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School of Medicine:

Established in 1930, Duke University School of Medicine is the youngest of the nation's top medical schools. Ranked sixth among medical schools in the nation, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where interdisciplinary collaboration is embraced and great ideas accelerate translation of fundamental scientific discoveries to improve human health locally and around the globe. Composed of more than 2,600 faculty physicians and researchers, nearly 2,000 students, and more than 6,200 staff, the Duke University School of Medicine along with the Duke University School of Nursing, and Duke University Health System comprise Duke Health, a world-class academic medical center. The Health System encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Health Integrated Practice, Duke Primary Care, Duke Home Care and Hospice, Duke Health and Wellness, and multiple affiliations.

Be You.

The Duke Cancer Institute (DCI) is seeking a Clinical Research Nurse Coordinator to join our GU (Genitourinary) Clinical Research Program. In this role, you will provide leadership and hands-on coordination for multiple, complex oncology clinical trials, including studies involving Investigational Products (IP). You will play a critical role in advancing cancer research by supporting participants throughout the research process while ensuring studies are conducted safely, ethically, and in full compliance with regulatory and institutional requirements.

You will work closely with Principal Investigators, sponsors, study teams, and the Oncology Clinical Research Unit (CRU) to bring innovative therapies to patients. This role blends direct patient care, clinical research operations, and collaborative leadership, making it ideal for a nurse who is passionate about oncology research, patient advocacy, and continuous learning.

Minimum Requirements

• Graduation from an accredited BSN, Associate Degree in Nursing, or Nursing Diploma program
• Current or compact Registered Nurse (RN) licensure in the state of North Carolina
• BLS certification
• Minimum of 12 months of clinical nursing experience
• Ability to maintain compliance with Duke, hospital, and unit-specific training and competency requirements
• Active RN status with the North Carolina Board of Nursing (NCBON)

Preferred Qualifications

• At least two (2) years of patient-facing clinical research or direct patient care experience
• Experience with clinical trial activities such as screening, consenting, protocol implementation, and research involving human participants
• Experience working with oncology patient populations
• Strong organizational skills with the ability to manage multiple, complex clinical trials simultaneously
• Experience using electronic health records (EHR), Electronic Data Capture (EDC) systems, and/or Clinical Trial Management Systems (CTMS)
• Excellent written and verbal communication skills

Be Bold.

In this role, you will coordinate, manage, and lead all aspects of assigned oncology clinical trials, ensuring high-quality execution and participant-centered care.

• Coordinate clinical trial operations and site management, including feasibility assessments, participant recruitment and retention strategies, and study start-up and closeout activities
• Recruit, screen, consent, enroll, schedule, and conduct study visits in collaboration with Principal Investigators and study teams; document all study activities accurately and in compliance with protocol requirements
• Ensure regulatory and institutional compliance by maintaining regulatory binders, enrollment logs, delegation of authority logs, adverse event documentation, and required submissions
• Serve as the primary liaison between sponsors, monitors, investigators, and internal study personnel; communicate proactively and escalate issues appropriately
• Manage study data and documentation, including accurate and timely EDC entry; identify and resolve data discrepancies while ensuring data security and integrity
• Monitor study finances, including participant care costs, study payments, budget development support, and financial milestone tracking
• Provide leadership and mentorship within the research team; serve as an expert resource and support training and professional development of colleagues
• Promote ethical research conduct by clearly distinguishing clinical care from research activities for participants and staff, reinforcing informed consent principles and regulatory standards
• Deliver direct RN clinical care in the research setting, including medication administration, chemotherapy administration, patient assessments, adverse event recognition, patient education, and collaboration with the interdisciplinary medical team

Choose Duke.

The Duke Cancer Institute is a nationally recognized leader in cancer research, treatment, and prevention. By joining the GU Clinical Research Program, you will contribute to cutting-edge oncology trials that directly impact patient outcomes and advance scientific discovery.

At Duke, you'll find a collaborative, mission-driven environment that values excellence, integrity, and compassion. You'll have access to robust professional development opportunities, participation in scientific presentations and publications, and the support of a highly engaged multidisciplinary team.