientist to join our Process Development team. The PD Scientist is responsible for the development of current and new manufacturing processes.

Key responsibilities.

  • Develop, conduct, and/or manage the process development of current and new synthetic/process pathways including routine analytical testing to monitor process progress (HPLC, NMR, XRPD, GC-HS, KF, etc.).
  • Handling of highly potent compounds and experience in synthesis and handling of Linker-Payloads is highly desirable.
  • Scale-up preparative HPLC purification and lyophilization of intermediates and final products.
  • Maintain communications with clients and ensure their requirements are met.
  • Manage/support the production of new (HP)APIs. Ensure that adequate supplies of process materials (raw materials, solvents, reagents, etc.) and operation equipment (hoses, reactors, glassware, etc.) are available for assigned tasks.
  • Ensure that product shipments meet customer and regulatory (FDA, EPA, OSHA, etc.) requirements.
  • Write progress reports and provide technical support in meetings regarding current API production and new API process development.
  • Ensure that approved processes are carried out according to cGMP guidelines and are properly documented.
  • Keep Quality Assurance and Quality Control departments updated in regard to project/client requirements and schedules. Participate in the development, training, and transfer of new processes into the plant. Maintain accurate inventories of materials.
  • Prepare appropriate reports as needed for management and/or clients.
  • Maintain notebooks for research and development and non-GMP activities. Complete and audit production and cleaning records. Complete logbooks and documentation (dispensing record, BPRs, cleaning records, deviation reports, etc.) related to production and cleaning is accordance with regulatory requirements.
  • Generate and/or evaluate standard operating procedures as required.
  • Provide technical support for chemical operators, engineering, quality control, etc.

EDUCATION/EXPERIENCE

  • To be qualified as a PD Scientist, a candidate must have:
    • PhD in Organic or Medicinal Chemistry and up to four (4) years' experience in a relevant field; OR
    • MS in Organic or Medicinal Chemistry and up to eight (8) years' experience in a relevant field; OR
    • BS in Organic or Medicinal Chemistry and up to twelve (12) years' experience in a relevant field
  • Knowledge of organic chemistry and chemical safety.

job competencies.

  • Excellent organizational and planning skills.
  • Strong written, verbal, and interpersonal communication skills.
  • Self-motivated, creative, and independent.
  • Ability to direct projects covering a variety of chemical compounds including high potent APIs.
  • Familiarity with cGMP, plant safety, and EPA requirements.

Apply