... single cell genomics, spatial transcriptomics, or multiomics platforms; experience building or ... scaling these capabilities in an organizational context is strongly preferred Strong publication ...
... single cell genomics, spatial transcriptomics, or multiomics platforms; experience building or ... scaling these capabilities in an organizational context is strongly preferred Strong publication ...
Principal Scientist, Translational Oncology - Single Cell and Spatial Genomics, Solid Tumors
San Francisco, CA · On-site
$171K - $214K/yr
... with single cell genomics, spatial transcriptomics, or multiomics platforms; experience building or scaling these capabilities in an organizational context is strongly preferred • Strong ...
Principal Scientist, Translational Oncology - Single Cell and Spatial Genomics, Solid Tumors
San Francisco, CA · On-site
$171K - $214K/yr
... with single cell genomics, spatial transcriptomics, or multiomics platforms; experience building or scaling these capabilities in an organizational context is strongly preferred • Strong ...
A central focus of this role is to drive and execute on Nkarta's strategy for single-cell and spatial transcriptomics, leveraging scRNA-seq, spatial, and functional genomics approaches to drive ...
A central focus of this role is to drive and execute on Nkarta's strategy for single-cell and spatial transcriptomics, leveraging scRNA-seq, spatial, and functional genomics approaches to drive ...
Biomedical Specialist - Genomics Core
West Hollywood, CA · On-site
$78K - $121K/yr
We specialize in single cell omics and spatial transcriptomics via the 10x Genomics, Parse Biosciences, Mission Bio, and NanoString platforms. Our R&D team offers sample preparation for single cell ...
Biomedical Specialist - Genomics Core
West Hollywood, CA · On-site
$78K - $121K/yr
We specialize in single cell omics and spatial transcriptomics via the 10x Genomics, Parse Biosciences, Mission Bio, and NanoString platforms. Our R&D team offers sample preparation for single cell ...
Scientist 3 - Translational Medicine - OMNI - Inflammatory Bowel Disease
South San Francisco, CA · On-site
$100K - $186K/yr
Experience using computational tools to directly analyze high-dimensional single-cell, spatial transcriptomics, or proteomics data beyond standard bench generation. * Demonstrated track record of ...
Scientist 3 - Translational Medicine - OMNI - Inflammatory Bowel Disease
South San Francisco, CA · On-site
$100K - $186K/yr
Experience using computational tools to directly analyze high-dimensional single-cell, spatial transcriptomics, or proteomics data beyond standard bench generation. * Demonstrated track record of ...
Deep expertise in single-cell and spatial transcriptomics analysis, including scRNA-seq and related high-dimensional omics datasets * Strong experience analyzing functional genomics and ...
Deep expertise in single-cell and spatial transcriptomics analysis, including scRNA-seq and related high-dimensional omics datasets * Strong experience analyzing functional genomics and ...
Experience using computational tools to directly analyze high-dimensional single-cell, spatial transcriptomics, or proteomics data beyond standard bench generation. * Demonstrated track record of ...
Experience using computational tools to directly analyze high-dimensional single-cell, spatial transcriptomics, or proteomics data beyond standard bench generation. * Demonstrated track record of ...
Biomedical Specialist - Genomics Core
$21.75 - $29.75/hr
We specialize in single cell omics and spatial transcriptomics via the 10x Genomics, Parse Biosciences, Mission Bio, and NanoString platforms. Our R&D team offers sample preparation for single cell ...
Biomedical Specialist - Genomics Core
$21.75 - $29.75/hr
We specialize in single cell omics and spatial transcriptomics via the 10x Genomics, Parse Biosciences, Mission Bio, and NanoString platforms. Our R&D team offers sample preparation for single cell ...
Biomedical Technician - Genomics Core
West Hollywood, CA · On-site
$28.50 - $37.75/hr
This includes familiarity with techniques such as single-cell RNA sequencing (scRNA-seq), spatial transcriptomics, multiplex imaging, and other high-dimensional molecular profiling platforms. A ...
Biomedical Technician - Genomics Core
West Hollywood, CA · On-site
$28.50 - $37.75/hr
This includes familiarity with techniques such as single-cell RNA sequencing (scRNA-seq), spatial transcriptomics, multiplex imaging, and other high-dimensional molecular profiling platforms. A ...
Biomedical Technician - Genomics Core
West Hollywood, CA · On-site
$31.08 - $48.17/hr
This includes familiarity with techniques such as single-cell RNA sequencing (scRNA-seq), spatial transcriptomics, multiplex imaging, and other high-dimensional molecular profiling platforms. A ...
Biomedical Technician - Genomics Core
West Hollywood, CA · On-site
$31.08 - $48.17/hr
This includes familiarity with techniques such as single-cell RNA sequencing (scRNA-seq), spatial transcriptomics, multiplex imaging, and other high-dimensional molecular profiling platforms. A ...
Senior Scientist, Bioinformatics
San Diego, CA · On-site
$140K - $155K/yr
Design, implement, and maintain scalable, reproducible pipelines for single-cell RNA-seq, spatial transcriptomics, and integrative multiomics data analysis, from raw data through biological ...
Senior Scientist, Bioinformatics
San Diego, CA · On-site
$140K - $155K/yr
Design, implement, and maintain scalable, reproducible pipelines for single-cell RNA-seq, spatial transcriptomics, and integrative multiomics data analysis, from raw data through biological ...
Senior Scientist, Bioinformatics
San Diego, CA · On-site
$140K - $155K/yr
Design, implement, and maintain scalable, reproducible pipelines for single-cell RNA-seq, spatial transcriptomics, and integrative multiomics data analysis, from raw data through biological ...
Quick apply
Senior Scientist, Bioinformatics
San Diego, CA · On-site
$140K - $155K/yr
Design, implement, and maintain scalable, reproducible pipelines for single-cell RNA-seq, spatial transcriptomics, and integrative multiomics data analysis, from raw data through biological ...
Senior Scientist, Bioinformatics
$140K - $155K/yr
Design, implement, and maintain scalable, reproducible pipelines for single-cell RNA-seq, spatial transcriptomics, and integrative multiomics data analysis, from raw data through biological ...
Senior Scientist, Bioinformatics
$140K - $155K/yr
Design, implement, and maintain scalable, reproducible pipelines for single-cell RNA-seq, spatial transcriptomics, and integrative multiomics data analysis, from raw data through biological ...
Computational Biologist
Palo Alto, CA · On-site
Stay current with advances in transcriptomics, single-cell methods, and computational biology ... Familiarity with spatial transcriptomics or multimodal data integration approaches. * Experience ...
Computational Biologist
Palo Alto, CA · On-site
Stay current with advances in transcriptomics, single-cell methods, and computational biology ... Familiarity with spatial transcriptomics or multimodal data integration approaches. * Experience ...
Postdoctoral Scientist - Ajami Lab - Department of Neurology
West Hollywood, CA · On-site
$62K - $93K/yr
Using human postmortem tissues, spatial transcriptomics, spatial proteomics, single-cell genomics, CRISPR genome engineering, and human iPSC-derived microglia and motor neuron models, our goal is to ...
Postdoctoral Scientist - Ajami Lab - Department of Neurology
West Hollywood, CA · On-site
$62K - $93K/yr
Using human postmortem tissues, spatial transcriptomics, spatial proteomics, single-cell genomics, CRISPR genome engineering, and human iPSC-derived microglia and motor neuron models, our goal is to ...
Using human postmortem tissues, spatial transcriptomics, spatial proteomics, single-cell genomics, CRISPR genome engineering, and human iPSC-derived microglia and motor neuron models, our goal is to ...
Using human postmortem tissues, spatial transcriptomics, spatial proteomics, single-cell genomics, CRISPR genome engineering, and human iPSC-derived microglia and motor neuron models, our goal is to ...
... single cell ATACseq and spatial transcriptomics • General multiomics expertise: genomics ... transcriptomics, epigenomics, chromatin dynamics • Experience building intuitive web tools for ...
... single cell ATACseq and spatial transcriptomics • General multiomics expertise: genomics ... transcriptomics, epigenomics, chromatin dynamics • Experience building intuitive web tools for ...
Research Scientist
Pasadena, CA · On-site
... edge single-cell and spatial transcriptomics, multiomics and related technologies. The successful applicant will: 1) play a key role in developing and rigorously testing new methods in the above ...
Research Scientist
Pasadena, CA · On-site
... edge single-cell and spatial transcriptomics, multiomics and related technologies. The successful applicant will: 1) play a key role in developing and rigorously testing new methods in the above ...
Senior Bioinformatics Scientist
South San Francisco, CA · On-site
$75 - $85/hr
... single-cell RNAseq and spatial transcriptomics (experience in building NGS pipelines is not required but is a plus). • Basic understanding of disease biology and molecular/cellular mechanisms in ...
Senior Bioinformatics Scientist
South San Francisco, CA · On-site
$75 - $85/hr
... single-cell RNAseq and spatial transcriptomics (experience in building NGS pipelines is not required but is a plus). • Basic understanding of disease biology and molecular/cellular mechanisms in ...
Experience with single-cell sequencing and spatial transcriptomics is also valuable. Histology experience is preferred but is considered more flexible than NGS experience. The candidate should at ...
Experience with single-cell sequencing and spatial transcriptomics is also valuable. Histology experience is preferred but is considered more flexible than NGS experience. The candidate should at ...
Single Cell Spatial Transcriptomics information
What are the key skills and qualifications needed to thrive as a single cell spatial transcriptomics scientist, and why are they important?
To thrive as a Single Cell Spatial Transcriptomics Scientist, you need a strong background in molecular biology, genomics, and bioinformatics, typically supported by an advanced degree (PhD or MSc) in a relevant field. Familiarity with high-throughput sequencing platforms, spatial transcriptomics technologies (like 10x Genomics Visium or NanoString GeoMx), and data analysis tools such as R or Python is essential. Critical thinking, problem-solving, and effective communication are crucial soft skills for interpreting complex data and collaborating in multidisciplinary teams. These skills and qualities are vital for generating reliable insights into cellular function and spatial organization, which drive innovative research and discovery.
What are the typical challenges faced by professionals working in single cell spatial transcriptomics, and how can they be addressed?
Professionals in Single Cell Spatial Transcriptomics often encounter challenges related to handling large, complex data sets and integrating spatial information with single-cell transcriptomic profiles. These tasks demand strong computational skills and close collaboration with bioinformaticians and other researchers. Effective communication within interdisciplinary teams is essential to ensure experimental design aligns with downstream analysis needs. Staying updated with rapidly evolving technologies and best practices also helps professionals overcome technical hurdles and produce reliable, high-impact results.
What is single cell spatial transcriptomics?
Single cell spatial transcriptomics is a cutting-edge technique that allows researchers to analyze gene expression in individual cells while preserving their spatial location within a tissue. This method combines the high-resolution insights of single-cell RNA sequencing with spatial information, enabling scientists to understand how cells interact and organize within their native environments. It is widely used in biomedical research to study tissue architecture, disease mechanisms, and cellular heterogeneity.
What are popular job titles related to Single Cell Spatial Transcriptomics jobs in California? For Single Cell Spatial Transcriptomics jobs in California, the most frequently searched job titles are:
- Qubit
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- Entry Level Clinical Laboratory Scientist
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- Saturday Research Scientist Electrochemistry
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What job categories do people searching Single Cell Spatial Transcriptomics jobs in California look for? The top searched job categories for Single Cell Spatial Transcriptomics jobs in California are:
What cities in California are hiring for Single Cell Spatial Transcriptomics jobs? Cities in California with the most Single Cell Spatial Transcriptomics job openings:
Principal Scientist, Translational Oncology - Single Cell and Spatial Genomics, Solid Tumors
San Francisco, CA
Other
Re-posted 5 days ago
Natera rating
7.6
Based on 37 frontline employees who took The Breakroom Quiz
60th of 120 rated laboratories
Job description
About the Role
We are seeking a Principal Scientist to serve as a translational and strategic leader within our
Oncology research organization. This role sits at the crossroads of reverse translation, biomarker
science, and cutting-edge genomics technology - driving mechanistic insight from the clinic
back into discovery to accelerate and de-risk our oncology pipeline. The ideal candidate brings
deep expertise in cancer biology, a track record of cross-functional leadership in a pharma or
biotech environment, and hands-on experience building and deploying single cell and spatial
omics capabilities.
What You'll Do
Discovery & Translational Research Leadership
Drive discovery and translational projects in collaboration with AI and internal research
teams with a primary focus on integrating scRNA-seq and spatial biology into Natera's
pipeline.
Collaborate with external translational teams on building single-cell and spatial biology
workflows into their early phase clinical studies.
Leverage novel technologies to inform collaborative reverse and forward translation
efforts as well as internal target discovery and validation projects.
Design and execute lab-based research programs that bridge clinical observations with
mechanistic hypotheses, supporting asset progression and CDP expansion
Technology & Capabilities
Lead and contribute to technology area team focused on single cell genomics and spatial
omics, building out multiomics capabilities to support foundational models and RWD
efforts
Partner with internal and external collaborators to establish, optimize, and deploy cutting-
edge platforms for translational applications
Serve as an internal expert and thought leader on emerging genomics technologies
relevant to oncology drug discovery and development
Cross-Functional & Strategic Engagement
Represent translational science on life cycle, RWD, and BioPharma BD teams
Collaborate with Clinical, Biomarker, Discovery, and Regulatory colleagues to shape
clinical trial design and biomarker plans
Build and maintain external scientific partnerships and advisory relationships as
appropriate
People & Team Development
Lead and mentor a team of scientists and contractors, with a strong commitment to career
development and scientific growth
Foster a collaborative, high-performance team culture with clear goals and accountability
Position Requirements
Ph.D. in Cancer Biology, Molecular/Cellular Biology, Immunology, Bioengineering, or a
closely related field
6+ years of experience post-Ph.D. in oncology translational research within biotech or
pharma, including demonstrated growth into senior or principal scientist roles
Deep scientific expertise in at least one of the following: cancer cell biology, tumor
immunology, cell engineering, or neoantigen biology
Hands-on experience with single cell genomics, spatial transcriptomics, or multiomics
platforms; experience building or scaling these capabilities in an organizational context is
strongly preferred
Strong publication and/or patent record reflecting independent scientific contribution
Demonstrated experience leading cross-functional programs and influencing without
authority across Research, Clinical, and Biomarker teams
Prior experience managing and mentoring scientists at multiple career stages
Exceptional scientific communication skills; ability to synthesize complex data and
present compellingly to diverse audiences