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File Jobs in Massachusetts (NOW HIRING)

AIG

State Filings Analyst- Insurance

Boston, MA · On-site

$76K - $90K/yr

State Filings Analyst We are seeking a State Filings Analyst to support regulatory product filings across multiple personal lines product lines. This role is responsible for preparing and submitting ...

inno

Clinical Filed Service Supervisor

Marlborough, MA · On-site

FLSA Classification: Exempt Department: Clinical Management Reports To: Clinical Director Direct Reports: Case Managers RN, LPNs POSITION SUMMARY: The Clinical Field Supervisor RN will collaborate ...

LexisNexis

Compliance Specialist II

Medford, MA · On-site

The Compliance Specialist II will be asked to assist with special filing projects such as initial filings, name changes, terminations and fund reorganizations. The Compliance Specialist II is ...

RELX Group plc

Compliance Specialist II

Medford, MA · On-site

The Compliance Specialist II will be asked to assist with special filing projects such as initial filings, name changes, terminations and fund reorganizations. The Compliance Specialist II is ...

RELX

Compliance Specialist II

Medford, MA

The Compliance Specialist II will be asked to assist with special filing projects such as initial filings, name changes, terminations and fund reorganizations. The Compliance Specialist II is ...

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How much do file jobs pay per hour?

As of Jun 9, 2026, the average hourly pay for file in Massachusetts is $19.37, according to ZipRecruiter salary data. Most workers in this role earn between $17.31 and $20.72 per hour, depending on experience, location, and employer.

What are File clerks?

File clerks are administrative professionals responsible for organizing, managing, and maintaining records and files in an office or organization. They ensure documents are properly filed, retrieved, and maintained in both physical and electronic formats. File clerks may also be responsible for data entry, document scanning, and assisting other staff with locating important records. This role is essential for keeping information accessible, secure, and up to date, which supports the smooth operation of the business.

What is the difference between File vs Data Entry Clerk?

AspectFileData Entry Clerk
Required credentialsMinimal; often high school diplomaHigh school diploma or equivalent; sometimes additional training
Work environmentOffices, archives, digital storage systemsOffices, data centers, remote work
Employer and industry usageBusinesses, government agencies, legal firmsCorporations, healthcare, finance, government
Common search and comparison intentUnderstanding administrative or record-keeping rolesData management and input tasks

File roles typically involve managing physical or digital records, focusing on organizing and maintaining files. Data Entry Clerks primarily input and update data into systems, often requiring more specific typing and software skills. While both roles support record management, File positions are more about organization, whereas Data Entry Clerks focus on data accuracy and entry speed.

What are the key skills and qualifications needed to thrive as a File Clerk, and why are they important?

To thrive as a File Clerk, you need strong organizational skills, attention to detail, and a high school diploma or equivalent. Familiarity with filing systems, office management software, and sometimes document imaging systems is typically required. Reliability, time management, and discretion with confidential information are standout soft skills in this position. These skills ensure that records are accurately maintained, easily accessible, and secure, which supports smooth office operations.

What are the typical responsibilities of a File Clerk in a modern office setting?

A File Clerk is primarily responsible for organizing, maintaining, and retrieving important documents and records, both in physical and electronic formats. In a modern office, this often includes scanning paper files into digital systems, ensuring that records are accurately labeled and stored, and assisting other departments in locating information efficiently. File Clerks may also be involved in implementing data privacy protocols and supporting administrative staff with general office tasks. Attention to detail and strong organizational skills are essential for success in this role.
What are the most commonly searched types of File jobs in Massachusetts? The most popular types of File jobs in Massachusetts are:
File jobs near you
Infographic showing various File job openings in Massachusetts as of June 2026, with employment types broken down into 75% Full Time, 18% Part Time, 3% Temporary, and 4% Contract. Highlights an 89% Physical, 4% Hybrid, and 7% Remote job distribution, with an average salary of $40,291 per year, or $19.4 per hour.
Associate Director, Trial Master File Lead

Associate Director, Trial Master File Lead

Dyne Therapeutics

Waltham, MA

$36.25 - $49.25/hr

Other

Posted 21 hours ago

Job description

Role Summary:

The Associate Director, Trial Master File (TMF) Lead is responsible for developing and driving the global TMF strategy, establishing and maintaining robust governance frameworks, and ensuring end to end oversight of the Trial Master File across the clinical portfolio. This role serves as the enterprise owner of TMF processes, quality standards, and inspection readiness, ensuring that TMF operations meet regulatory requirements, support high quality clinical execution, and operate efficiently at scale. This role partners closely with Clinical Operations, Quality, Regulatory, and external vendors to ensure a unified, proactive approach to TMF health, completeness, and compliance 
Primary Responsibilities Include: 

TMF Strategy & Leadership: 

  • Define and own the company's TMF strategy, including innovation opportunities and continuous improvement initiatives 
  • Lead the development and implementation of scalable TMF operating models, ensuring alignment with clinical development goals 
  • Serve as the internal subject matter expert on TMF best practices, regulations, and inspection trends 
  • Represent TMF leadership in cross functional forums, governance committees, and senior level operational discussions 

Governance & Process Ownership: 

  • Establish and maintain TMF governance frameworks, including policies, SOPs, work instructions, and quality standards 
  • Oversee TMF lifecycle management-from planning and setup through closeout and archival 
  • Define TMF roles, responsibilities, and RACI structures across internal teams and vendors 
  • Monitor adherence to processes and drive corrective and preventive actions (CAPAs) related to TMF quality issues 
  • Ensure timely collection, review, and management of TMF documents from clinical study teams and external partners  

TMF Oversight & Compliance: 

  • Provide strategic oversight of TMF operations, including ongoing quality reviews, completeness assessments, and key performance indicators (KPIs) 
  • Ensure TMFs across the portfolio remain inspection ready  
  • Lead TMF related preparation for audits, inspections, and regulatory submissions, ensuring all documentation is complete and accurate  
  • Analyze TMF metrics and trends to proactively identify risks, gaps, and improvement opportunities to implement proactively 

Vendor & Technology Management: 

  • Oversee TMF service providers, CRO partners, and technology platforms to ensure alignment with TMF requirements 
  • Partner with IT and business stakeholders to optimize the eTMF system, workflows, and integrations 
  • Ensure vendors adhere to contractual obligations, performance expectations, and quality standards related to TMF 
  • Stay up to date with industry trends and regulatory requirements related to TMF management and documentation practices  

Cross Functional Partnership & Support: 

  • Collaborate with cross-functional study teams to guide TMF planning, milestones, and document management expectations 
  • Provide training, coaching, and strategic direction to internal and external partners on TMF processes and regulatory requirements 
  • Advise leadership on TMF health and organizational readiness for key regulatory events 

Education and Skills Requirements: 

  • Bachelor's degree in life sciences or related field; advanced degree preferred 
  • 8+ years of experience in clinical operations, document management, or related GxP environment, with significant TMF expertise 
  • Strong knowledge of ICHGCP, TMF Reference Model, and global regulatory expectations 
  • Proven experience developing TMF strategy, governance frameworks, or enterprise level processes 
  • Ability to lead cross-functionally without authority Demonstrated leadership in managing TMF operations or oversight at a portfolio level 
  • Experience working with eTMF systems and CRO/vendor oversight 
  • Excellent communication, influencing, and stakeholder management skills 

Apply