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Senior Scientist, Formulation and DP Development

Sutro Biopharma, Inc. is looking for a technical leader who will report to the Executive Director of Formulation and DP Development. You will be developing new compositions for biologic / conjugated molecules and creating robust DP manufacturing processes to advance Sutro pipeline and enhance our internal and collaborative product development initiatives in a fast-paced environment.

Responsibilities:

The candidate we are seeking will work within our Formulation and DP Development team to participate in formulation and DP development for phase appropriate liquid and lyophilized formulations for intermediates, drug substance and drug products. The successful candidate will participate in activities in technology transfer to CMO's. The position is expected to design, execute, document formulation, stability and in-use/compatibility studies to support the final formulation, clinical administration and manufacturing processes. The position will utilize/implement fit-for-purpose analytical methods for biophysical characterization, formulation and process development and stability testing. This position is expected to communicate experimental data both verbally at group, department and cross functional meetings and through written documents and reports that may be included in regulatory filings.

Qualifications:

• BS/MS(12+ years)orPhD(7+ years)of experiencein scientific discipline (Pharmaceutical Sciences, Chemistry, Chemical Engineering, Biomedical Engineering, or related discipline)anddemonstrated scientific creativity and contributions
• Solid technical skills and experience in pre-formulation screening studies,biophysical/biochemical characterization of proteins, analytical method development and protein/antibody/ADC product developmentisessential
• Practical experience with design and execution of in-use stability studies for biologics and compatibility with administration components
• Demonstrated ability to design experiments and routinely generate new ideas and original research. High level of scientific initiative and independence. Highly autonomous requiring minimal supervision from manager.
• Analytical instrumentation such as chromatographic (HPLC, UPLC, column chromatography), visible and subvisible particle analysis, capillary electrophoresis and/or biophysical techniques (UV-vis, MALS/DLS, DSC, CD, FTIR, AUC, Fluorescence spectroscopy) for protein characterization are highly desirable.
• Able to cooperate effectively with cross functional teams, such as up and down stream process development, manufacturing and quality.Ability to quickly adapt to changes in project direction.
• Working knowledge of cGMP and relevant drug product development guidelines and regulations
• Flexibility to work on multiple projects between departments in a fast-paced environment is essential.
• Excellent oral and written communication skills and being detailed oriented are important attributes.

Sound exciting? Apply today and join our team!

Sutro Biopharma, Inc. encourages all colleagues to be fully vaccinated for COVID-19 prior to the first date of employment.

As an equal opportunity employer, we believe in fostering a culture that is inclusive and values diversity in background and opinions. Sutro Biopharma hires extraordinary individuals into every position in the company and is committed to the diversity of our team. Our company progresses without regardofrace, ethnicity, gender, sexual orientation, religious belief, age, disability or citizenship status. We are dedicated to creating a safe environment where our employees can grow and succeed together.

We look forward to hearing from candidates who are interested in exploring opportunities with Sutro! Our People & Culture team/hiring managers are unable to respond and do not accept solicitations from third-party agencies.

The anticipated salary range for fully qualified candidates applying for this role at Sutro Biopharma's California based locations willbe$155,000 - $168,000(not including bonus, equity, and benefits). The final salary offered will be dependent on several factors that include and are not limited to relevant previous experience, job responsibilities and duration of experience, the type and length of experience within the industry and education.

About Sutro Biopharma

Sutro Biopharma, Inc. is advancing a next-generation antibody-drug conjugate (ADC) platform designed to deliver single- and dual-payload ADCs that enable meaningful breakthroughs for patients with cancer. By fully optimizing the antibody, linker, and payload, Sutro's cell-free platform produces ADCs that are engineered to improve drug exposure, reduce side effects, and expand the range of treatable tumor types. With unique capabilities in dual-payload ADCs, Sutro aims to overcome treatment resistance and redefine what's possible in cancer therapy. The Company's pipeline of single- and dual-payload ADCs targets large oncology markets with limited treatment options and significant need for improved therapies.

Employment Type: Regular Full-Time