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Full Time Bioinformatics Software Engineer Jobs in California

Probably Genetic

Senior Software Engineer

San Francisco, CA · On-site

$150K - $210K/yr

  • Medical

  • Dental

  • Vision

  • Retirement

About the Role We are looking for a Senior Software Engineer who will contribute to the design and ... Create APIs, laboratory integrations, bioinformatic tooling, and ML infrastructure using Python ...

Valius Sciences

Full-stack Software Engineer

San Francisco, CA · On-site

$200K - $300K/yr

  • Medical

  • Dental

  • Vision

  • Retirement

We're building the diagnostics and bioinformatics company to power this future, starting by ... Software engineer role We're hiring a software engineer to build the infrastructure and products ...

Illumina

Staff Software Engineer

San Diego, CA · Hybrid

  • Medical

  • Dental

  • Vision

  • Retirement

  • PTO

Closely interact with the bioinformatics team, instrument design team, test and quality teams ... Software Engineer role based in the United States of America is: $155,600 - $233,400. Should the ...

Profluent

Lead Bioinformatics Scientist, NGS

Emeryville, CA · On-site +1

$160K - $230K/yr

  • Medical

  • Dental

  • Vision

  • Retirement

  • PTO

You'll also mentor team members, promote software engineering best practices, and help shape the future of Profluent's computational biology capabilities. Responsibilities * Lead design and ...

Illumina, Inc.

Staff Software Engineer

San Diego, CA · On-site

  • Medical

  • Dental

  • Vision

  • Retirement

  • PTO

Closely interact with the bioinformatics team, instrument design team, test and quality teams ... Software Engineer role based in the United States of America is: $155,600 - $233,400. Should the ...

BillionToOne

Quality Engineer, Prenatal

Union City, CA · On-site

$82K - $105K/yr

  • Medical

  • Retirement

  • PTO

Lab Operations, Bioinformatics, Process Engineering, Software Engineering, R&D). You will lead the analysis of data to identify improvement initiatives and will execute those process improvements ...

Natera

Principal Software Engineer

South San Francisco, CA · On-site

$162K - $217K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Remote optional Job Type: Full-time About the Role We're seeking a Principal Software Engineer to ... or bioinformatics computing, LIMS or laboratory data systems, workflow orchestration engines ...

Natera

Principal Software Engineer

South San Francisco, CA · Remote

$162K - $217K/yr

Remote optional Job Type: Full-time About the Role We're seeking a Principal Software Engineer to ... or bioinformatics computing, LIMS or laboratory data systems, workflow orchestration engines ...

GATC Health

Bioinformatics Analyst - CA

Irvine, CA · On-site

... software development methods and tools in a team environment. • Experience in programming in ... and bioinformatics innovation. Company : GATC Health uses AI to speed drug discovery, predict ...

Natera

Director of Data Science and Bioinformatics

San Carlos, CA · On-site

$195K - $244K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Build and define the Bioinformatics function within the Data Science development team, identify ... business professionals, software engineers and many other professionals from world-class ...

Mithrl

Bioinformatics Engineer, Pipelines

San Francisco, CA · On-site

$150K - $200K/yr

  • Medical

  • Dental

  • Vision

  • Retirement

ABOUT THE ROLE We are looking for a Lead Bioinformatics Pipeline Engineer to build and scale Mithrl ... Previous work in a tech bio startup, biotech R&D group, or scientific software company WHAT YOU ...

Profluent

Senior Software Engineer, Data Platform

Emeryville, CA · On-site +1

$132K - $159K/yr

  • Medical

  • Dental

  • Vision

  • Retirement

  • PTO

You will work closely with ML, bioinformatics, and program teams to ensure Profluent's data is ... * 5+ years of software engineering, data engineering, or data platform experience * Strong ...

Mithrl

Bioinformatics Engineer, Pipelines

San Francisco, CA · On-site

$150K - $200K/yr

  • Medical

  • Dental

  • Vision

  • Retirement

ABOUT THE ROLE We are looking for a Lead Bioinformatics Pipeline Engineer to build and scale Mithrl ... Previous work in a tech bio startup, biotech R&D group, or scientific software company WHAT YOU ...

Research and Testing Laboratory

Sr Software Engineer

San Diego, CA · On-site

$130K - $171K/yr

  • Medical

  • Dental

  • Vision

  • Retirement

  • PTO

We are looking for an experienced software engineer to join our Instrument Software team. This team ... Experience with NGS and Bioinformatics is a plus. Additional Skills: * Proven track record of ...

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Full Time Bioinformatics Software Engineer information

What is the difference between Full Time Bioinformatics Software Engineer vs Bioinformatics Data Analyst?

AspectFull Time Bioinformatics Software EngineerBioinformatics Data Analyst
Required CredentialsBachelor's or Master's in Bioinformatics, Computer Science, or related field; programming skillsBachelor's or Master's in Bioinformatics, Biology, or related field; data analysis skills
Work EnvironmentDevelops software tools, algorithms, and pipelines in research or industry labsAnalyzes biological data, generates reports, and visualizations in research or healthcare settings
Employer & Industry UsageTech companies, biotech firms, research institutionsHealthcare providers, research labs, pharmaceutical companies

Full Time Bioinformatics Software Engineers focus on developing software solutions and algorithms, while Bioinformatics Data Analysts primarily interpret biological data and generate insights. Both roles require strong computational skills but differ in their core responsibilities and daily tasks.

Is a full time bioinformatics software engineer still a viable career?

A full-time bioinformatics software engineer remains a viable career due to ongoing advancements in genomics, personalized medicine, and data analysis. The role requires skills in programming, data management, and familiarity with tools like Python, R, and Linux, with demand driven by research institutions, biotech companies, and healthcare organizations.

What are the most commonly searched types of Bioinformatics Software Engineer jobs in California?

The most popular types of Bioinformatics Software Engineer jobs in California are:

What are popular job titles related to Full Time Bioinformatics Software Engineer jobs in California?

For Full Time Bioinformatics Software Engineer jobs in California, the most frequently searched job titles are:

What job categories do people searching Full Time Bioinformatics Software Engineer jobs in California look for?

The top searched job categories for Full Time Bioinformatics Software Engineer jobs in California are:

Full Time Bioinformatics Software Engineer jobs near you
Infographic showing various Full Time Bioinformatics Software Engineer job openings in California as of August 2026, with employment types broken down into 100% Full Time. Highlights an 95% In-person, and 5% Hybrid job distribution.

Senior Software Engineer

Probably Genetic

San Francisco, CA • On-site

$150K - $210K/yr

Full-time

Medical, Dental, Vision, Retirement

Re-posted 4 days ago

Job description

About Probably Genetic
Probably Genetic is changing the lives of patients living with severe, complex diseases. Our data platform is used by drug developers and patient advocacy groups to develop and launch treatments for these patients. Our technology discovers undiagnosed patients online, analyzes their disease state using machine learning and at-home testing, and enables compliant communication with patients. In doing so, we help patients access diagnoses, clinical trials, and treatments as early as possible.
We are a tight-knit group of hard-working, ambitious problem solvers united by a mission greater than ourselves. We do well by doing right by patients. We are developing some of the most cutting-edge solutions in healthcare, and our roadmap is packed with innovations in bioinformatics, AI, and drug development. We have built a lean, all-star team to help us bring our vision to life, and we want you to be a part of it.
Probably Genetic has raised multiple rounds of funding from Silicon Valley's best investors, including Threshold, Khosla, and Y Combinator, and offer competitive salaries, comprehensive benefits, and meaningful early stage equity.
About the Role
We are looking for a Senior Software Engineer who will contribute to the design and implementation of our AI-enabled patient experience, genetic sequencing workflows, and help enable the critical infrastructure needed to support a world-class patient intelligence platform. Come build with us and make a real difference in the lives of our patients!
What you will do
  • Work across teams to rapidly transform key requirements into front-end releases that meaningfully improve how patients engage with our product
  • Create APIs, laboratory integrations, bioinformatic tooling, and ML infrastructure using Python, Django, PostgreSQL databases, and AWS services
  • Develop the phenotyping product and biotech data platform frontends in React & Typescript
  • Regularly review your team's pull requests and technical proposal documents to maintain high standards and architectural quality
  • Present your work to relevant stakeholders, monitoring outcomes, and integrating patient feedback
  • Contribute to a culture of continuous improvement at a high velocity by optimizing development processes
  • Own business goals and writing technical design specifications to find more patients, grow revenue, and increase margins
  • Collaborate with Product and other business teams to implement solutions which drive customer value
  • Work with cross-functional stakeholders to refine business processes and develop software to automate those processes
Who you are
We are looking for a few specific things that will help you succeed in this role:
  • Proven experience developing full-stack applications, with a front-end focus and a passion for shipping high quality code at velocity
  • Experience in a range of software languages and frameworks included in our tech stack:
    • Languages: Python (Django) and Typescript (React)
    • Tools/Infrastructure: PostgreSQL, AWS, Terraform, GitHub Actions
  • Experience designing and building scalable systems used by external users
  • Track-record of solving extremely difficult, ambiguous problems
  • Excellent communication skills with ability to can convey your ideals clearly to engineers and non-engineers alike!
Some things that are not required, but you will learn on the job:
  • Expertise with healthcare data, bioinformatics, genetics, ML infrastructure, or growth marketing
  • Expertise in HIPAA compliance and security best practices
  • Expertise in product development practices such as user interviews and product analytics
As with all new hires at Probably Genetic, you will also need to be:
  • A good person. We work with some of the most marginalized populations on the planet and empathy is key.
  • Patient-focused and motivated to have a lasting, positive impact on humanity.
  • Comfortable in a fast-paced, often ambiguous environment with rapid change.
  • Action-oriented and excited to build a company from the ground up.

The salary range for this role is $150,000-$210,000 annually. Actual compensation offered will depend on several factors including but not limited to: work experience, education, skill level, and/or other business and organizational needs.
This is a hybrid role that will requires working on-site 3 days a week (Tuesday, Wednesday, Thursday) in San Francisco and we are open to relocation.
What we offer at Probably Genetic:
  • An engaging and supportive team all on a mission to improve lives
  • Fair and equitable compensation with competitive early-stage equity grants
  • Generous Flexible Time off policy, that we actually use
  • Parental Leave Benefits (12 weeks for both birthing and non-birthing)
  • Hybrid, flexible work with high-trust and autonomy
  • A bright, inviting, pet-friendly office in Downtown SF near transit
  • A "work from anywhere" policy, up to 4 weeks a year
  • Regular team retreats in exciting destinations
  • Health Benefits including medical, dental, vision, therapy, FSA, and 401k
  • And so much more!

Probably Genetic is committed to fostering a welcoming and inclusive work environment for people of all genders, sexuality, ethnicity, socioeconomic background and life experiences. We urge candidates of all backgrounds to apply. If you require specific accommodations as you interview or consider working with us, please let us know.

Apply