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Fluorescence Microscopy Jobs in California (NOW HIRING)

Prepare cleared tissue for light sheet fluorescence microscopy and volumetric 3D imaging * Operate and maintain automated sectioning and tissue processing systems * Prepare and process samples for ...

Prepare cleared tissue for light sheet fluorescence microscopy and volumetric 3D imaging * Operate and maintain automated sectioning and tissue processing systems * Prepare and process samples for ...

Postdoctoral Researcher - Zhou Lab

Novato, CA · On-site

$73K - $81K/yr

  • Medical

  • Dental

  • Vision

  • Retirement

  • PTO

Experience with budding yeast or mammalian cell culture, protein purification, ribosome profiling, quantitative proteomics, fluorescence microscopy, or single-particle cryo-EM. * Interest in learning ...

Senior Scientist, Surface Chemistry

Fremont, CA

$120K - $140K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Hands-on metrology experience, including AFM, Ellipsometry, XPS, FTIR, SEM, fluorescence microscopy; additional techniques are a plus * Proven SOP authoring and release and documentation discipline ...

Sr. Optical-Mechanical Engineer

San Jose, CA

$122K - $182K/yr

  • Medical

  • Dental

  • Life

  • Retirement

  • PTO

Divisions within BNANO include Bruker AXS, Bruker Nano Analytics, Bruker Nano Surfaces and Metrology, Fluorescence Microscopy, and Canopy. We are seeking a talented Optical-Mechanical Engineer to ...

Sr. Optical-Mechanical Engineer

San Jose, CA · On-site

$136K - $182K/yr

  • Medical

  • Dental

  • Life

  • Retirement

  • PTO

Divisions within BNANO include Bruker AXS, Bruker Nano Analytics, Bruker Nano Surfaces and Metrology, Fluorescence Microscopy, and Canopy. We are seeking a talented Optical-Mechanical Engineer to ...

Title Sr. Optical-Mechanical Engineer

San Jose, CA · On-site

$122K - $182K/yr

  • Medical

  • Dental

  • Life

  • Retirement

  • PTO

Divisions within BNANO include Bruker AXS, Bruker Nano Analytics, Bruker Nano Surfaces and Metrology, Fluorescence Microscopy, and Canopy. We are seeking a talented Optical-Mechanical Engineer to ...

Research Associate - Protein

San Francisco, CA · On-site

  • Medical

  • Dental

  • Retirement

  • PTO

Familiarity with imaging-based cell assays (e.g., high-content imaging, fluorescence microscopy) * Experience with cell-free protein expression or specialized enzyme workflows * Comfort working with ...

Showing results 21-40

Fluorescence Microscopy information

See California salary details

$29.9K

$103K

$175.3K

How much do fluorescence microscopy jobs pay per year?

As of Aug 18, 2026, the average yearly pay for fluorescence microscopy in California is $102,961.00, according to ZipRecruiter salary data. Most workers in this role earn between $54,836.00 and $143,457.00 per year, depending on experience, location, and employer.

What is fluorescence microscopy?

A Fluorescence Microscopy job involves using specialized microscopes and fluorescent dyes to study biological samples at a microscopic level. Professionals in this field work in research labs, hospitals, or biotech companies, imaging cells, tissues, or molecular structures. Responsibilities may include sample preparation, image analysis, and troubleshooting microscope equipment. This role is crucial in biomedical research, diagnostics, and drug development. Strong expertise in microscopy techniques and data interpretation is typically required.

What types of samples or experiments will I typically work with in fluorescence microscopy?

In a Fluorescence Microscopy role, you will often prepare and analyze biological samples such as cells, tissues, or small organisms, applying fluorescent labeling techniques to visualize specific structures or molecules. Your daily work may include designing experiments, optimizing imaging protocols, and interpreting data for research or diagnostics. Collaboration with other scientists or lab technicians is common, as projects can be multidisciplinary and require input from different areas of expertise. This hands-on, research-driven environment offers opportunities to develop new imaging techniques and contribute to scientific discoveries.

What are the most commonly searched types of Fluorescence Microscopy jobs in California?

The most popular types of Fluorescence Microscopy jobs in California are:

What job categories do people searching Fluorescence Microscopy jobs in California look for?

The top searched job categories for Fluorescence Microscopy jobs in California are:

What cities in California are hiring for Fluorescence Microscopy jobs?

Cities in California with the most Fluorescence Microscopy job openings:

Infographic showing various Fluorescence Microscopy job openings in California as of August 2026, with employment types broken down into 50% Full Time, and 50% Contract. Highlights an 100% In-person job distribution, with an average salary of $102,961 per year, or $49.5 per hour.

Histotechnologist

Nudge Inc.

San Francisco, CA • On-site

Other

Re-posted 12 hours ago


Job description

Histotechnologist

At Nudge, our mission is to develop the best technology for interfacing with the brain to improve people's lives. We're starting with an approach that we believe can help the most people the fastest, and also allow us to learn as much about the brain as possible: developing a non-invasive, ultrasound-based device that can stimulate and image the brain at high resolution and depth. This is a vertically integrated effort building cutting-edge hardware, software, and research capabilities to create products that can benefit millions — and eventually billions — of people.

To succeed, we need to assemble world-class teams across everything we do. We hire people who are exceptional at their craft, believe hard things are worth doing, and execute relentlessly — people who expect the highest levels of both rigor and integrity from each other.

About the Role

We're looking for a histotechnologist to own and execute histology workflows at Nudge, focused primarily on mouse and rat brain tissue. You'll be responsible for building the full histology pipeline: perfusion, prosection, embedding, sectioning, staining, and imaging — across both traditional and cutting-edge techniques, to understand the mechanisms of ultrasonic neuromodulation.

As a histotechnologist at Nudge, you will:

  • Perform routine and advanced histological processing of rodent brain tissue, including perfusion, prosection, fixation, embedding (paraffin and OCT), and sectioning via microtome, cryostat, and vibratome
  • Execute standard histological stains (H&E, special stains) and immunohistochemistry using both manual and automated staining platforms
  • Operate and optimize tissue clearing platforms (electrophoretic, solvent-based) for whole-brain and thick-section imaging
  • Prepare cleared tissue for light sheet fluorescence microscopy and volumetric 3D imaging
  • Operate and maintain automated sectioning and tissue processing systems
  • Prepare and process samples for spatial omics platforms, including multiplexed protein imaging and spatial transcriptomics, with both RNA- and protein-based tagging approaches
  • Develop, optimize, and document SOPs for histological workflows, ensuring reproducibility and quality
  • Collaborate with research scientists to adapt tissue processing and staining strategies to specific experimental questions
About You

We are looking for histotechnologists with at least 3 years of industry experience. Regardless of career level, you should have:

  • Hands-on experience in histotechnology, with significant time spent processing rodent brain tissue
  • Proficiency across core histological techniques: microtomy (paraffin, cryo, vibratome), tissue embedding, H&E staining, and immunohistochemistry
  • Experience with at least one tissue clearing method and associated imaging modalities (light sheet microscopy)
  • Familiarity with automated staining and sectioning platforms
  • HT(ASCP) certification or equivalent training; Bachelor's degree in biology, neuroscience, or a related field preferred
  • High integrity and strong professional judgment