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Fluorescence Spectroscopy Jobs in Colorado (NOW HIRING)

Scientist I

Louisville, CO · On-site

$84K - $115K/yr

Expertise in mass spectrometry techniques including intact mass and subunit analysis, reduced and ... icIEF), UV/Fluorescence, compendial methods, and biophysical characterization techniques on ...

Scientist I

Louisville, CO · On-site

$84K - $115K/yr

Expertise in mass spectrometry techniques including intact mass and subunit analysis, reduced and ... icIEF), UV/Fluorescence, compendial methods, and biophysical characterization techniques on ...

Fluorescence Spectroscopy information

See Colorado salary details

$38.9K

$100.4K

$181.4K

How much do fluorescence spectroscopy jobs pay per year?

As of Aug 7, 2026, the average yearly pay for fluorescence spectroscopy in Colorado is $100,382.00, according to ZipRecruiter salary data. Most workers in this role earn between $80,400.00 and $115,700.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a fluorescence spectroscopy specialist?

To excel as a Fluorescence Spectroscopy Specialist, you need a solid background in chemistry or physics, experience with laboratory protocols, and often a relevant degree such as a BSc or MSc. Familiarity with spectroscopic instrumentation, data analysis software (like Origin or MATLAB), and possibly certifications in laboratory safety are commonly required. Attention to detail, problem-solving skills, and effective communication are essential soft skills for interpreting results and collaborating with research teams. These competencies ensure accurate experimental outcomes, reliable data interpretation, and successful project execution in research or industrial environments.

What is the difference between Fluorescence Spectroscopy vs Spectroscopy Technician?

AspectFluorescence SpectroscopySpectroscopy Technician
CredentialsTypically requires a degree in chemistry, biochemistry, or physics; certifications varyAssociate or bachelor's degree in chemistry, physics, or related field; certifications may be preferred
Work EnvironmentLaboratories, research facilities, or industrial settingsLaboratories, manufacturing plants, or quality control labs
Industry UsageResearch, pharmaceuticals, environmental testing, materials scienceManufacturing, quality assurance, environmental monitoring

Fluorescence Spectroscopy involves using specialized instruments to analyze the fluorescent properties of samples, often requiring advanced knowledge of optics and chemistry. In contrast, a Spectroscopy Technician performs routine maintenance, calibration, and data collection across various spectroscopic methods. Both roles are essential in laboratory settings but differ in complexity and focus.

What are some common challenges faced by professionals working in fluorescence spectroscopy, and how can they be addressed?

Professionals in fluorescence spectroscopy often encounter challenges such as sample photobleaching, background fluorescence interference, and the need for precise instrument calibration. Addressing these issues typically involves optimizing sample preparation protocols, selecting appropriate fluorophores, and utilizing advanced data analysis software. Collaboration with chemists, biologists, and instrumentation specialists is also key to troubleshooting experimental hurdles and ensuring reliable results.

What is fluorescence spectroscopy?

Fluorescence spectroscopy is an analytical technique used to study the properties of substances by measuring their fluorescence, which is the emission of light by a substance that has absorbed light or other electromagnetic radiation. This technique is commonly used in chemistry, biology, and materials science to analyze the composition and behavior of molecules, detect trace amounts of substances, and study molecular interactions. Fluorescence spectroscopy is valued for its high sensitivity, specificity, and ability to provide information about molecular environments and dynamics.
Infographic showing various Fluorescence Spectroscopy job openings in Colorado as of August 2026, with employment types broken down into 52% Full Time, 43% Part Time, 1% Temporary, and 4% Contract. Highlights an 57% Physical, and 43% Remote job distribution, with an average salary of $100,382 per year, or $48.3 per hour.

$84K - $115K/yr

Full-time

Posted 17 days ago


KBI Biopharma rating

6.5

Company rating: 6.5 out of 10

Based on 6 frontline employees who took The Breakroom Quiz


Job description

KBI Biopharma is seeking a highly skilled and motivated Analytical Scientist to join our Analytical and Formulation Sciences (AFS) team in Louisville, CO. This role is ideal for a scientist with deep expertise in protein analytics, ideally with a background in mass spectrometry and protein structural characterization. You will serve as a subject matter expert (SME), driving innovation and excellence in analytical testing to support client programs from early development through late-phase and commercialization for biotherapeutics.
Position Responsibilities:

  • Demonstrates expertise in the execution and interpretation of experiments that contribute to project goals.
  • Expertise in mass spectrometry techniques including intact mass and subunit analysis, reduced and non-reduced peptide mapping, and PTM and sequence variant analysis.
  • Significant experience is desired in optimizing multiple chromatographic modalities relevant to mass spectrometry, including SEC, RP, HILIC, and CEX.
  • Familiarity with Agilent, Waters, and Thermo LC-MS systems.
  • Occasional recourse to non LC-MS methods including capillary electrophoresis (SDS-CGE and icIEF), UV/Fluorescence, compendial methods, and biophysical characterization techniques on proteins (CD, FTIR, DLS, SEC-MALS, calorimetry).
  • Design and strategically execute analytical experiments in support of biotherapeutics development, particularly qualification/validation and stability studies.
  • Generate high-quality documentation suitable for publication and regulatory review, including technical documents and analytical test methods.
  • Act as SME on client programs, providing technical guidance and representing KBI in client interactions.
  • Collaborate cross-functionally with rapid analytics, process development, bioassay, and program management teams.
  • Mentor and train junior scientists and associates.
  • Perform peer review of data and reports related to method development, qualification, and validation, as well as characterization and stability study reports.
  • Manage timelines and resources to meet project milestones and proactively advise leadership on program status and technical challenges.

Minimum Requirements:

  • Ph.D. in Biochemistry, Analytical Chemistry, or a related field with 0-3 years experience; M.S. with 3-7 years experience; B.S. degree with >7 years experience.
  • Adaptability to changing priorities and business needs.
  • Adherence to statutory and company safety requirements.
  • Strong understanding of protein structure and stability and degradation pathways leading to PTMs.
  • Excellent communication skills and ability to present complex data to diverse audiences.
  • Proficiency in scientific software and data analysis tools (e.g. Excel, Prism).
  • Ability to work independently and collaboratively in a fast-paced environment.

Salary: $84,000-$115,000

KBI Biopharma, Inc. is an EEO/AA employer and actively seeks to diversify its work force. Therefore, all qualified applicants, regardless of race, color, national origin, religion, gender, gender identity, sexual orientation, age, disability or veteran status, are strongly encouraged to apply.

I understand that neither the completion of this application nor any other part of my consideration for employment establishes any obligation for KBI Biopharma, Inc. to hire me. If I am hired, I understand that either KBI Biopharma, Inc. or I can terminate my employment at any time and for any reason, with or without cause and without prior notice. I understand that no representative of KBI Biopharma, Inc. has the authority to make any assurance to the contrary.

I attest with my signature below that I have given to KBI Biopharma, Inc. true and complete information on this application. No requested information has been concealed. I authorize KBI Biopharma, Inc. to contact references provided for employment reference checks. If any information I have provided is untrue, or if I have concealed material information, I understand that this will constitute cause for the denial of employment or immediate dismissal.

KBI Biopharma, Inc. is an EEO/AA employer and actively seeks to diversify its work force. Therefore, all qualified applicants, regardless of race, color, national origin, religion, gender, gender identity, sexual orientation, age, disability or veteran status, are strongly encouraged to apply.

I understand that neither the completion of this application nor any other part of my consideration for employment establishes any obligation for KBI Biopharma, Inc. to hire me. If I am hired, I understand that either KBI Biopharma, Inc. or I can terminate my employment at any time and for any reason, with or without cause and without prior notice. I understand that no representative of KBI Biopharma, Inc. has the authority to make any assurance to the contrary.

I attest with my signature below that I have given to KBI Biopharma, Inc. true and complete information on this application. No requested information has been concealed. I authorize KBI Biopharma, Inc. to contact references provided for employment reference checks. If any information I have provided is untrue, or if I have concealed material information, I understand that this will constitute cause for the denial of employment or immediate dismissal.


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