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Downstream Process Jobs in Michigan (NOW HIRING)

Advanced Drainage Systems

Downstream Technician

Owosso, MI

$19.50 - $25.75/hr

We value diverse perspectives, recognizing that they drive better ideas, processes, and performance. Our workplace is built on respect, inclusivity, and shared responsibility, ensuring every team ...

Whirlpool

Manager, General Finance

Benton Harbor, MI · On-site

$102K - $140K/yr

Lead cross-functional planning and forecasting processes, identifying upstream and downstream process and control implications across finance and business functions * Supervise, evaluate, and develop ...

fairlife

Processing Manager

Coopersville, MI · On-site

... process flow and fluid mass balance * 5-10 years' experience in Fluid Milk or Value-Added ... downstream (Packaging and Supply Chain) * Ability to implement fundamental Lean Principles ...

fairlife

Processing Manager

Coopersville, MI

$10K/mo

... process flow and fluid mass balance * 5-10 years' experience in Fluid Milk or Value-Added ... downstream (Packaging and Supply Chain) * Ability to implement fundamental Lean Principles ...

fairlife LLC

Processing Manager

Coopersville, MI · On-site

... process flow and fluid mass balance * 5-10 years' experience in Fluid Milk or Value-Added ... downstream (Packaging and Supply Chain) * Ability to implement fundamental Lean Principles ...

fairlife

Processing Manager

Coopersville, MI

... process flow and fluid mass balance * 5-10 years' experience in Fluid Milk or Value-Added ... downstream (Packaging and Supply Chain) * Ability to implement fundamental Lean Principles ...

Michigan Farm Bureau

Senior HRIS Analyst

Lansing, MI · On-site

$81K - $101K/yr

... downstream processes. Manage vendor relationships as the primary point of contact for troubleshooting, platform implementations, updates, and ongoing support. Qualifications Senior HRIS Analyst ...

Michigan Farm Bureau

Senior HRIS Analyst

Lansing, MI

$91K - $116K/yr

... downstream processes. Manage vendor relationships as the primary point of contact for troubleshooting, platform implementations, updates, and ongoing support. Qualifications Senior HRIS Analyst ...

Michigan Farm Bureau

Senior HRIS Analyst

Lansing, MI · On-site

$91K - $116K/yr

... downstream processes. Manage vendor relationships as the primary point of contact for troubleshooting, platform implementations, updates, and ongoing support. Qualifications Senior HRIS Analyst ...

Michigan Farm Bureau

Senior HRIS Analyst (Lansing)

Lansing, MI · On-site

$91K - $116K/yr

... downstream processes. Manage vendor relationships as the primary point of contact for troubleshooting, platform implementations, updates, and ongoing support. Qualifications Senior HRIS Analyst ...

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Downstream Process information

What are some common challenges faced by professionals working in downstream process roles within biomanufacturing?

Professionals in downstream process roles often encounter challenges such as optimizing purification steps to maximize yield and product purity while minimizing costs and processing time. They must also troubleshoot issues related to equipment performance, scalability, and regulatory compliance, especially when transitioning from lab-scale to large-scale production. Collaboration with upstream teams, quality assurance, and engineering is critical to address these challenges and ensure a smooth workflow. Staying current with technological advances and regulatory requirements also plays a significant role in day-to-day success.

What are the key skills and qualifications needed to thrive as a Downstream Process Engineer, and why are they important?

To thrive as a Downstream Process Engineer, you need a solid background in chemical or biochemical engineering, knowledge of purification techniques, and typically a relevant degree. Familiarity with process control systems, chromatography, filtration technologies, and GMP compliance, as well as certifications like Six Sigma, are commonly required. Strong problem-solving, teamwork, and communication skills help you excel in cross-functional teams and address complex production challenges. These skills ensure efficient, high-quality product recovery and compliance with industry standards in biomanufacturing environments.

What is the difference between Downstream Process vs Upstream Process?

AspectDownstream ProcessUpstream Process
PurposePurifies and isolates the target product from the mixtureProduces the initial product, such as cell culture or fermentation
ActivitiesFiltration, chromatography, centrifugation, purificationCell growth, fermentation, media preparation
Work EnvironmentLaboratories, bioprocessing facilitiesBioreactors, fermentation tanks, labs
Required SkillsBioprocessing techniques, chromatography, filtrationMicrobiology, cell culture, fermentation technology

Downstream Process focuses on purifying the product, while Upstream Process involves producing the raw material. Both are essential steps in biopharmaceutical manufacturing, often working sequentially to ensure high-quality product output.

What is a Downstream Process in biotechnology?

A Downstream Process refers to the series of steps involved in the purification and recovery of biological products, such as proteins, enzymes, or antibodies, after they have been produced by microorganisms or cells during fermentation or cell culture. It typically includes cell separation, product isolation, purification, and polishing to achieve the desired product quality and purity. Downstream processing is crucial for ensuring that biopharmaceutical products meet regulatory and safety standards before they reach the market.
What are popular job titles related to Downstream Process jobs in Michigan? For Downstream Process jobs in Michigan, the most frequently searched job titles are:
What job categories do people searching Downstream Process jobs in Michigan look for? The top searched job categories for Downstream Process jobs in Michigan are:
Downstream Process jobs near you
Infographic showing various Downstream Process job openings in Michigan as of July 2026, with employment types broken down into 18% Locum Tenens, 74% Full Time, 4% Part Time, 3% Contract, and 1% Summer. Highlights an 85% Physical, 4% Hybrid, and 11% Remote job distribution.
Press Brake Programmer/Operator (3rd Shift)

Press Brake Programmer/Operator (3rd Shift)

Impact Fab

Holland, MI • On-site

$16.50 - $21.75/hr

Full-time

Re-posted 26 days ago

Job description

Are you looking for a new opportunity where you can make an immediate impact in a fast-paced, growing West Michigan company? Do you enjoy metal fabrication and want to grow your skills? If so, Impact Fab could be a great fit for you. We are seeking a 3rd Press Brake Programmer/Operator to join our team.
Work Schedule: 8:00 pm - 6:30 am Monday night - Friday morning with a long weekend every week
Position Summary
This role is responsible for programming, setting up, and operating press brakes to produce accurate, high-quality formed parts. The mid-level operator is expected to work independently on standard jobs, troubleshoot basic issues, and support flow on the floor without constant oversight.
This is not a "button pusher" role - this is a thinking operator who understands bend sequences, material behavior, and how their work impacts downstream welding and assembly.
Key Responsibilities
Programming & Setup
  • Determine proper bend sequence, tooling selection, and tonnage requirements
  • Set up machines efficiently to minimize downtime and changeover time
  • Verify first-piece accuracy before releasing to production

Operation
  • Operate press brake to form parts to print specifications
  • Adjust programs and setups as needed to maintain quality
  • Monitor part quality throughout the run (angles, dimensions, flatness)

Print & Part Interpretation
  • Read and interpret blueprints, including:
    • Bend callouts
    • Tolerances
    • GD&T basics (as applicable)
  • Understand how forming affects downstream processes (fit-up, welding)

Quality & Accountability
  • Perform in-process inspections using calipers, angle gauges, etc.
  • Document required checks per job traveler or print
  • Identify and stop production on nonconforming parts
  • Work with Quality (Jeff/inspection team) when issues arise

Continuous Improvement
  • Suggest improvements to bend sequences, tooling, and setups
  • Reduce scrap and rework through better process control
  • Support lean initiatives (5S, setup reduction, flow improvement)

Team Support
  • Assist less experienced operators when needed
  • Communicate clearly with upstream (laser) and downstream (weld) teams
  • Maintain clean and organized work area

Successful candidates will have:
Experience
  • 3-7 years press brake operation experience in a fabrication environment
  • Experience programming CNC press brakes (not just running parts)
  • Familiar with a variety of materials (steel, stainless, aluminum)

Technical Skills
  • Strong blueprint reading skills
  • Solid understanding of:
    • Bend allowance / bend deduction
    • Grain direction
    • Springback
  • Comfortable using basic inspection tools

Preferred (Not Required, But Valuable)
  • Experience with offline programming software (e.g., AutoPOL, VPSS, RADAN)
  • GD&T familiarity
  • Experience in job shop / high-mix, low-volume environment

Performance Expectations (How You'll Be Measured)
  • Quality: Parts meet print without rework
  • Productivity: Jobs completed within estimated time
  • Setup Efficiency: Reduced setup and changeover time
  • Scrap Reduction: Minimal material waste
  • Ownership: Solves problems without waiting to be told

Impact Fab is a custom fabrication shop located in Holland, Michigan. We specialize in short run productions; machine build and part prototyping. Our commitment to quality service, quality parts, and genuine respect have earned us the loyalty of our customers and a prominent place in the design for manufacturing market.
If this sounds like a position for you and we are the kind of company you see yourself with, apply today for immediate consideration! To learn more about our organization, please visit our website at www.impactfab.com.

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