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Entry Level Protein Engineering Scientist Jobs in Tennessee

Inotiv

Research Scientist, Proteomics

Nashville, TN · On-site

Protein extraction and lysis, reduction and alkylation, and enzymatic (e.g., tryptic) digestion ... Operating, programming, and maintaining automated liquid-handling and bead-based sample-preparation ...

WSP

Early Career Environmental Scientist

Brentwood, TN · On-site

$71K - $93K/yr

... engineers across WSP to deliver impactful results for our clients. Your Impact * Under general ... entry-level technical assistance on various environmental issues. * Generate complete, accurate ...

L3HHCM20

Associate, Electrical Engineer

Nashville, TN · On-site

This level is an entry-level professional role with broad theoretical job knowledge and guided ... Electrical Engineering Technology, Computer Science or related field or have completed their ...

Stefanini

Greenhouse Technician

Memphis, TN · On-site

$13.75 - $16/hr

EXPERIENCE: Entry level experience in greenhouse, landscaping, horticulture, gardening ... Sampling genetically engineered plant tissue for DNA and Protein testing in search of desired ...

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Entry Level Protein Engineering Scientist information

What are the key skills and qualifications needed to thrive as an entry level protein engineering scientist?

To thrive as an Entry Level Protein Engineering Scientist, you need a solid background in molecular biology, biochemistry, and protein engineering, typically supported by a relevant bachelor’s or master’s degree. Proficiency in laboratory techniques such as PCR, mutagenesis, chromatography, and familiarity with bioinformatics tools and software like PyMOL or BLAST is important. Attention to detail, strong analytical thinking, and effective teamwork enable you to excel in experimental design and data interpretation. These skills are crucial for advancing research goals, ensuring accurate results, and contributing to collaborative scientific projects.

What does an entry level protein engineering scientist do?

An Entry Level Protein Engineering Scientist assists in the design, modification, and analysis of proteins to improve their properties for specific applications, such as drug development or industrial processes. They typically work in laboratories, conducting experiments, analyzing data, and collaborating with senior scientists to optimize protein function. Responsibilities may include molecular cloning, protein expression and purification, and using computational tools for protein modeling. This role often serves as a starting point for a career in biotechnology or pharmaceutical research, providing hands-on experience with advanced laboratory techniques and scientific problem-solving.

What are some typical challenges faced by entry level protein engineering scientists when starting in the field?

Entry-level protein engineering scientists often encounter challenges such as adapting to complex laboratory protocols, mastering advanced analytical techniques, and interpreting experimental data accurately. Collaborating effectively within multidisciplinary teams and efficiently documenting research findings are also common hurdles. However, these challenges present valuable learning opportunities and, with mentorship and regular feedback, new scientists quickly build confidence and expertise.
What are the most commonly searched types of Protein Engineering Scientist jobs in Tennessee? The most popular types of Protein Engineering Scientist jobs in Tennessee are:
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What cities in Tennessee are hiring for Entry Level Protein Engineering Scientist jobs? Cities in Tennessee with the most Entry Level Protein Engineering Scientist job openings:
Entry Level Protein Engineering Scientist jobs near you
Infographic showing various Entry Level Protein Engineering Scientist job openings in Tennessee as of August 2026, with employment types broken down into 88% Full Time, 6% Part Time, 5% Contract, and 1% Nights. Highlights an 85% Physical, 6% Hybrid, and 9% Remote job distribution.

Scientist Antibody Discovery

St. Jude Children's Research Hospital

Memphis, TN • On-site

$86K - $154K/yr

Full-time

Posted 26 days ago

St. Jude Children's Research Hospital rating

8.6

Company rating: 8.6 out of 10

Based on 12 frontline employees who took The Breakroom Quiz

41st of 1,058 rated hospitals

Job description

Join an excellent team of researchers dedicated to coming closer to the mission of St. Jude Children's Research Hospital, that no child will die at the dawn of life. Antibody Discovery Collaborative Centre (ADCC) within the Department of Host Microbe Interactions at St. Jude seeks a skilled and highly motivated candidate experienced in antibody discovery.
Candidates with experience in antibody discovery, protein engineering OR expression and validation of biologics are encouraged to apply.
What you will do:
  • Antibody discovery: Focus on display methods (phage, yeast, mammalian) and experience in building high-diversity libraries from synthetic and animal repertoires. Previous experience in integrating ML-based approaches with display methods would be preferred.
    • Experienced in designing discovery workflows and delivering panel of lead candidates for programs.
    • Apply in-vitro display methods for sequence discovery and ability to handle multiple screening arms for antigens.
    • Apply NGS methods to mine antibody pools for sequence discovery
    • Previous experience in library generation would be vital.
  • Protein Sciences: Develop and optimize high-throughput mammalian cell-based production platforms for recombinant antibodies, antigens, and other biologics
    • Work closely with mAb discovery platforms to support molecular biology workflows; design and execute construct generation for antibody expression.
    • Perform DNA preparations to generate high-quality plasmid material for mammalian cell transfection.
    • Establish scalable transient and stable expression workflows in CHO, HEK293, and other mammalian expression systems.
    • Purification using AKTA chromatography systems.
    • High-Performance Liquid Chromatography Size Exclusion Chromatography (HPLC-SEC) analysis of purified proteins.
    • Molecular assessment of early-stage development candidates (polyreactivity ELISA, CE-SDS, SEC-MALS, DSF)
  • Maintain accurate and timely ELN data

Preferred skills:
  • Experience with merging cryo-EM techniques with epitope analysis of antibody repertoires
  • Experience with high-throughput automated protein purification systems (e.g. Kingfisher)
  • Experience with antibody-related bioinformatic/software packages.
  • Expertise in high-throughput molecular biology approaches for construct and library generation.
  • Experience with mAb characterization techniques (FACS, BLI, epitope binning).

Minimum Education and/or Training:
  • Bachelor's degree in relevant scientific area is required.

Minimum Experience:
  • Eight (8) years of relevant work experience is required
  • Six (6) years of relevant work experience is required with a Master's degree
  • Three (3) years of relevant work experience is required with a PhD

Compensation
In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $86,320 - $154,960 per year for the role of Scientist Antibody Discovery.
Explore our exceptional benefits!
St. Jude is an Equal Opportunity Employer
No Search Firms
St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.

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