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Epigenomics Jobs (NOW HIRING)

Natera

Scientist, Research (Epigenomics)

San Carlos, CA · On-site

In this role, you will apply your expertise in epigenomics to develop novel cell-free DNA diagnostic assays for cancer detection and disease monitoring. We are looking for a meticulous and dedicated ...

Natera

Scientist, Research (Epigenomics)

San Carlos, CA · On-site

$116K - $146K/yr

In this role, you will apply your expertise in epigenomics to develop novel cell-free DNA diagnostic assays for cancer detection and disease monitoring. We are looking for a meticulous and dedicated ...

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$25K

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How much do epigenomics jobs pay per year?

As of Jun 21, 2026, the average yearly pay for epigenomics in the United States is $59,022.00, according to ZipRecruiter salary data. Most workers in this role earn between $49,000.00 and $66,500.00 per year, depending on experience, location, and employer.

What are some common challenges faced by professionals working in epigenomics research teams?

Professionals in epigenomics often encounter challenges such as managing and analyzing large-scale, complex datasets generated from sequencing technologies. Collaborating with multidisciplinary teams—such as bioinformaticians, molecular biologists, and statisticians—is essential for interpreting results and troubleshooting experimental protocols. Keeping up with rapid technological advances and evolving best practices in both wet lab and computational methods can also be demanding. However, these challenges provide opportunities to develop cross-disciplinary skills and contribute to high-impact discoveries.

What are the key skills and qualifications needed to thrive as an Epigenomics Scientist, and why are they important?

To thrive as an Epigenomics Scientist, you need a strong background in molecular biology, genetics, and bioinformatics, typically supported by a PhD or advanced degree in a relevant field. Proficiency with high-throughput sequencing technologies, data analysis platforms like R or Python, and experience with techniques such as ChIP-seq or DNA methylation assays are crucial. Analytical thinking, attention to detail, and effective communication are important soft skills for interpreting complex data and collaborating with multidisciplinary teams. These skills are essential for advancing research, accurately analyzing epigenetic modifications, and driving discoveries in health and disease.

What is epigenomics?

Epigenomics is the study of the complete set of epigenetic modifications on the genetic material of a cell, known as the epigenome. These modifications, such as DNA methylation and histone modification, do not change the underlying DNA sequence but can influence gene expression and cellular function. Epigenomics research helps scientists understand how genes are regulated in different cell types, during development, and in response to environmental factors. This field is crucial for understanding complex diseases, including cancer, and can lead to new therapeutic strategies.

What is the difference between Epigenomics vs Genomics Technician?

AspectEpigenomicsGenomics Technician
Required CredentialsBachelor's degree in biology, genetics, or related field; laboratory experienceBachelor's degree in biology, genetics, or related field; laboratory skills
Work EnvironmentResearch labs focusing on gene regulation and epigenetic modificationsGenetics labs performing DNA sequencing and analysis
Industry UsageAcademic, biotech, pharmaceutical sectorsResearch institutions, biotech companies

Epigenomics involves studying heritable changes in gene expression caused by mechanisms other than DNA sequence, such as DNA methylation. Genomics technicians focus on sequencing and analyzing DNA. While both roles require similar educational backgrounds and work in laboratory settings, epigenomics emphasizes gene regulation mechanisms, whereas genomics centers on DNA sequence analysis.

More about Epigenomics jobs
What job categories do people searching Epigenomics jobs look for? The top searched job categories for Epigenomics jobs are:
Epigenomics jobs near you
Infographic showing various Epigenomics job openings in the United States as of June 2026, with employment types broken down into 99% Full Time, and 1% Part Time. Highlights an 96% Physical, 1% Hybrid, and 3% Remote job distribution, with an average salary of $59,022 per year, or $28.4 per hour.

Scientist, Research (Epigenomics)

Natera

San Carlos, CA • On-site

Other

Posted 18 days ago

Natera rating

7.7

Company rating: 7.7 out of 10

Based on 35 frontline employees who took The Breakroom Quiz

48th of 103 rated laboratories

Job description

The Molecular Biology Research team at Natera is looking for a highly motivated Scientist to join our group focused on developing and advancing Natera's oncology product portfolio. In this role, you will apply your expertise in epigenomics to develop novel cell-free DNA diagnostic assays for cancer detection and disease monitoring.

We are looking for a meticulous and dedicated candidate with hands-on laboratory experience in epigenetic assay development who can work effectively in a fast-paced environment to ensure the highest quality clinical assays are developed and launched for our patients. The right candidate maintains broad knowledge of state-of-the-art principles in epigenomics and molecular biology with an understanding of their applicability to oncology research.

PRIMARY RESPONSIBILITIES: 

  • Independently plan and execute experiments of moderate complexity to develop next-generation automated nucleic acid based diagnostic workflows
  • Design and optimize assays leveraging epigenetic signals (e.g., methylation) from cell-free DNA for clinical applications
  • Perform basic data analysis (e.g., JMP, R, Python, Excel), write study protocols, and SOPs
  • Collaborate cross-functionally with other teams, including data scientists and bioinformaticians
  • Generate reports and presentations to communicate findings directly to peers and management
  • Contribute insights towards experimental findings and troubleshoot laboratory processes and protocols.

QUALIFICATIONS: 

  • Degree in molecular biology, epigenomics, biochemistry, or closely related fields
  • PhD with 2 years of experience, or Master's with a minimum of 5 years experience in assay development for the life science industry, with demonstrated focus on epigenetic research

KNOWLEDGE AND SKILLS: 

  • Expertise in liquid biopsy assay development is strongly preferred
  • Experience in Next-Generation Sequencing (NGS) combined with hands-on experience in epigenetic techniques is a strong plus
  • Extensive hands-on experience with nucleic acid techniques (DNA manipulation, PCR, qPCR, DNA quantitation/analysis, hybrid capture)
  • Experience developing or executing assays using automated liquid handlers is preferred
  • Must have experience performing data analysis with Excel (or JMP). Working knowledge of epigenetic analysis tools (Bismark, methylKit, or equivalent) is a plus
  • Strong analytical and problem solving skills
  • Skilled at cross-functional communication and coordination

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