1

Fplc Jobs (NOW HIRING)

Perform chromatography of customer samples via FPLC and 2D-PAGE. * Analyze 2D-PAGE data with spot counting software and write reports. * Author SOPs and develop new data analysis tools. * Maintain ...

RESEARCH ASST I (TEMP)

Ann Arbor, MI · On-site

$18.75 - $26/hr

Experience with protein quality control methods, including SDS-PAGE and FPLC. * Strong organizational skills, attention to detail, and the ability to maintain accurate laboratory records. Desired ...

Related technical skill include but not limit to ultrafiltration, TFF, sterile filtration, and FPLC methods. * Performing complicate antibody decorated LNP process and related purification process ...

Manufacturing Scientist

Eugene, OR · On-site

$22 - $24/hr

Use HPLC, FPLC, and gravimetric separation techniques to purify and analyze fluorescent dye-labeled antibodies and other biomolecules. * Analyze and interpret scientific data. * Utilize specialized ...

New

Experience with analytical techniques such as SDS-PAGE, Western blotting, ELISA, HPLC/FPLC, spectrophotometry, and related protein characterization methods. * Familiarity with bioinformatics tools ...

Posted today

Post Doctoral Scholar

Columbus, OH · On-site

$44K - $60K/yr

Responsibilities include expressing recombinant proteins in insect, mammalian, and E. coli cells; purifying proteins using FPLC systems; performing in vitro RNA transcription and labeling; carrying ...

Post Doctoral Scholar

Columbus, OH

$47K - $64K/yr

Responsibilities include expressing recombinant proteins in insect, mammalian, and E. coli cells; purifying proteins using FPLC systems; performing in vitro RNA transcription and labeling; carrying ...

Showing results 41-60

FPLC information

See salary details

$36K

$69.1K

$97.5K

How much do fplc jobs pay per year?

As of Aug 7, 2026, the average yearly pay for fplc in the United States is $69,125.00, according to ZipRecruiter salary data. Most workers in this role earn between $57,000.00 and $78,000.00 per year, depending on experience, location, and employer.

What are some typical challenges faced by FPLC operators and how can they be addressed?

FPLC (Fast Protein Liquid Chromatography) operators frequently encounter challenges such as maintaining consistent sample purity, troubleshooting equipment issues, and optimizing separation protocols for different proteins. To address these, it's important to develop strong problem-solving skills, stay up-to-date with equipment maintenance, and collaborate closely with research scientists to tailor protocols. Regular calibration of instruments and thorough documentation can greatly reduce errors and improve efficiency in the lab.

What are the key skills and qualifications needed to thrive as an FPLC specialist?

To thrive as an FPLC Specialist, you need a solid background in biochemistry, protein purification techniques, and a relevant science degree. Familiarity with chromatography systems such as ÄKTA, and experience with software like Unicorn for method development and data analysis, are typically required. Attention to detail, problem-solving skills, and effective communication are crucial soft skills in this role. These competencies ensure accurate purification processes, reliable results, and efficient collaboration in research or biomanufacturing environments.

What is an FPLC?

FPLC stands for Fast Protein Liquid Chromatography, a technique used to separate and purify proteins from complex mixtures. An FPLC operator is responsible for setting up, running, and maintaining the FPLC system, preparing samples, monitoring purification runs, and analyzing collected fractions. They ensure the equipment operates correctly, troubleshoot issues, and maintain accurate records of purification protocols and results. FPLC operators often work in research labs, biotechnology companies, or pharmaceutical settings where purified proteins are needed for downstream applications.

What is the difference between Fplc vs Fpso?

AspectFplcFpso
Primary FunctionFabricates and installs pipelines and subsea equipment for offshore oil and gasProcesses and stores oil and gas on offshore platforms, then transfers to tankers
Work EnvironmentOffshore and onshore construction sitesOffshore platforms and processing facilities
Required CertificationsOffshore safety and welding certificationsOffshore safety, welding, and process operation certifications

Fplc (Floating Production, Liquefied Natural Gas, and Subsea Construction) specialists focus on installing subsea infrastructure, while Fpso (Floating Production Storage and Offloading) workers operate and maintain offshore production platforms. Both roles require offshore safety certifications and involve working in offshore environments, but their core responsibilities differ significantly in function and scope.

More about FPLC jobs
What states have the most Fplc jobs? States with the most job openings for Fplc jobs include:
Infographic showing various Fplc job openings in the United States as of August 2026, with employment types broken down into 86% Full Time, 7% Part Time, and 7% Contract. Highlights an 100% In-person job distribution, with an average salary of $69,125 per year, or $33.2 per hour.

Scientist-Principal Scientist, Protein Design & Structure

Superluminal Medicines, Inc.

Boston, MA • On-site

Other

Re-posted 6 days ago


Job description

Position Summary

We are seeking a highly innovative and experienced Scientist/Senior Scientist/Principal Scientist to lead GPCR protein engineering and production efforts. The successful candidate will be a subject matter expert (SME) in membrane protein biochemistry, responsible for developing and implementing strategies to express, purify, and characterize challenging G-protein coupled receptors (GPCRs) to support structural biology, biophysics, and drug discovery programs. This role involves hands-on laboratory work and scientific leadership. 

Key Responsibilities

  • Protein Engineering Strategy: Design, execute, and optimize constructs for GPCR expression.
  • Expression & Purification: Drive the development of high-throughput protein expression (mammalian/insect cells) and purification workflows, ensuring high-quality, homogeneous protein for assays and structural studies (Cryo-EM).
  • Cross-Functional Collaboration: Partner with pharmacology, structural biology, and medicinal chemistry teams to support drug discovery projects and advance programs from hit-to-lead and lead optimization.
  • Technical Leadership: Serve as a SME on GPCR protein sciences in internal and external project teams; evaluate and implement new technologies.
  • Scientific Documentation & Communication: Document experiments in ELN, present data at internal/external meetings, and publish research findings.

Required Qualifications

  • Ph.D. in Biochemistry, Molecular Biology, Biophysics, or a related field with 2+ years (Scientist), 5+ years (Senior Scientist), or 8+ years (Principal Scientist) of relevant experience; or a master's or bachelor's degree in a related field with commensurate industry experience. 
  • Deep knowledge of GPCR biology and membrane protein structure-function relationships.
  • Proven expertise in molecular biology (cloning, construct design, mutagenesis).
  • Hands-on experience in protein purification of GPCRs using FPLC (affinity, SEC).
  • Familiarity with protein stabilization techniques (e.g., antibody fragments, fusion partners, mutagenesis).
  • Excellent communication, interpersonal, and leadership skills.

Preferred Qualifications

  • Experience with structural biology methods (data collection and processing for Cryo-EM).
  • Experience in laboratory automation in protein sciences & purification.
  • Background in computational protein design tools (e.g., Rosetta, AI/ML-driven prediction).