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Fluorescence Microscopy Jobs in California (NOW HIRING)

Sr. Mechanical Engineer

San Jose, CA · On-site

$86K - $153K/yr

Divisions within BNANO include Bruker AXS, Bruker Nano Analytics, Bruker Nano Surfaces and Metrology, Fluorescence Microscopy, and Canopy. We are seeking a talented Optical-Mechanical Engineer to ...

Sr. Mechanical Engineer

San Jose, CA · On-site

$86K - $153K/yr

Divisions within BNANO include Bruker AXS, Bruker Nano Analytics, Bruker Nano Surfaces and Metrology, Fluorescence Microscopy, and Canopy. We are seeking a talented Optical-Mechanical Engineer to ...

Sr. Mechanical Engineer

San Jose, CA · On-site

$100 - $125/hr

Divisions within BNANO include Bruker AXS, Bruker Nano Analytics, Bruker Nano Surfaces and Metrology, Fluorescence Microscopy, and Canopy. We are seeking a talented Optical-Mechanical Engineer to ...

Sr. Mechanical Engineer

San Jose, CA · On-site

$86K - $153K/yr

Divisions within BNANO include Bruker AXS, Bruker Nano Analytics, Bruker Nano Surfaces and Metrology, Fluorescence Microscopy, and Canopy. We are seeking a talented Optical-Mechanical Engineer to ...

Divisions within BNANO include Bruker AXS, Bruker Nano Analytics, Bruker Nano Surfaces and Metrology, Fluorescence Microscopy, and Canopy. We are seeking a talented Optical-Mechanical Engineer to ...

Research Associate

San Francisco, CA · On-site

$80 - $100/hr

Experience with standard biochemical or imaging assays (e.g., SDS‑PAGE, fluorescence microscopy, enzymatic assays). * Familiarity with rodent models or in vivo experimental workflows. If you're ...

Sr. Mechanical Engineer

San Jose, CA · On-site

$86K - $153K/yr

Divisions within BNANO include Bruker AXS, Bruker Nano Analytics, Bruker Nano Surfaces and Metrology, Fluorescence Microscopy, and Canopy. We are seeking a talented Optical-Mechanical Engineer to ...

Research Associate

San Francisco, CA · On-site

$95K - $120K/yr

Experience with standard biochemical or imaging assays (e.g., SDS-PAGE, fluorescence microscopy, enzymatic assays). * Familiarity with rodent models or in vivo experimental workflows. If you're ...

Familiarity with imaging-based cell assays (e.g., high-content imaging, fluorescence microscopy) * Experience with cell-free protein expression or specialized enzyme workflows * Comfort working with ...

Familiarity with imaging‑based cell assays (e.g., high‑content imaging, fluorescence microscopy) * Experience with cell‑free protein expression or specialized enzyme workflows * Comfort working ...

Applications Scientist

San Jose, CA · On-site

$70K - $125K/yr

Divisions within BNANO include Bruker AXS, Bruker Nano Analytics, Bruker Nano Surfaces and Metrology, Fluorescence Microscopy, and Canopy. Bruker's Semiconductor (BSEMI) Division is the leader in ...

Divisions within BNANO include Bruker AXS, Bruker Nano Analytics, Bruker Nano Surfaces and Metrology, Fluorescence Microscopy, and Canopy. Bruker's Semiconductor (BSEMI) Division is the leader in ...

Applications Scientist

San Jose, CA · On-site

$70K - $125K/yr

Divisions within BNANO include Bruker AXS, Bruker Nano Analytics, Bruker Nano Surfaces and Metrology, Fluorescence Microscopy, and Canopy. Bruker's Semiconductor (BSEMI) Division is the leader in ...

Applications Scientist

San Jose, CA · On-site

$79K - $125K/yr

Divisions within BNANO include Bruker AXS, Bruker Nano Analytics, Bruker Nano Surfaces and Metrology, Fluorescence Microscopy, and Canopy. Bruker's Semiconductor (BSEMI) Division is the leader in ...

Applications Scientist

San Jose, CA · On-site

$100 - $125/hr

Divisions within BNANO include Bruker AXS, Bruker Nano Analytics, Bruker Nano Surfaces and Metrology, Fluorescence Microscopy, and Canopy. Bruker's Semiconductor (BSEMI) Division is the leader in ...

Divisions within BNANO include Bruker AXS, Bruker Nano Analytics, Bruker Nano Surfaces and Metrology, Fluorescence Microscopy, and Canopy. Bruker's Semiconductor (BSEMI) Division is the leader in ...

Showing results 41-60

Fluorescence Microscopy information

See California salary details

$29.9K

$103K

$175.3K

How much do fluorescence microscopy jobs pay per year?

As of Sep 8, 2026, the average yearly pay for fluorescence microscopy in California is $102,961.00, according to ZipRecruiter salary data. Most workers in this role earn between $54,836.00 and $143,457.00 per year, depending on experience, location, and employer.

What is fluorescence microscopy?

A Fluorescence Microscopy job involves using specialized microscopes and fluorescent dyes to study biological samples at a microscopic level. Professionals in this field work in research labs, hospitals, or biotech companies, imaging cells, tissues, or molecular structures. Responsibilities may include sample preparation, image analysis, and troubleshooting microscope equipment. This role is crucial in biomedical research, diagnostics, and drug development. Strong expertise in microscopy techniques and data interpretation is typically required.

What types of samples or experiments will I typically work with in fluorescence microscopy?

In a Fluorescence Microscopy role, you will often prepare and analyze biological samples such as cells, tissues, or small organisms, applying fluorescent labeling techniques to visualize specific structures or molecules. Your daily work may include designing experiments, optimizing imaging protocols, and interpreting data for research or diagnostics. Collaboration with other scientists or lab technicians is common, as projects can be multidisciplinary and require input from different areas of expertise. This hands-on, research-driven environment offers opportunities to develop new imaging techniques and contribute to scientific discoveries.

What are the most commonly searched types of Fluorescence Microscopy jobs in California?

The most popular types of Fluorescence Microscopy jobs in California are:

What are popular job titles related to Fluorescence Microscopy jobs in California?

For Fluorescence Microscopy jobs in California, the most frequently searched job titles are:

What job categories do people searching Fluorescence Microscopy jobs in California look for?

The top searched job categories for Fluorescence Microscopy jobs in California are:

What cities in California are hiring for Fluorescence Microscopy jobs?

Cities in California with the most Fluorescence Microscopy job openings:

Infographic showing various Fluorescence Microscopy job openings in California as of September 2026, with employment types broken down into 66% Full Time, 28% Part Time, and 6% Contract. Highlights an 92% In-person, 2% Hybrid, and 6% Remote job distribution, with an average salary of $102,961 per year, or $49.5 per hour.

Sr. Optical-Mechanical Engineer

Bruker Corporation

San Jose, CA • On-site

$150 - $200/hr

Other

Medical, Dental, Life, Retirement, PTO

Re-posted 24 days ago


Key responsibilities

  • Design precision optical-mechanical components, modules, and subsystems for microscopy illumination and imaging.

  • Develop and test prototypes to validate design concepts and ensure robustness under varying environmental conditions.

  • Collaborate with cross-functional teams to integrate optical-mechanical systems into larger systems or products.


Bruker rating

7.4

Company rating: 7.4 out of 10

Based on 17 frontline employees who took The Breakroom Quiz


Job description

Overview

As one of the world’s leading analytical instrumentation companies, Bruker covers a broad spectrum of advanced solutions in all fields of research and development. All our systems and instruments are designed to improve safety of products, to accelerate time-to-market, and to support industries in successfully enhancing quality of life. We have been driving innovation in analytical instrumentation for over 60 years now. Today, more than 11,000 employees distributed across 90 locations around the world continue to delight our customers with innovative solutions.

Bruker Nano, one of Bruker’s four operating segments, provides customers in academic and governmental institutions, life science, materials, and applied industries with the tools to determine the characteristics of matter and visualize the structure of molecules. Divisions within BNANO include Bruker AXS, Bruker Nano Analytics, Bruker Nano Surfaces and Metrology, Fluorescence Microscopy, and Canopy.

We are seeking a talented Optical-Mechanical Engineer to join our dynamic team. As an Optical-Mechanical Engineer, you will play a pivotal role in designing, developing, and optimizing Optical-Mechanical systems and components. You will collaborate closely with cross-functional teams to innovate and deliver high-performance solutions that meet our customers' needs and exceed industry standards.

Responsibilities
  • Design precision components, modules, and subsystems focused on optic mounting, actuating, and alignment for microscopy illumination and imaging.
  • Designs need to account for stability and reproducibility, mitigating thermal and vibration effects, material properties of optical elements and machine parts, and proper adhesives and lubricants under varying environmental conditions for robustness.
  • Design mechanical components and assemblies by encompassing mechanical engineering principles and best practices.
  • Design for manufacturability and serviceability.
  • Perform stack up and tolerance analysis to ensure proper fit and function of assemblies under extreme operating conditions.
  • Develop and test prototypes to validate design concepts and project requirements.
  • Collaborate with optical engineers, mechanical engineers, electrical engineers, systems engineers, software engineers, and manufacturing teams to integrate optical-mechanical systems into larger systems or products.
  • Participate in and lead design reviews to obtain peer-oriented design assessments throughout design processes.
  • Generate detailed component and assembly drawings, BOMs, ECOs, and build/inspection/test procedures.
Qualifications
  • Bachelor's degree in Mechanical Engineering, Optics, Physics, or a related field with 5 years experience, Master's with 2 years experience or PhD preferred.
  • Proven experience in designing and developing optical-mechanical systems and components.
  • Proficiency in converting Zemax software optical designs into mechanical design.
  • Proficiency in designing in SolidWorks. Proficiency in designing in SolidEdge a plus.
  • Proficiency in geometric dimensioning and tolerancing, and tolerance stack up analysis.
  • Hands-on experience with optical measurement equipment and testing methods.
  • Strong analytical and problem-solving skills with a meticulous attention to detail.
  • Ability to work effectively in cross-functional teams and manage multiple projects simultaneously.
  • Excellent communication skills, both verbal and written.
  • Experience with regulatory requirements and standards (e.g., ISO, Semi, CE) preferred.

At Bruker, base salary is part of our total compensation. The estimated base salary range for this full-time position is between $122,850 and $182,000 and provides an opportunity to progress as you grow and develop within a role. The base salary for the role will depend on a several job-related factors, including, but not limited to education, training, experience, the geographic location of the successful candidate, skills, competencies, job-related knowledge and travel requirements for this position. Full-time employees may also be eligible for a performance-related incentive in addition to a full range of benefits including 401(k) with company match, an employee stock purchase plan, medical and dental plans, life insurance, short-term and long-term disability insurance, employee assistance program and paid time off including vacation, sick time and holidays, and more.

Bruker is an equal-opportunity employer. We evaluate qualified applicants without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, veteran status, and other legally protected characteristics.

Certain positions at Bruker require compliance with export control laws and as a result, all interviewed candidates for all positions will be screened pre-interview to determine their eligibility in light of export control restrictions.

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